1999
Quantitative detection of Borrelia burgdorferi with a microtiter-based competitive polymerase chain reaction assay
Germer J, Ryckmann B, Moro M, Hofmeister E, Barthold S, Bockenstedt L, Persing D. Quantitative detection of Borrelia burgdorferi with a microtiter-based competitive polymerase chain reaction assay. Molecular Diagnosis 1999, 4: 185-193. PMID: 10553019, DOI: 10.1016/s1084-8592(99)80022-8.Peer-Reviewed Original ResearchConceptsLyme disease pathogenesisPolymerase chain reactionDisease pathogenesisBALB/c miceAvailable enzyme-linked immunosorbentB. burgdorferi flagellin geneChain reactionQuantitative competitive polymerase chain reactionEnzyme-linked immunosorbentCompetitive polymerase chain reactionImmunologic componentsInfectious burdenC miceInflammatory processC3H miceMurine modelAnimal modelsTissue weightTissue burdenLyme diseaseTarget tissuesSpecific target tissuesBorrelia burgdorferiDetection kitCompetitive internal standard
1998
Modulation of Murine Lyme Borreliosis by Interruption of the B7/CD28 T-Cell Costimulatory Pathway
Shanafelt M, Kang I, Barthold S, Bockenstedt L. Modulation of Murine Lyme Borreliosis by Interruption of the B7/CD28 T-Cell Costimulatory Pathway. Infection And Immunity 1998, 66: 266-271. PMID: 9423867, PMCID: PMC107886, DOI: 10.1128/iai.66.1.266-271.1998.Peer-Reviewed Original ResearchAbataceptAnimalsAntibodies, BacterialAntibodies, BlockingAntigens, CDAntigens, DifferentiationArthritis, InfectiousB7-1 AntigenB7-2 AntigenCD28 AntigensCTLA-4 AntigenFemaleImmunoconjugatesImmunoglobulin GInterferon-gammaInterleukin-4Lyme DiseaseLymphocyte ActivationMembrane GlycoproteinsMiceMice, Inbred BALB CSpecific Pathogen-Free OrganismsTh1 CellsTh2 CellsUp-Regulation