2024
rTMS effects on urges and severity of tobacco use disorder operate independently of a retrieval-extinction component and involve frontal-striatal pathways
Li S, Ma X, Chen H, Wang M, Zheng Y, Yang B, Ni H, Potenza M, Dong G. rTMS effects on urges and severity of tobacco use disorder operate independently of a retrieval-extinction component and involve frontal-striatal pathways. Journal Of Affective Disorders 2024, 349: 21-31. PMID: 38190858, DOI: 10.1016/j.jad.2024.01.048.Peer-Reviewed Original ResearchDorsolateral prefrontal cortexRepetitive transcranial magnetic stimulationSmoking cravingFunctional connectivityTobacco use disorderBrain regionsRetrieval-extinction procedureLeft dorsolateral prefrontal cortexSimilar neural correlatesFrontal-striatal pathwaysStandard repetitive transcranial magnetic stimulationUse disordersMedial frontal gyrusIncreased functional connectivitySham repetitive transcranial magnetic stimulationExecutive controlSmoking cuesNeural correlatesTranscranial magnetic stimulationBrain responsesFrontal gyrusGreater activationLess activationSmoking urgesBilateral insula
2023
Validation of the Thai Assessment of Criteria for Specific Internet-use Disorders (ACSID-11) among young adults
Yang Y, Su J, Pimsen A, Chen J, Potenza M, Pakpour A, Chen J, Poon W, Nurmala I, Ruckwongpatr K, Lin C. Validation of the Thai Assessment of Criteria for Specific Internet-use Disorders (ACSID-11) among young adults. BMC Psychiatry 2023, 23: 819. PMID: 37940885, PMCID: PMC10633967, DOI: 10.1186/s12888-023-05210-z.Peer-Reviewed Original ResearchPrevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling Among Low-Income U.S. Veterans: Results from the National Veteran Homeless and Other Poverty Experiences (NV‐HOPE) Study
Stefanovics E, Potenza M, Tsai J. Prevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling Among Low-Income U.S. Veterans: Results from the National Veteran Homeless and Other Poverty Experiences (NV‐HOPE) Study. Journal Of Gambling Studies 2023, 40: 915-935. PMID: 37751035, DOI: 10.1007/s10899-023-10257-4.Peer-Reviewed Original ResearchU.S. veteransSubstance useMental illnessDrug use disordersPoor physical functioningLogistic regression analysisNon-white veteransChi-square testU.S. military veteransClinical characteristicsDevelopment of interventionsAdjusted associationsPhysical functioningRoutine screeningClinical measuresCurrent prevalenceUse disordersRecreational gamblingLifetime historyGreater symptomsVulnerable subpopulationsPrevalenceDiagnostic group differences and exploratory sex differences in intrinsic connectivity during fMRI Stroop in individuals with and without cocaine use disorder
Zakiniaeiz Y, Lacadie C, Macdonald-Gagnon G, DeVito E, Potenza M. Diagnostic group differences and exploratory sex differences in intrinsic connectivity during fMRI Stroop in individuals with and without cocaine use disorder. Drug And Alcohol Dependence 2023, 251: 110962. PMID: 37716288, PMCID: PMC10557108, DOI: 10.1016/j.drugalcdep.2023.110962.Peer-Reviewed Original ResearchConceptsCocaine use disorderCognitive controlStroop performanceIntrinsic connectivityStroop task performanceFMRI Stroop taskDiagnostic groupsUse disordersDiagnostic group differencesMain effectHealthy comparison subjectsStroop effectStroop taskBehavioral resultsTask performanceFrontal gyrusIntrinsic connectivity distributionPrefrontal cortexAuditory areasGroup differencesBrain connectivityCingulate gyrusStroopBehavioral differencesHC groupNeural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders
