2008
Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma
Choi YJ, M Pinto M, Hao L, K Riba A. Interobserver variability and aberrant E-cadherin immunostaining of lobular neoplasia and infiltrating lobular carcinoma. Modern Pathology 2008, 21: 1224-1237. PMID: 18587329, DOI: 10.1038/modpathol.2008.106.Peer-Reviewed Original ResearchConceptsE-cadherin stainingLobular carcinomaLobular neoplasiaDuct lesionsDuct carcinomaPrevious diagnosisBreast lesionsMorphologic diagnosisInterobserver variabilityDifferent antibodiesE-cadherinImportant therapeutic implicationsParaffin-embedded sectionsLoss of stainingE-cadherin staining patternDuctal neoplasiaDuctal lesionsHistologic featuresLobular lesionsHistology diagnosisSurgical pathologistsImmunohistochemistry techniquesTherapeutic implicationsBlinded mannerCarcinoma
2002
Murine model of gastrointestinal ischemia associated with complement-dependent injury
Zhao H, Montalto MC, Pfeiffer KJ, Hao L, Stahl GL. Murine model of gastrointestinal ischemia associated with complement-dependent injury. Journal Of Applied Physiology 2002, 93: 338-345. PMID: 12070223, DOI: 10.1152/japplphysiol.00159.2002.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsColoring AgentsComplement C5Complement System ProteinsDigestive SystemGastrointestinal DiseasesImmunohistochemistryIntercellular Adhesion Molecule-1IntestinesL-Lactate DehydrogenaseLungMaleMiceMice, Inbred C57BLMice, KnockoutPeroxidaseRegional Blood FlowReperfusion InjuryReproducibility of ResultsReverse Transcriptase Polymerase Chain ReactionConceptsRemote tissue injuryTissue injuryGastrointestinal ischemiaMurine modelComplement-mediated tissue injuryIntercellular adhesion molecule-1 mRNAAnti-C5 treatmentComplement-dependent injuryInflammatory protein-2 mRNAIschemia-reperfusion injuryAttenuates tissue injuryNew murine modelC5 monoclonal antibodyNeutrophil accumulationNeutrophil infiltrationNeutrophil recruitmentProtein-2 mRNAChemokine expressionActivate complementInjuryAdherence moleculesComplement activationMonoclonal antibodiesProtein expressionLactate dehydrogenase