Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs
Marquart K, Mathis N, Mollaysa A, Müller S, Kissling L, Rothgangl T, Schmidheini L, Kulcsár P, Allam A, Kaufmann M, Matsushita M, Haenggi T, Cathomen T, Kopf M, Krauthammer M, Schwank G. Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs. Nature Methods 2024, 21: 2084-2093. PMID: 39313558, DOI: 10.1038/s41592-024-02418-z.Peer-Reviewed Original Research