2023
Caution needed in ascribing subthreshold symptoms as autism spectrum disorder: Commentary on “autistic traits distribution in different psychiatric conditions: A cluster analysis on the basis of the adult autism subthreshold spectrum (AdAS SPECTRUM) questionnaire”
Bertelli M, Boniotti V, Bianco A, Vannucchi G, Buonaguro E, Micai M, Fatta L, Rossi M, Pecchini E, Bizzari V, Conte M, Lombardi G, Corti S, Scior K, Azeem M, Hassiotis A, Baghdadli A, Scattoni M, Salvador-Carulla L, Javed A, Munir K. Caution needed in ascribing subthreshold symptoms as autism spectrum disorder: Commentary on “autistic traits distribution in different psychiatric conditions: A cluster analysis on the basis of the adult autism subthreshold spectrum (AdAS SPECTRUM) questionnaire”. Psychiatry Research 2023, 331: 115617. PMID: 38043410, DOI: 10.1016/j.psychres.2023.115617.Peer-Reviewed Original ResearchGenomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study
Abdi M, Aliyev E, Trost B, Kohailan M, Aamer W, Syed N, Shaath R, Gandhi G, Engchuan W, Howe J, Thiruvahindrapuram B, Geng M, Whitney J, Syed A, Lakshmi J, Hussein S, Albashir N, Hussein A, Poggiolini I, Elhag S, Palaniswamy S, Kambouris M, de Fatima Janjua M, Tahir M, Nazeer A, Shahwar D, Azeem M, Mokrab Y, Aati N, Akil A, Scherer S, Kamal M, Fakhro K. Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study. Genome Medicine 2023, 15: 81. PMID: 37805537, PMCID: PMC10560429, DOI: 10.1186/s13073-023-01228-w.Peer-Reviewed Original ResearchConceptsTandem repeat expansionsSingle nucleotide variantsGenetic architectureNovel ASD candidate genesWhole-genome sequencing dataMitochondrial DNA variantsASD candidate genesMulti-omics researchGenomic architectureRecessive variationMtDNA variantsCandidate genesDNA variantsSequencing dataRepeat expansionNumber variantsSNVs/indelsDe novoNon-consanguineous familyGenesGenetics guidelinesUnique resourcePathogenic variantsFamilyMedical Genetics guidelines
2022
International perspective on integrated care models in child and adult mental health
Shaligram D, Skokauskas N, Aragones E, Azeem M, Bala A, Bernstein B, Cama S, Canessa L, Silva F, Engelhard C, Garrido G, Guerrero A, Hunt J, Jadhav M, Martin S, Miliauskas C, Nalugya J, Nazeer A, Ong S, Robertson P, Sassi R, Seker A, Consortium C, Watkins M, Leventhal B. International perspective on integrated care models in child and adult mental health. International Review Of Psychiatry 2022, 34: 101-117. PMID: 35699101, DOI: 10.1080/09540261.2022.2059346.Peer-Reviewed Original ResearchConceptsCare modelCollaborative careAdolescent mental health servicesCollaborative care modelIntegrated care modelStepped care modelMental health servicesAdult mental healthLow-resource settingsMeasurement of outcomesPrimary careCoordinated careHealth servicesCare perspectiveOngoing quality improvementComplex healthcare systemMental healthCareHealthcare systemHealthcare policyWorkforce capacityMultidimensional impacts of coronavirus pandemic in adolescents in Pakistan: A cross sectional research