Mestre-Bach G, Potenza M. Neural mechanisms linked to treatment outcomes and recovery in substance-related and addictive disorders. Dialogues In Clinical Neuroscience 2023, 25: 75-91. PMID: 37594217, PMCID: PMC10444012, DOI: 10.1080/19585969.2023.2242359.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsNeural mechanismsAddictive disordersPotential neural mechanismsTreatment development effortsInternet gaming disorderBrain processesSubstance use disordersAdvanced analytic approachesGaming disorderImpulse controlTreatment developmentUse disordersPsychiatric conditionsExtant dataTreatment utilityAddictionDisordersAnalytic approachTreatment outcomesNarrative reviewIntervention administrationMedication challengePresent reviewMain modelsContextProblematic smartphone use and two types of problematic use of the internet and self-stigma among people with substance use disorders
Chang C, Chen J, Huang S, Potenza M, Su J, Chang K, Pakpour A, Lin C. Problematic smartphone use and two types of problematic use of the internet and self-stigma among people with substance use disorders. Addictive Behaviors 2023, 147: 107807. PMID: 37542974, DOI: 10.1016/j.addbeh.2023.107807.Peer-Reviewed Original ResearchConceptsProblematic smartphone useSubstance use disordersCognition-Execution (I-PACE) modelI-PACE modelSmartphone useProblematic useUse disordersPROCESS macro Model 4Person-AffectMediation modelCross-sectional designMediation analysisLongitudinal studyPeopleDisordersRelationshipPsychiatric centerFindingsParticipantsHayesModel 4ContextDiscriminating cocaine use from other sympathomimetics using wearable electrocardiographic (ECG) sensors
Angarita G, Pittman B, Nararajan A, Mayerson T, Parate A, Marlin B, Gueorguieva R, Potenza M, Ganesan D, Malison R. Discriminating cocaine use from other sympathomimetics using wearable electrocardiographic (ECG) sensors. Drug And Alcohol Dependence 2023, 250: 110898. PMID: 37523916, PMCID: PMC10905422, DOI: 10.1016/j.drugalcdep.2023.110898.Peer-Reviewed Original ResearchChanges in synaptic markers after administration of ketamine or psychedelics: a systematic scoping review
Zhornitsky S, Oliva H, Jayne L, Allsop A, Kaye A, Potenza M, Angarita G. Changes in synaptic markers after administration of ketamine or psychedelics: a systematic scoping review. Frontiers In Psychiatry 2023, 14: 1197890. PMID: 37435405, PMCID: PMC10331617, DOI: 10.3389/fpsyt.2023.1197890.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAdministration of ketamineSynaptic markersSubstance use disordersPrefrontal cortexSingle doseBasal conditionsStress-related reductionPsilocybin/psilocinVerbal memory performanceWeb of ScienceKetamine treatmentSystematic scoping reviewLysergic acid diethylamideSynaptic densityClinical studiesSynaptophysin 1PRISMA guidelinesSynapsin 1Use disordersPlace preferenceAbuse liabilitySynaptic changesKetaminePSD-95Study designDistinct neural networks predict cocaine versus cannabis treatment outcomes
Lichenstein S, Kohler R, Ye F, Potenza M, Kiluk B, Yip S. Distinct neural networks predict cocaine versus cannabis treatment outcomes. Molecular Psychiatry 2023, 28: 3365-3372. PMID: 37308679, PMCID: PMC10713861, DOI: 10.1038/s41380-023-02120-0.Peer-Reviewed Original ResearchConceptsConnectome-based predictive modelingCognitive behavior therapyCognitive behavioral therapySubstance use disordersCannabis abstinenceNeural mechanismsBehavior therapyDistinct neural networksComputer-based trainingCannabis use disorderFMRI scanningNeural predictorsStudy 1Study 2Treatment outcomesContingency managementPrior workComparison subjectsNetwork strengthUse disordersNovel treatment targetsAbstinenceIndependent samplesCocaine abstinenceTreatment respondersRelationships Between Impulsivity, Methamphetamine use Disorder and Gambling Disorder
