2023
Utility of promoter hypermethylation in malignant risk stratification of intraductal papillary mucinous neoplasms
Chhoda A, Sharma A, Sailo B, Tang H, Ruzgar N, Tan W, Ying L, Khatri R, Narayanan A, Mane S, De Kumar B, Wood L, Iacobuzio-Donahue C, Wolfgang C, Kunstman J, Salem R, Farrell J, Ahuja N. Utility of promoter hypermethylation in malignant risk stratification of intraductal papillary mucinous neoplasms. Clinical Epigenetics 2023, 15: 28. PMID: 36803844, PMCID: PMC9942382, DOI: 10.1186/s13148-023-01429-5.Peer-Reviewed Original ResearchConceptsPapillary mucinous neoplasmMalignant risk stratificationCACNA1G geneRisk stratificationMucinous neoplasmsBiomarker panelBackgroundIntraductal papillary mucinous neoplasmIntraductal papillary mucinous neoplasmEarly detectionPrevious case-control studyHigh-grade dysplasiaCase-control studyPancreatic cancer precursorsReceiver Operating Characteristic (ROC) curve analysisSignificant diagnostic challengeCross-sectional imagingCharacteristic curve analysisOperating Characteristic curve analysisG geneHigh diagnostic specificityPrior validation studiesSignificant procedural riskIPMN tissuesSurgical resectionAdvanced neoplasia
2019
Intraoperative Blood Pressure Lability Is Associated with Postoperative Hemorrhage after Uncomplicated Bariatric Surgery
Ying LD, Duffy AJ, Roberts KE, Ghiassi S, Hubbard MO, Nadzam GS. Intraoperative Blood Pressure Lability Is Associated with Postoperative Hemorrhage after Uncomplicated Bariatric Surgery. Obesity Surgery 2019, 29: 1990-1994. PMID: 30895505, DOI: 10.1007/s11695-019-03839-y.Peer-Reviewed Original ResearchConceptsPostoperative hemorrhageKetorolac administrationBariatric surgeryBlood pressurePressure labilityPre-operative blood pressureRetrospective case-control studyHigh-volume academic centersPerioperative medication administrationBariatric surgery patientsBlood pressure labilityCase-control studyType of procedurePostoperative bleedingRare complicationSurgery patientsMedication administrationAbdominal contentsAcademic centersHemorrhageLower MAPSurgeryAdministrationEnoxaparinPatients