Imran N, Naz F, Sharif M, Liaqat S, Riaz M, Khawar A, Azeem M. Multidimensional impacts of coronavirus pandemic in adolescents in Pakistan: A cross sectional research. PLOS ONE 2022, 17: e0262325. PMID: 34986208, PMCID: PMC8730410, DOI: 10.1371/journal.pone.0262325.Peer-Reviewed Original Research
2021
Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder
Yadav S, Bhat A, Hashem S, Nisar S, Kamal M, Syed N, Temanni M, Gupta R, Kamran S, Azeem M, Srivastava A, Bagga P, Chawla S, Reddy R, Frenneaux M, Fakhro K, Haris M. Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder. Translational Psychiatry 2021, 11: 349. PMID: 34091591, PMCID: PMC8179928, DOI: 10.1038/s41398-021-01473-w.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderNeurobiology of ADHDHyperactivity disorderSevere brain injuryNew treatment modalitiesDevelopment of ADHDBrain circuit functionNovel clinical biomarkersChildhood-onset disordersStrong genetic associationNeurodevelopmental assessmentPremature birthADHD brainTreatment modalitiesBrain injuryBrain changesPrecise etiologyPsychiatric disordersAnimal modelsADHD patientsTherapeutic interventionsNeural abnormalitiesClinical biomarkersNeurodevelopmental issuesSignificant associationReducing the stigma of mental health disorders with a focus on low- and middle-income countries
Javed A, Lee C, Zakaria H, Buenaventura R, Cetkovich-Bakmas M, Duailibi K, Ng B, Ramy H, Saha G, Arifeen S, Elorza P, Ratnasingham P, Azeem M. Reducing the stigma of mental health disorders with a focus on low- and middle-income countries. Asian Journal Of Psychiatry 2021, 58: 102601. PMID: 33611083, DOI: 10.1016/j.ajp.2021.102601.Peer-Reviewed Original ResearchConceptsMental health disordersMental health servicesHealth disordersHealth servicesMental healthMiddle-income countriesMental health disease burdenGlobal public health challengePathways of careHealth seeking behaviourPublic health challengeMental health careMental health workforceMental health systemPopulation mental healthMental health policyPerception of healthComorbidity burdenPhysical comorbiditiesPoor outcomeSuboptimal treatmentDisease burdenNoncommunicable diseasesPrimary healthcareMental health resultsGender and Racial Disparities among US Psychiatry Residents: A Review of Trends
Chaudhary A, Naveed S, Saboor S, Safdar B, Azeem M, Khosa F. Gender and Racial Disparities among US Psychiatry Residents: A Review of Trends. Psychiatric Quarterly 2021, 93: 97-105. PMID: 33586128, DOI: 10.1007/s11126-021-09888-w.Peer-Reviewed Original ResearchConceptsPacific IslandersUS psychiatry residency programsAfrican American/BlackEthnic minoritiesRacial minoritiesReview of trendsAmerican/BlackAsian/Pacific IslandersNative American/ResidentsRacial trendsAmerican/Race/ethnicityRacial disparitiesMinorityResource bookGenderIslandersPsychiatry residency programsMedical graduatesWhitesYear 2011CouncilWomenRace
2020
A World Psychiatric Association Initiative to Increase Interest in Psychiatry as a Career in Qatar Medical Students: A Pilot Study.