Wang Y, Zuo J, Hao W, Wu L, Liu F, Wang Q, He L, Peng P, Zhou Y, Li M, Yang Q, Wang X, Liu T, Potenza M. Relationships Between Impulsivity, Methamphetamine use Disorder and Gambling Disorder. Journal Of Gambling Studies 2023, 39: 1635-1650. PMID: 36973505, DOI: 10.1007/s10899-023-10201-6.Peer-Reviewed Original ResearchConceptsMethamphetamine use disorderUse disordersMethamphetamine usePotential risk factorsDrug use characteristicsGambling disorderFirst sexual activityClinical characteristicsClinical featuresDrug rehabilitation centersRisk factorsHigh prevalenceDichotomous logistic regressionIndependent sample t-testRehabilitation centerCompulsory drug rehabilitation centerNon-planning impulsivityLogistic regressionSample t-testPrevalenceDisordersSexual activityBarratt Impulsiveness Scale-11T-testFamily membersSex-specific risk and resilience correlates of suicidal ideation in U.S. military veterans
Stefanovics E, Potenza M, Tsai J, Nichter B, Pietrzak R. Sex-specific risk and resilience correlates of suicidal ideation in U.S. military veterans. Journal Of Affective Disorders 2023, 328: 303-311. PMID: 36775254, DOI: 10.1016/j.jad.2023.02.025.Peer-Reviewed Original ResearchConceptsSuicidal ideationMale veteransFemale veteransU.S. military veteransRisk factorsGender-specific risk factorsPrevalence of SISex-specific riskMilitary veteransDifferent risk factorsAlcohol use disorderLow psychological resilienceMultivariable analysisNational HealthRepresentative sampleUse disordersU.S. veteransVeterans StudySuicide preventionTreatment effortsVeteransLow purposeStrongest correlatePrevalenceIdeationKey implementation factors in telemedicine-delivered medications for opioid use disorder: a scoping review informed by normalisation process theory
Teck J, Zlatkute G, Perez A, Dritschel H, Ghosh A, Potenza M, Ambekar A, Ekhtiari H, Stein D, Khazaal Y, Arunogiri S, Torrens M, Ferri M, Galea-Singer S, Baldacchino A. Key implementation factors in telemedicine-delivered medications for opioid use disorder: a scoping review informed by normalisation process theory. The Lancet Psychiatry 2023, 10: 50-64. PMID: 36526346, DOI: 10.1016/s2215-0366(22)00374-1.Peer-Reviewed Original ResearchConceptsNormalisation Process TheoryOpioid use disorderUse disordersCurrent evidence baseHealth care interventionsEnglish-language databasesClinical contactComplex health care interventionsHealth systemEvidence baseMedicationsCOVID-19 pandemicPeer-reviewed articlesNPT constructsKey implementation factorsPotential wideningDisordersCognitive participationStandard practiceThematic analysisReflexive monitoringReviewImplementation factorsTelehealth innovationMOUD
2022
Temporal associations between depressive features and self-stigma in people with substance use disorders related to heroin, amphetamine, and alcohol use: a cross-lagged analysis
Saffari M, Chang K, Chen J, Chang C, Chen I, Huang S, Liu C, Lin C, Potenza M. Temporal associations between depressive features and self-stigma in people with substance use disorders related to heroin, amphetamine, and alcohol use: a cross-lagged analysis. BMC Psychiatry 2022, 22: 815. PMID: 36544132, PMCID: PMC9768939, DOI: 10.1186/s12888-022-04468-z.Peer-Reviewed Original ResearchConceptsSubstance use disordersFeatures of depressionUse disordersDepression Anxiety Stress ScaleCross-lagged analysisCross-lagged associationsCross-lagged modelsAnxiety Stress ScaleGood fit indicesSubstance use concernsStructural equation modelingSelf-Stigma ScaleDepressive featuresMental health problemsLongitudinal relationshipStress ScaleEquation modelingSubstance useDirection of associationAlcohol useFit indicesUse concernsSocial relationshipsTemporal associationUnacceptable behaviorAre Signals Regulating Energy Homeostasis Related to Neuropsychological and Clinical Features of Gambling Disorder? A Case–Control Study
