A Digital Atlas to Characterize the Mouse Brain Transcriptome
Carson JP, Ju T, Lu HC, Thaller C, Xu M, Pallas SL, Crair MC, Warren J, Chiu W, Eichele G. A Digital Atlas to Characterize the Mouse Brain Transcriptome. PLOS Computational Biology 2005, 1: e41. PMID: 16184189, PMCID: PMC1215388, DOI: 10.1371/journal.pcbi.0010041.Peer-Reviewed Original ResearchConceptsDigital atlasUser queriesQuery patternsAnnotation methodData modalitiesMassive amountsTypes of dataExpression patternsMouse brain transcriptomeGene expression patternsComputational methodsCommon framePostnatal mouse brainBrain transcriptomeQueriesCandidate genesComplex tissuesCellular resolutionGenesMutations in Drosophila sec15 Reveal a Function in Neuronal Targeting for a Subset of Exocyst Components
Mehta SQ, Hiesinger PR, Beronja S, Zhai RG, Schulze KL, Verstreken P, Cao Y, Zhou Y, Tepass U, Crair MC, Bellen HJ. Mutations in Drosophila sec15 Reveal a Function in Neuronal Targeting for a Subset of Exocyst Components. Neuron 2005, 46: 219-232. PMID: 15848801, DOI: 10.1016/j.neuron.2005.02.029.Peer-Reviewed Original ResearchConceptsExocyst componentsComplex of proteinsCell polaritySec15Specific cell adhesionSpecific proteinsMutant neuronsSubcellular distributionCell adhesionCell lethalityExocystNeuronal targetingSec5Neurite outgrowthSynaptic specificityCell viabilityProteinSeparable functionsSec6Sec8SubcomplexMislocalizationYeastGenesComponents persist