A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking
Aguilar PS, Fröhlich F, Rehman M, Shales M, Ulitsky I, Olivera-Couto A, Braberg H, Shamir R, Walter P, Mann M, Ejsing CS, Krogan NJ, Walther TC. A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking. Nature Structural & Molecular Biology 2010, 17: 901-908. PMID: 20526336, PMCID: PMC3073498, DOI: 10.1038/nsmb.1829.Peer-Reviewed Original ResearchConceptsGDP/GTP exchange factorQuantitative genetic interaction mapGenetic interaction mapSphingolipid metabolismGTP exchange factorExchange factorMotif analysisEndosomal traffickingMembrane biologyInteraction mapEisosomesE-MAPGenesRom2MetabolismRho1New componentsTraffickingBiologyRegulationRhO2UncoversIdentification