Etxandi M, Baenas I, Mora-Maltas B, Granero R, Fernández-Aranda F, Tovar S, Solé-Morata N, Lucas I, Casado S, Gómez-Peña M, Moragas L, del Pino-Gutiérrez A, Codina E, Valenciano-Mendoza E, Potenza M, Diéguez C, Jiménez-Murcia S. Are Signals Regulating Energy Homeostasis Related to Neuropsychological and Clinical Features of Gambling Disorder? A Case–Control Study. Nutrients 2022, 14: 5084. PMID: 36501114, PMCID: PMC9736671, DOI: 10.3390/nu14235084.Peer-Reviewed Original ResearchConceptsGambling disorderSemi-structured clinical interviewHigher impulsivity levelsBad psychological stateDysfunctional personality profileHigher cognitive impairmentGd presenceCognitive flexibilityNeuropsychological factorsSubstance use disordersDecision-making strategiesCognitive dimensionsImpulsivity levelsPsychological statePsychometric batteryVulnerability pathwaysHealthy controlsPersonality profilesBody mass indexCognitive impairmentClinical InterviewUse disordersGD groupPresent studyEnergy homeostasisPrevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling in a National Sample of U.S. Military Veterans
Stefanovics E, Potenza M, Tsai J, Pietrzak R. Prevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling in a National Sample of U.S. Military Veterans. Journal Of Gambling Studies 2022, 39: 1077-1097. PMID: 36378356, DOI: 10.1007/s10899-022-10165-z.Peer-Reviewed Original ResearchConceptsCurrent psychiatric diagnosisU.S. military veteransUse disordersPsychiatric diagnosisMilitary veteransU.S. veteransDrug use disordersMental health treatmentSubstance use disordersChi-square testClinical characteristicsTrauma burdenNational HealthAdjusted associationsRoutine screeningClinical measuresRecreational gamblingCurrent prevalenceMale veteransHealth treatmentHigher household incomeSuicidal ideationVeterans StudyLogistic regressionExtensive involvementMechanistic Effects and Use of N-acetylcysteine in Substance Use Disorders
Greenberg N, Farhadi F, Kazer B, Potenza M, Angarita G. Mechanistic Effects and Use of N-acetylcysteine in Substance Use Disorders. Current Behavioral Neuroscience Reports 2022, 9: 124-143. DOI: 10.1007/s40473-022-00250-3.Peer-Reviewed Original ResearchSubstance use disordersN-acetylcysteineUse disordersEfficacy of NACTreatment of SUDsGlial glutamate transporter-1Glutamate transporter 1Drug-seeking behaviorCue-induced reinstatementNAC useAdjunctive useClinical studiesGlutamate homeostasisGlutamate signalingNeurobiological effectsClinical approachRelapse behaviorSubcortical regionsSynaptic plasticityFunctional connectivity networksPrefrontal cortexBehavioral interventionsTransporter 1Oxidative stressImpulsive behaviorGlutamatergic Agents for the Treatment of Cocaine Use Disorder
Hadizadeh H, Flores J, Mayerson T, Worhunsky P, Potenza M, Angarita G. Glutamatergic Agents for the Treatment of Cocaine Use Disorder. Current Behavioral Neuroscience Reports 2022, 9: 101-112. DOI: 10.1007/s40473-022-00252-1.Peer-Reviewed Original ResearchCocaine use disorderRoute of administrationGlutamatergic systemSafety profileNovel agentsUse disordersMetabotropic glutamate receptor 5 antagonistNewer beta-lactam agentsAMPA/kainate receptorsTreatment of CUDBeta-lactam agentsGood safety profileMetabotropic glutamate receptorsPromising preclinical dataReceptors/transportersChronic cocaine useGLT-1 transporterBeta-lactam antibioticsOngoing trialsPreclinical supportGlutamatergic agentsGlutamate neurotransmissionPreclinical dataClinical trialsGlutamate receptorsNovel Pharmacological Agents for the Treatment of Cocaine Use Disorder
Hadizadeh H, Flores J, Nunes E, Mayerson T, Potenza M, Angarita G. Novel Pharmacological Agents for the Treatment of Cocaine Use Disorder. Current Behavioral Neuroscience Reports 2022, 9: 27-46. DOI: 10.1007/s40473-022-00246-z.Peer-Reviewed Original ResearchCocaine use disorderNovel pharmacological agentsUse disordersCocaine vaccinePharmacological agentsClinical supportNarrative reviewAlpha-adrenergic antagonistKappa-opioid receptorsCorticotropin-releasing factorCentral nervous systemPurpose of reviewClinical evidenceGlutamatergic agentsSerotonergic agentsCholinergic agentsOrexin antagonistsNeurobiological targetsDopamine pathwayArousal pathwayNervous systemExtension studyPromising agentCapacity of cocaineDisordersComparisons of psychological distress and self-stigma among three types of substance use disorders receiving treatment-as-usual approaches: real-world data from a 9-month longitudinal study