Hankir A, Tom A, Ibrahim H, Rifai A, Shahwar D, Youssef A, Azeem M, Javed A, Imam Z, Zaman R. A World Psychiatric Association Initiative to Increase Interest in Psychiatry as a Career in Qatar Medical Students: A Pilot Study. Psychiatria Danubina 2020, 32: 135-138. PMID: 32890376.Peer-Reviewed Original ResearchGenetics of structural and functional brain changes in autism spectrum disorder
Hashem S, Nisar S, Bhat A, Yadav S, Azeem M, Bagga P, Fakhro K, Reddy R, Frenneaux M, Haris M. Genetics of structural and functional brain changes in autism spectrum disorder. Translational Psychiatry 2020, 10: 229. PMID: 32661244, PMCID: PMC7359361, DOI: 10.1038/s41398-020-00921-3.Peer-Reviewed Original ResearchConceptsASD patientsAutism spectrum disorderFunctional brain changesSpecific single nucleotide polymorphismsClinical managementIsolated disorderBrain changesSpectrum disorderTherapeutic interventionsFunctional changesNoninvasive imagingDisordersSingle nucleotide polymorphismsGenetic disordersPatientsRisk genesDevelopmental disordersSocial impairmentNeuropsychiatryASD diagnosisCommunicative behavior
2019
Association of genes with phenotype in autism spectrum disorder
Nisar S, Hashem S, Bhat A, Syed N, Yadav S, Azeem M, Uddin S, Bagga P, Reddy R, Haris M. Association of genes with phenotype in autism spectrum disorder. Aging 2019, 11: 10742-10770. PMID: 31744938, PMCID: PMC6914398, DOI: 10.18632/aging.102473.Peer-Reviewed Original ResearchConceptsASD risk genesRisk genesNovel candidate genesAssociation of genesGene transcriptionGenetic pathwaysNeuronal activity modulationCandidate genesGenesGenetic variantsPathophysiology of ASDPathwayHeterogeneous neurodevelopmental disorderRegulation processesActivity modulationSynaptic plasticityNeurodevelopmental disordersTranscriptionIdentificationGeneticsPhenotypeRolePlasticityAutism spectrum disorderField of neuroscienceChild and adolescent psychiatry training and services in the Middle East region: a current status assessment
Clausen C, Bazaid K, Azeem M, Abdelrahim F, Elgawad A, Alamiri B, AlAnsari A, Alhamzawi A, Al Mai A, Bakhiet A, Bashtawi M, Çuhadaroğlu F, Hedar M, Holdar M, Jabr S, Jafri A, Jumaian A, Moussa S, Osman A, Razjouyan K, Yanes E, Guerrero A, Skokauskas N. Child and adolescent psychiatry training and services in the Middle East region: a current status assessment. European Child & Adolescent Psychiatry 2019, 29: 51-61. PMID: 31190178, DOI: 10.1007/s00787-019-01360-2.Peer-Reviewed Original ResearchConceptsAdolescent mental health careMental healthMental health specialistsCross-sectional studyAdolescent mental health specialistsMental health careAdolescent psychiatry servicesMental health workforceAdolescent psychiatryAdolescent mental healthDistribution of childrenPsychiatry servicesAppropriate careHealth specialistsHealth workforcePsychiatry specialistsUnderdeveloped childrenAdditional childrenQualified childrenAdolescent psychiatristsHealth careAvailable childrenAdolescent psychiatry training programsWorkforce capacityCurrent postgraduate training
2017
Effectiveness of six core strategies based on trauma informed care in reducing seclusions and restraints at a child and adolescent psychiatric hospital
Azeem M, Aujla A, Rammerth M, Binsfeld G, Jones RB. Effectiveness of six core strategies based on trauma informed care in reducing seclusions and restraints at a child and adolescent psychiatric hospital. Journal Of Child And Adolescent Psychiatric Nursing 2017, 30: 170-174. PMID: 30129244, DOI: 10.1111/jcap.12190.Peer-Reviewed Original ResearchConceptsTrauma-Informed CareSeclusion/restraintInformed careMonths of studyHospitalized youthType of admissionLength of stayNumber of seclusionsNumber of admissionsUse of seclusionAdolescent psychiatric hospitalDisruptive behavior disordersRestraint episodesMajor diagnosesMedical recordsMore episodesMood disordersPsychiatric diagnosisPsychiatric hospitalHospital staffBehavior disorderCarePatientsAdmissionChildren
2014
Successful seclusion and restraint prevention effort in child and adolescent programs.
