1995
Heat-insoluble cryoglobulin in a patient with essential type I cryoglobulinemia and massive cryoglobulin-occlusive glomerulonephritis
Ishimura E, Nishizawa Y, Shoji S, Okumura M, Nishitani H, Kim C, Watanabe Y, Wakasa K, Morii H, Kashgarian M. Heat-insoluble cryoglobulin in a patient with essential type I cryoglobulinemia and massive cryoglobulin-occlusive glomerulonephritis. American Journal Of Kidney Diseases 1995, 26: 654-657. PMID: 7573022, DOI: 10.1016/0272-6386(95)90604-5.Peer-Reviewed Original ResearchConceptsEnd-stage renal failureMonoclonal IgG-kappaType I cryoglobulinemiaOnset of diseaseElectron-dense depositsEssential cryoglobulinemiaRenal failureClinical courseRenal biopsyNephrotic syndromeIgG kappaLower extremitiesCryoglobulinsGelatinous appearanceGlomerular capillariesCryoglobulinemiaGlomerulonephritisInitial onsetBiopsyDiseaseOnsetYears
1986
Progressive Glomerular Sclerosis in Experimental Antiglomerular Basement Membrane Glomerulonephritis
Foellmer H, Sterzel R, Kashgarian M. Progressive Glomerular Sclerosis in Experimental Antiglomerular Basement Membrane Glomerulonephritis. American Journal Of Kidney Diseases 1986, 7: 5-11. PMID: 3510536, DOI: 10.1016/s0272-6386(86)80050-6.Peer-Reviewed Original ResearchConceptsGlomerular filtration rateAntiglomerular basement membrane glomerulonephritisProgressive glomerular sclerosisGlomerular sclerosisPara-aminohippuric acidGlomerular hypercellularityFiltration fractionWistar ratsInitial inflammatory changesNormal renal clearanceIntrinsic glomerular cellsChronic glomerulosclerosisRenal insufficiencyInflammatory changesAcute phaseChronic phaseSignificant proteinuriaFiltration rateLeukocytic infiltrationCrescent formationFunctional abnormalitiesSclerotic processRenal clearanceGlomerular cellsGlomerulonephritisA Review of Nephrotic Syndrome Associated With Chronic Lymphocytic Leukemia
Seney F, Federgreen W, Stein H, Kashgarian M. A Review of Nephrotic Syndrome Associated With Chronic Lymphocytic Leukemia. JAMA Internal Medicine 1986, 146: 137-141. PMID: 3942445, DOI: 10.1001/archinte.1986.00360130167023.Peer-Reviewed Original ResearchConceptsChronic lymphocytic leukemiaNephrotic syndromeLymphocytic leukemiaNephrotic Syndrome AssociatedCommon glomerular lesionImmune complex diseaseRenal diseaseMembranoproliferative glomerulonephritisCellular immunitySyndrome AssociatedGlomerular lesionsImmunoglobulin productionPatientsAvailable evidenceSyndromeLeukemiaDiseaseGlomerulonephritisLesionsImmunity
1980
The significance of electron dense deposits in mild lupus nephritis.
Domoto D, Kashgarian M, Hayslett J, Adler M, Siegel N. The significance of electron dense deposits in mild lupus nephritis. The Yale Journal Of Biology And Medicine 1980, 53: 317-24. PMID: 7445538, PMCID: PMC2595828.Peer-Reviewed Original ResearchConceptsMild lupusSubendothelial depositsDiffuse proliferative lesionsPercent of patientsDiffuse proliferative glomerulonephritisRate of progressionElectron-dense depositsLupus nephritisSubsequent biopsyPoor prognosisProliferative glomerulonephritisDeteriorating courseMild lesionsProliferative lesionsPatientsProgressionDense depositsLupusLesionsLight microscopyWide variationGlomerulonephritisNephritisBiopsyPrognosis
1977
SEQUENTIAL HISTOLOGIC CHANGES IN UNTREATED MESANGIALCAPILLARY GLOMERULONEPHRITIS (MCGN)
Siegel N, Kashgarian M. SEQUENTIAL HISTOLOGIC CHANGES IN UNTREATED MESANGIALCAPILLARY GLOMERULONEPHRITIS (MCGN). Pediatric Research 1977, 11: 557-557. DOI: 10.1203/00006450-197704000-01126.Peer-Reviewed Original ResearchInterstitial fibrosisMesangial sclerosisSubendothelial depositsSecond renal biopsyDiffuse mesangial proliferationHistologic improvementSteroid therapyImmunosuppressive agentsRenal biopsyInitial diagnosisMesangial proliferationPatientsSubepithelial depositsSequential histologicSclerosisBasement membraneFibrosisRecent dataSignificant changesProliferationProgressive changesGlomerulonephritisBiopsyHistologicTherapy
1972
CLINICOPATHOLOGICAL CORRELATIONS OF PRIMARY HÆMATURIA
Hendler E, Kashgarian M, Hayslett J. CLINICOPATHOLOGICAL CORRELATIONS OF PRIMARY HÆMATURIA. The Lancet 1972, 299: 458-463. PMID: 4109816, DOI: 10.1016/s0140-6736(72)90121-3.Peer-Reviewed Original ResearchConceptsRenal diseaseProliferative glomerulonephritisPathological lesionsMild proliferative glomerulonephritisUrinary tract lesionsUrinary protein excretionGroup of patientsTypes of glomerulonephritisSevere proliferative glomerulonephritisType of lesionIntercurrent infectionRenal functionRenal biopsyProtein excretionPrimary lesionClinicopathological correlationDistribution of ageCorrect diagnosisPatientsGlomerulonephritisLesionsYoung adultsDiseaseHæmorrhageUseful index
1971
Effect of azathioprine in patients with lupus glomerulonephritis
Hayslett J, Cook C, Kashgarian M, Spargo B. Effect of azathioprine in patients with lupus glomerulonephritis. Pediatric Research 1971, 5: 384-385. DOI: 10.1203/00006450-197108000-00058.Peer-Reviewed Original ResearchSevere glomerulonephritisRenal failureLupus glomerulonephritisNephrotic syndromeRenal lesionsMonths of therapyEvidence of progressionSevere renal failureMonths of treatmentEffect of azathioprinePatient's proteinuriaMembranous nephropathySevere nephritisHistological featuresIntensive treatmentMembranous changesGlomerulonephritisInexorable progressionProliferative lesionsPatientsLow dosesLesionsStriking decreaseAzathioprineMonths
1969
Progression of Lipoid Nephrosis to Renal Insufficiency
Hayslett J, Krassner L, Bensch K, Kashgarian M, Epstein F. Progression of Lipoid Nephrosis to Renal Insufficiency. New England Journal Of Medicine 1969, 281: 181-187. PMID: 5790494, DOI: 10.1056/nejm196907242810402.Peer-Reviewed Original Research