2000
Activation of surfactant protein‐B transcription: Signaling through the SP‐A receptor utilizing the PI3 kinase pathway
Strayer D, Korutla L. Activation of surfactant protein‐B transcription: Signaling through the SP‐A receptor utilizing the PI3 kinase pathway. Journal Of Cellular Physiology 2000, 184: 229-238. PMID: 10867648, DOI: 10.1002/1097-4652(200008)184:2<229::aid-jcp11>3.0.co;2-x.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCells, CulturedDNA-Binding ProteinsFemaleGlycoproteinsHepatocyte Nuclear Factor 3-alphaLungNuclear ProteinsPhosphatidylinositol 3-KinasesPromoter Regions, GeneticProtein IsoformsProteolipidsPulmonary Surfactant-Associated Protein APulmonary Surfactant-Associated ProteinsPulmonary SurfactantsRatsReceptors, Cell SurfaceThyroid Nuclear Factor 1Transcription FactorsTranscription, GeneticConceptsSP-B promoterSP-B transcriptionPI3-kinaseHNF-3Consensus recognition elementSurfactant proteinsPI3-kinase pathwaySP-A receptorGel shift analysisCell transcriptional activityKinase localizationCellular functionsInteraction of SPTranscription factorsCell biologyNuclear localizationPlasma membraneKinase pathwayTranscriptional activityTranscriptionProteinSpCognate receptorsPromoterType II cells
1997
Surfactant protein-A receptor-mediated inhibition of calcium signaling in alveolar type II cells.
Strayer D, Korutla L, Thomas A. Surfactant protein-A receptor-mediated inhibition of calcium signaling in alveolar type II cells. Receptors & Signal Transduction 1997, 7: 111-20. PMID: 9392439.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine TriphosphateAnimalsBiological TransportCalciumIonomycinMalePhospholipidsProteolipidsPulmonary AlveoliPulmonary Surfactant-Associated Protein APulmonary Surfactant-Associated ProteinsPulmonary SurfactantsRatsRats, Sprague-DawleyReceptors, Cell SurfaceSignal TransductionThapsigarginConceptsReceptor-mediated inhibitionType II cellsII cellsSP-A receptorSurfactant proteinsType II alveolar cellsReceptor-mediated mechanismAlveolar type II cellsCell membrane receptorsQuantitative fluorescence microscopyAbsence of SPMembrane Ca channelsAction of SPFura-2Membrane receptorsCa storesBiphasic increaseIntracellular storesAlveolar cellsElicit Ca2Physiologic regulatorCalcium ionophoreCa channelsCell membraneIntracellular Ca