1999
Activating Phosphorylation of the Kin28p Subunit of Yeast TFIIH by Cak1p
Kimmelman J, Kaldis P, Hengartner C, Laff G, Koh S, Young R, Solomon M. Activating Phosphorylation of the Kin28p Subunit of Yeast TFIIH by Cak1p. Molecular And Cellular Biology 1999, 19: 4774-4787. PMID: 10373527, PMCID: PMC84276, DOI: 10.1128/mcb.19.7.4774.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell CycleCyclin-Dependent Kinase-Activating KinaseCyclin-Dependent KinasesEnzyme ActivationPhosphorylationPoint MutationProtein Serine-Threonine KinasesRabbitsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTATA-Binding Protein Associated FactorsThreonineTranscription Factor TFIIDTranscription Factor TFIIHTranscription FactorsTranscription Factors, TFIIConceptsKinase activityGeneral transcription factor TFIIHTranscription factor TFIIHCTD kinase activityRNA polymerase IICell cycle CDKsCyclin-dependent kinasesPrevious biochemical observationsYeast TFIIHPolymerase IIActivating PhosphorylationLarge subunitCak1pCatalytic subunitKinase subunitTerminal domainTFIIHConditional alleleCell cyclePhosphorylationCAKSubunitsCDKMO15Kinase
1994
p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest.
Polyak K, Kato J, Solomon M, Sherr C, Massague J, Roberts J, Koff A. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes & Development 1994, 8: 9-22. PMID: 8288131, DOI: 10.1101/gad.8.1.9.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCDC2-CDC28 KinasesCell CommunicationCell CycleCell LineCyclin-Dependent Kinase 2Cyclin-Dependent Kinase-Activating KinaseCyclin-Dependent KinasesCyclinsMinkProtein Kinase InhibitorsProtein KinasesProtein Serine-Threonine KinasesProteinsProtein-Tyrosine KinasesSignal TransductionTransforming Growth Factor betaConceptsCdk2 complexesCyclin ECyclin D2-Cdk4 complexesCyclin-Cdk inhibitorCell-cell contactGrowth inhibitory signalsCell cycle arrestCatalytic subunitG1 progressionG1 cyclinsCell cycleCdk2 activationCycle arrestCDK2 inhibitionContact inhibitionCyclin E levelsActive complexAffinity chromatographyEpithelial cellsCDK2Inhibitory signalsCellsP27ComplexesActivation