Caldwell B, Albert C, Azeem MW, Beck S, Cocoros D, Cocoros T, Montes R, Reddy B. Successful seclusion and restraint prevention effort in child and adolescent programs. Journal Of Psychosocial Nursing And Mental Health Services 2014, 52: 30-8. PMID: 25250792, DOI: 10.3928/02793695-20140922-01.Peer-Reviewed Original ResearchConceptsBuilding Bridges InitiativeYouth perspectivesNational effortsTrauma-informed environmentsUnited StatesPrevention effortsDifferent childrenArticleAdolescent programsSignificant shiftPast decadeCurrent articleSeclusionEffortsInitiativesProgramChildrenPerspectiveExperienceSupportDecadesUse of restraintsComparing stimulant effects in youth with ADHD symptoms and epilepsy
Gonzalez-Heydrich J, Hsin O, Gumlak S, Kimball K, Rober A, Azeem MW, Hickory M, Mrakotsky C, Torres A, Mezzacappa E, Bourgeois B, Biederman J. Comparing stimulant effects in youth with ADHD symptoms and epilepsy. Epilepsy & Behavior 2014, 36: 102-107. PMID: 24907495, PMCID: PMC4109643, DOI: 10.1016/j.yebeh.2014.04.026.Peer-Reviewed Original ResearchConceptsSeizure freedomADHD symptomsCGI improvement scoreImproved treatment outcomesHigh response rateUse of methylphenidateStart of trialMedication trialsMedical recordsUncontrolled designTreatment outcomesTreatment responseStimulant treatmentStimulant effectsPatientsResponse rateSeizuresMethylphenidateAmphetamine preparationsEmotional labilityBaseline frequencyEpilepsyAdverse effectsSymptomsTrials
2011
A survey of Autism knowledge and attitudes among the healthcare professionals in Lahore, Pakistan
Imran N, Chaudry MR, Azeem MW, Bhatti MR, Choudhary ZI, Cheema MA. A survey of Autism knowledge and attitudes among the healthcare professionals in Lahore, Pakistan. BMC Pediatrics 2011, 11: 107. PMID: 22107951, PMCID: PMC3250946, DOI: 10.1186/1471-2431-11-107.Peer-Reviewed Original ResearchConceptsAutistic disorderDSM-IV-TR criteriaTreatment of autismIV-TR diagnostic criteriaFuture awareness campaignsAutism knowledgeEmotional featuresHealthcare professionalsAutismProfessional groupsCurrent professionalsOutdated beliefsClinical implicationsMultiple settingsBeliefsHealth professionalsDisordersProfessionalsTR criteriaTimely referralMean ageResultsTwo hundredDiagnostic criteriaDemographic informationEarly detectionEffectiveness of Six Core Strategies Based on Trauma Informed Care in Reducing Seclusions and Restraints at a Child and Adolescent Psychiatric Hospital
Azeem MW, Aujla A, Rammerth M, Binsfeld G, Jones RB. Effectiveness of Six Core Strategies Based on Trauma Informed Care in Reducing Seclusions and Restraints at a Child and Adolescent Psychiatric Hospital. Journal Of Child And Adolescent Psychiatric Nursing 2011, 24: 11-15. PMID: 21272110, DOI: 10.1111/j.1744-6171.2010.00262.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent Health ServicesBehavior ControlChildChild Health ServicesDiagnostic and Statistical Manual of Mental DisordersDocumentationEthnicityFemaleHospitals, PsychiatricHumansKnowledge of Results, PsychologicalLeadershipMaleMental DisordersMental Health ServicesOrganizational InnovationRestraint, PhysicalRetrospective StudiesSocial IsolationStaff DevelopmentConceptsTrauma-Informed CareSeclusion/restraintInformed careMonths of studyHospitalized youthType of admissionLength of stayNumber of seclusionsNumber of admissionsUse of seclusionAdolescent psychiatric hospitalDisruptive behavior disordersRestraint episodesMajor diagnosesMedical recordsMore episodesHundred fiftyMood disordersPsychiatric diagnosisPsychiatric hospitalHospital staffBehavior disorderReducing SeclusionCarePatients
2005
Weight Loss and Anorexia With Quetiapine
Khawaja IS, Azeem MW, Ebrahim A. Weight Loss and Anorexia With Quetiapine. Psychiatric Services 2005, 56: 490-490. PMID: 15812105, DOI: 10.1176/appi.ps.56.4.490.Peer-Reviewed Original Research