Chang K, Chen H, Huang S, Chen J, Potenza M, Pakpour A, Lin C. Comparisons of psychological distress and self-stigma among three types of substance use disorders receiving treatment-as-usual approaches: real-world data from a 9-month longitudinal study. Therapeutic Advances In Chronic Disease 2022, 13: 20406223221140393. PMID: 36483780, PMCID: PMC9723802, DOI: 10.1177/20406223221140393.Peer-Reviewed Original ResearchSubstance use disordersPsychological distressAlcohol use disorderUse disordersLongitudinal designAmphetamine use disorderSelf-Stigma ScaleSelf-stigma levelTime 1Time 2Type of SUDStress ScaleGroup differencesControl conditionSubstance useDistressLongitudinal studyOutpatient psychiatric centersEquation modelHigh levelsTime 4DisordersDropout rateConvenience samplingPeople
2021
A Global Survey on Changes in the Supply, Price, and Use of Illicit Drugs and Alcohol, and Related Complications During the 2020 COVID-19 Pandemic
Farhoudian A, Radfar SR, Ardabili H, Rafei P, Ebrahimi M, Zonoozi A, De Jong CAJ, Vahidi M, Yunesian M, Kouimtsidis C, Arunogiri S, Hansen H, Brady KT, Consortium I, Abagiu A, Abouna F, Ahmed M, Al-ansari B, Abu Al-khair F, Almaqbali M, Ambekar A, Arya S, Asebikan V, Ayasreh M, Basu D, Benmebarek Z, Bhad R, Blaise M, Bonnet N, Brasch J, Broers B, Busse A, Butner J, Camilleri M, Campello G, Carra G, Celic I, Chalabianloo F, Chaturvedi A, de Jesús Eduardo Noyola Cherpitel J, Clark K, Cyders M, de Bernardis E, Deilamizade A, Derry J, Dhagudu N, Dolezalova P, Dom G, Dunlop A, Elhabiby M, Elkholy H, Essien N, Farah G, Ferri M, Floros G, Friedman C, Fuderanan C, Gerra G, Ghosh A, Gogia M, Grammatikopoulos I, Grandinetti P, Guirguis A, Gutnisky D, Haber P, Hassani-Abharian P, Hooshyari Z, Ibrahim I, Ieong H, Indradewi R, Iskandar S, Isra T, Jain S, James S, Javadi S, Joe K, Jokubonis D, Jovanova A, Kamal R, Kantchelov A, Kathiresan P, Katzman G, Kawale P, Kern A, Kessler F, Kim S, Kimball A, Kljucevic Z, Kurniasanti K, Lev R, Lee H, Lengvenyte A, Lev-ran S, Mabelya G, Mahi M, Maphisa J, Maremmani I, Masferrer L, Massah O, McCambridge O, McGovern G, Min A, Moghanibashi-Mansourieh A, Mora-Rios J, Mudalige I, Mukherjee D, Munira P, Myers B, N. J, Narasimha V, Ndionuka N, Nejatisafa A, Niaz K, Nizami A, Nuijens J, Orsolini L, Oum V, Oyemade A, Palavra I, Pant S, Paredes J, Peyron E, Quirós R, Qurishi R, Rafiq N, Rao R, Ratta-apha W, Raymond K, Reimer J, Renaldo E, Rezapour T, Robertson J, Roncero C, Roub F, Rubenstein E, Rupp C, Saenz E, Salehi M, Samartzis L, Sarubbo L, Segrec N, Shah B, Shen H, Shirasaka T, Shoptaw S, Sintango F, Sosa V, Subata E, Sztycberg N, Taghizadeh F, Teck J, Tjagvad C, Torrens M, Twala J, Vadivel R, Volpicelli J, Weijs J, Wintoniw S, Wittayanookulluk A, Wojnar M, Yasir S, Yitayih Y, Zhao M, Potenza M, Baldacchino A, Ekhtiari H. A Global Survey on Changes in the Supply, Price, and Use of Illicit Drugs and Alcohol, and Related Complications During the 2020 COVID-19 Pandemic. Frontiers In Psychiatry 2021, 12: 646206. PMID: 34421664, PMCID: PMC8377291, DOI: 10.3389/fpsyt.2021.646206.Peer-Reviewed Original ResearchSubstance use disordersRelated complicationsCOVID-19 pandemicComplications of alcoholSubstance use patternsCross-sectional surveyCurrent pandemicUse of amphetaminesHypnotic usePrescription opioidsEpidemiologic studiesUse disordersMedicine NetworkComplicationsVulnerable populationsMedicine professionalsDrug supplyDrugsIllicit drugsPossible downstream effectsCOVID-19International SocietyDownstream effectsUse patternsPandemic