2020
RPE Polarity and Barrier Function
Rizzolo L. RPE Polarity and Barrier Function. 2020, 19-45. DOI: 10.1007/978-3-030-28384-1_2.ChaptersCell polarityEpithelial cell polarityPlasma membrane domainsTight junctionsBasolateral plasma membraneRPE polarityCellular processesMembrane domainsPlasma membraneMembrane transportersMembrane transportNeighboring cellsRPE phenotypeSemi-selective barrierProteinBarrier functionJunction proteinsRPE functionParacellular spaceOuter blood-retinal barrierVisual cycleTight junction proteinsTransepithelial electrical resistanceAsymmetric distributionDynamic interplay
1998
Polarization of the Na+, K+-ATPase in Epithelia Derived from the Neuroepithelium
Rizzolo L. Polarization of the Na+, K+-ATPase in Epithelia Derived from the Neuroepithelium. International Review Of Cytology 1998, 185: 195-235. PMID: 9750268, DOI: 10.1016/s0074-7696(08)60152-7.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsProper membrane domainDifferent sorting signalsPolarity mechanismsSorting signalsMembrane domainsMembrane proteinsCortical cytoskeletonCertain environmental stimuliFascinating groupMaintenance signalsApical membraneEnvironmental stimuliIon pumpsProteinBasolateral membraneATPaseYields insightsNeuroepitheliumMembraneCellsCytoskeletonEpitheliumRetinal pigment epitheliumSignalsPigment epithelium
1987
Nonpolarized secretion of truncated forms of the influenza hemagglutinin and the vesicular stomatitus virus G protein from MDCK cells.
Gonzalez A, Rizzolo L, Rindler M, Adesnik M, Sabatini D, Gottlieb T. Nonpolarized secretion of truncated forms of the influenza hemagglutinin and the vesicular stomatitus virus G protein from MDCK cells. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 3738-3742. PMID: 3035552, PMCID: PMC304951, DOI: 10.1073/pnas.84.11.3738.Peer-Reviewed Original ResearchConceptsApical plasma membrane domainMDCK cellsPlasma membrane domainsPolarity of secretionVirus G proteinViral glycoproteinsVesicular stomatitus virusMembrane anchoringCorresponding genesMembrane domainsCytoplasmic segmentNonpolarized fashionG proteinsEndogenous glycoproteinsApical surfaceProteinEpithelial cellsGlycoprotein GG glycoproteinGlycoproteinConfluent monolayersCellsInfluenza hemagglutininCDNAGenes
1986
Sorting and endocytosis of viral glycoproteins in transfected polarized epithelial cells.
Gottlieb T, Gonzalez A, Rizzolo L, Rindler M, Adesnik M, Sabatini D. Sorting and endocytosis of viral glycoproteins in transfected polarized epithelial cells. Journal Of Cell Biology 1986, 102: 1242-1255. PMID: 3007530, PMCID: PMC2114186, DOI: 10.1083/jcb.102.4.1242.Peer-Reviewed Original ResearchConceptsG proteinsCell surfaceVesicular stomatitis virusApical plasma membrane domainPlasma membrane domainsPlasma membrane proteinsCell surface domainsApical cell surfaceMadin-Darby canine kidney cellsG protein moleculesViral glycoproteinsLysosome-like vesiclesCanine kidney cellsProtein synthesis inhibitorMembrane domainsMembrane proteinsSurface domainsBasolateral domainEukaryotic expression plasmidTransfection experimentsExpression plasmidProteinPresence of chloroquineApical surfaceProtein molecules