2001
Selective T-cell subset ablation demonstrates a role for T1 and T2 cells in ongoing acute graft-versus-host disease: a model system for the reversal of disease
Liu J, Anderson B, Robert M, McNiff J, Emerson S, Shlomchik W, Shlomchik M. Selective T-cell subset ablation demonstrates a role for T1 and T2 cells in ongoing acute graft-versus-host disease: a model system for the reversal of disease. Blood 2001, 98: 3367-3375. PMID: 11719376, DOI: 10.1182/blood.v98.12.3367.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell DeathCytokinesDisease Models, AnimalFlow CytometryGanciclovirGraft vs Host DiseaseGraft vs Leukemia EffectHematopoiesisHematopoietic Stem CellsInterleukin-2Interleukin-4Lymphocyte SubsetsMaleMiceMice, TransgenicPromoter Regions, GeneticSimplexvirusSpleenThymidine KinaseThymus GlandT-LymphocytesWeight GainConceptsDonor T cellsT cellsT2 cellsGVHD reactionsHost diseaseInterleukin-2Herpes simplex virus thymidine kinase gene transductionAllogeneic stem cell transplantationCytokine-producing T cellsPrevention of GVHDStem cell transplantationReversal of diseaseT cell deletionLater time pointsAcute graftCytokine polarizationOngoing GVHDClinical GVHDAntibody infusionPeak diseaseClinical effectsCell transplantationIL-4 promoterGVHDDeficient mice
1994
Intragraft cytokine and cytotoxic T lymphocyte (CTL) specific protein expression as predictors of rat small intestine transplant rejection.
McDiarmid S, Farmer D, Kuniyoshi J, Robert M, Khadavi A, Shaked A, Busuttil R. Intragraft cytokine and cytotoxic T lymphocyte (CTL) specific protein expression as predictors of rat small intestine transplant rejection. Transplantation Proceedings 1994, 26: 1520-1. PMID: 8030018.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiomarkersCytokinesGraft RejectionInterferon-gammaInterleukin-2Interleukin-6Intestine, SmallMembrane GlycoproteinsPerforinPolymerase Chain ReactionPore Forming Cytotoxic ProteinsRatsRats, Inbred BNRats, Inbred LewReceptors, Interleukin-2RNA, MessengerSerine EndopeptidasesTime FactorsT-Lymphocytes, CytotoxicTransplantation, HomologousTransplantation, IsogeneicTumor Necrosis Factor-alpha