2015
Association of Cumulative Dose of Haloperidol With Next-Day Delirium in Older Medical ICU Patients*
Pisani MA, Araujo KL, Murphy TE. Association of Cumulative Dose of Haloperidol With Next-Day Delirium in Older Medical ICU Patients*. Critical Care Medicine 2015, 43: 996-1002. PMID: 25746748, PMCID: PMC4400211, DOI: 10.1097/ccm.0000000000000863.Peer-Reviewed Original ResearchConceptsMedical ICU patientsNext-day deliriumTime-dependent confoundingICU patientsCumulative doseMedical ICUNonintubated patientsOdds ratioConfusion Assessment MethodTreatment of deliriumDose of haloperidolAge 60 yearsEfficacy of haloperidolRoute of administrationAcademic medical centerImportant clinical covariatesICU stayIntubated patientsClinical covariatesObservational studyHigher oddsMedical CenterDeliriumPatientsHaloperidol
2014
The prevalence of undiagnosed diabetes mellitus and the association of baseline glycemic control on mortality in the intensive care unit: A prospective observational study
Hoang QN, Pisani MA, Inzucchi S, Hu B, Honiden S. The prevalence of undiagnosed diabetes mellitus and the association of baseline glycemic control on mortality in the intensive care unit: A prospective observational study. Journal Of Critical Care 2014, 29: 1052-1056. PMID: 25092614, DOI: 10.1016/j.jcrc.2014.06.007.Peer-Reviewed Original ResearchConceptsBaseline glycemic controlStress hyperglycemiaGlycemic controlUndiagnosed diabetesChronic Health Evaluation II scoreMedical intensive care unit patientsIntensive care unit patientsHemoglobin A1c levelsHistory of diabetesObservational cohort studyProspective observational studyUndiagnosed diabetes mellitusCare unit patientsIntensive care unitLower baseline HbA1cMultivariable logistic regressionSignificant differencesAcute PhysiologyHospital mortalityNondiabetic patientsBaseline HbA1cII scoreMICU patientsCohort studyCritical illness
2011
Critical Illness in HIV-Infected Patients in the Era of Combination Antiretroviral Therapy
Akgün KM, Huang L, Morris A, Justice AC, Pisani M, Crothers K. Critical Illness in HIV-Infected Patients in the Era of Combination Antiretroviral Therapy. Annals Of The American Thoracic Society 2011, 8: 301-307. PMID: 21653532, PMCID: PMC3132789, DOI: 10.1513/pats.201009-060wr.Peer-Reviewed Original ResearchConceptsCombination antiretroviral therapyAntiretroviral therapyICU admissionCritical illnessAdministration of ARTImpact of ARTProportion of deathsHIV eraOpportunistic infectionsHIVAIDS epidemicMore recent studiesIllnessPatientsAdmissionTherapyRecent studiesICUEtiologyInfectionMortalityIncidenceDiseaseAdministrationDisability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study
Vest MT, Murphy TE, Araujo K, Pisani MA. Disability in activities of daily living, depression, and quality of life among older medical ICU survivors: a prospective cohort study. Health And Quality Of Life Outcomes 2011, 9: 9. PMID: 21294911, PMCID: PMC3041645, DOI: 10.1186/1477-7525-9-9.Peer-Reviewed Original ResearchConceptsPost-ICU dischargeQuality of lifeYear post-ICU dischargeOlder ICU survivorsICU survivorsPhysical scoresICU dischargeADL disabilityMental scoresSF-12Daily livingMonths post-ICU admissionMonths post-ICU dischargeMean MCS scoreMedical ICU survivorsPost-ICU admissionSF12 physical scoreProspective cohort studyMean PCS scoreTreatment of depressionCross-sectional associationsMean physical scoreSF-12 dataImpaired ADLICU admission
2008
Delirium assessment in the intensive care unit: patient population matters
Pisani MA. Delirium assessment in the intensive care unit: patient population matters. Critical Care 2008, 12: 131. PMID: 18423059, PMCID: PMC2447584, DOI: 10.1186/cc6847.Peer-Reviewed Original Research
2003
Underrecognition of Preexisting Cognitive Impairment by Physicians in Older ICU Patients
Pisani MA, Redlich C, McNicoll L, Ely EW, Inouye SK. Underrecognition of Preexisting Cognitive Impairment by Physicians in Older ICU Patients. CHEST Journal 2003, 124: 2267-2274. PMID: 14665510, DOI: 10.1378/chest.124.6.2267.Peer-Reviewed Original ResearchConceptsOlder ICU patientsCognitive impairmentICU patientsPhysician recognitionUrban university teaching hospitalCross-sectional comparative studyBlessed Dementia Rating ScalePreexisting Cognitive ImpairmentIndependent risk factorMedical record abstractionUniversity Teaching HospitalCognitive impairment increasesDementia Rating ScaleMajority of casesMedical ICUPatient factorsRecord abstractionICU physiciansIntensive carePhysician interviewsRisk factorsTeaching hospitalSerious illnessICUInformant Questionnaire