2011
Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast
Wehrum MJ, Buhimschi IA, Salafia C, Thung S, Bahtiyar MO, Werner EF, Campbell KH, Laky C, Sfakianaki AK, Zhao G, Funai EF, Buhimschi CS. Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast. American Journal Of Obstetrics And Gynecology 2011, 204: 411.e1-411.e11. PMID: 21316642, PMCID: PMC3136625, DOI: 10.1016/j.ajog.2010.12.027.Peer-Reviewed Original ResearchConceptsVascular endothelial growth factorComplete placenta previaPlacenta previaEndothelial growth factorCytokeratin 7Growth factorExtravillous trophoblastsSystemic vascular endothelial growth factorMesenchymal transitionFree vascular endothelial growth factorInterstitial extravillous trophoblastsMesenchymal transition featuresPlacental growth factorAngiogenic factor profilesExpression of vimentinInvasive extravillous trophoblastsUncomplicated pregnanciesMyometrial invasionPregnant womenPreviaInvasive trophoblastFactor profileHistological specimensInvasive placentationSerum samples
2008
Relationships of maternal serum levels of vascular endothelial growth factor and tensile strength properties of the cervix in a rat model of chronic hypoxia
Sfakianaki AK, Buhimschi IA, Ravishankar V, Bahtiyar MO, Dulay AT, Buhimschi CS. Relationships of maternal serum levels of vascular endothelial growth factor and tensile strength properties of the cervix in a rat model of chronic hypoxia. American Journal Of Obstetrics And Gynecology 2008, 198: 223.e1-223.e7. PMID: 18226631, DOI: 10.1016/j.ajog.2007.09.054.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCervix UteriDisease Models, AnimalFemaleFetal HypoxiaPregnancyRatsRats, Sprague-DawleyTensile StrengthVascular Endothelial Growth Factor AConceptsMaternal serum levelsVascular endothelial growth factorSerum levelsSignificant inverse correlationChronic hypoxiaEndothelial growth factorMaternal serum vascular endothelial growth factorSerum vascular endothelial growth factorAdult Sprague-Dawley ratsGrowth factorFree serum levelsInverse correlationRat uterine cervixSprague-Dawley ratsGroups of animalsHPx groupNonpregnant controlsUterine cervixHypoxic chamberRat modelMaternal bloodCervical stiffnessCervixCervical strengthDay 21