2016
Claudin-3 and claudin-19 partially restore native phenotype to ARPE-19 cells via effects on tight junctions and gene expression
Peng S, Wang SB, Singh D, Zhao PY, Davis K, Chen B, Adelman RA, Rizzolo LJ. Claudin-3 and claudin-19 partially restore native phenotype to ARPE-19 cells via effects on tight junctions and gene expression. Experimental Eye Research 2016, 151: 179-189. PMID: 27593915, DOI: 10.1016/j.exer.2016.08.021.Peer-Reviewed Original Research
2013
Engineering a Blood-Retinal Barrier With Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium: Transcriptome and Functional Analysis
Peng S, Gan G, Qiu C, Zhong M, An H, Adelman RA, Rizzolo LJ. Engineering a Blood-Retinal Barrier With Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium: Transcriptome and Functional Analysis. Stem Cells Translational Medicine 2013, 2: 534-544. PMID: 23734062, PMCID: PMC3697821, DOI: 10.5966/sctm.2012-0134.Peer-Reviewed Original ResearchConceptsRetinal pigment epitheliumBlood-retinal barrierHuman retinal pigment epitheliumPigment epitheliumHuman fetal retinal pigment epitheliumOuter blood-retinal barrierTight junctionsFetal retinal pigment epitheliumEmbryonic stem cell-derived retinal pigment epitheliumAdult retinal pigment epitheliumQuantitative reverse transcription polymerase chain reactionMaturation of hESCReverse transcription-polymerase chain reactionTranscription-polymerase chain reactionHuman embryonic stem cell-derived retinal pigment epitheliumStem cell-derived retinal pigment epitheliumRPE replacement therapyPanel of genesReplacement therapyAnimal modelsHuman embryonic stem cellsRetinal degenerationRPE functionSerum-free mediumHuman retina
2002
Claudin 5 Is Transiently Expressed During the Development of the Retinal Pigment Epithelium
Kojima S, Rahner C, Peng S, Rizzolo L. Claudin 5 Is Transiently Expressed During the Development of the Retinal Pigment Epithelium. The Journal Of Membrane Biology 2002, 186: 81-88. PMID: 11944085, DOI: 10.1007/s00232-001-0137-7.Peer-Reviewed Original ResearchConceptsReverse transcriptase-polymerase chain reactionRetinal pigment epitheliumClaudin-5Chick retinal pigment epitheliumPigment epitheliumTranscriptase-polymerase chain reactionEmbryonic day 14Tight junctionsSemiquantitative RT-PCRExpression of claudinsEmbryonic day 10Northern blottingNeural retinaDay 14Semi-quantitative RT-PCRDay 10Claudin-3RPE developmentPeak levelsDay 7 embryosChoroid layerPrimary culturesChain reactionEpitheliumBlotting