Featured Publications
Dynamic structural equation modeling of the relationship between alcohol habit and drinking variability
DeMartini KS, Gueorguieva R, Taylor JR, Krishnan-Sarin S, Pearlson G, Krystal JH, O'Malley SS. Dynamic structural equation modeling of the relationship between alcohol habit and drinking variability. Drug And Alcohol Dependence 2021, 233: 109202. PMID: 35151022, PMCID: PMC10046111, DOI: 10.1016/j.drugalcdep.2021.109202.Peer-Reviewed Original ResearchMapping data‐driven individualized neurobehavioral phenotypes in heavy alcohol drinkers
DeMartini KS, Gueorguieva R, Pearlson G, Krishnan‐Sarin S, Anticevic A, Ji LJ, Krystal JH, O’Malley S. Mapping data‐driven individualized neurobehavioral phenotypes in heavy alcohol drinkers. Alcohol Clinical And Experimental Research 2021, 45: 841-853. PMID: 33605439, DOI: 10.1111/acer.14580.Peer-Reviewed Original ResearchConceptsConfirmatory factor analysisIncentive salienceNeurofunctional domainsAlcohol use disorderExecutive functionLatent factorsPhysical neglectSelf-report measuresChildhood emotional abuseUse disordersChildhood physical neglectEarly life stressSignificant predictorsMultiple significant predictorsMultiple causes modelCurrent AUDNegative emotionalityAddiction developmentEmotional abuseChildhood neglectFactor structureDrinking frequencySalienceCause modelFactor analysisText Messaging to Reduce Alcohol Relapse in Prelisting Liver Transplant Candidates: A Pilot Feasibility Study
DeMartini KS, Schilsky ML, Palmer A, Fehon DC, Zimbrean P, O'Malley SS, Lee HB, Toll BA. Text Messaging to Reduce Alcohol Relapse in Prelisting Liver Transplant Candidates: A Pilot Feasibility Study. Alcohol Clinical And Experimental Research 2018, 42: 761-769. PMID: 29498753, PMCID: PMC6438371, DOI: 10.1111/acer.13603.Peer-Reviewed Original ResearchConceptsAlcoholic liver diseaseLiver transplant candidatesLiver transplant patientsStandard careEfficacy outcomesTransplant patientsTransplant candidatesFeasibility outcomesTM participantsAlcohol interventionsClinical efficacy outcomesLiver transplantation programPreliminary efficacy outcomesPrimary feasibility outcomePilot feasibility trialPilot feasibility studyRelapse prevention interventionsBetter treatment outcomesLiver diseaseFeasibility trialUnited NetworkTransplantation programIntervention satisfactionTreatment outcomesAlcohol relapseSensitivity, specificity, and tolerability of the BACTrack Skyn compared to other alcohol monitoring approaches among young adults in a field‐based setting
Ash GI, Gueorguieva R, Barnett NP, Wang W, Robledo DS, DeMartini KS, Pittman B, Redeker NS, O’Malley S, Fucito LM. Sensitivity, specificity, and tolerability of the BACTrack Skyn compared to other alcohol monitoring approaches among young adults in a field‐based setting. Alcohol Clinical And Experimental Research 2022, 46: 783-796. PMID: 35567595, PMCID: PMC9179100, DOI: 10.1111/acer.14804.Peer-Reviewed Original Research
2022
Within‐ and between‐person effects of naltrexone on the subjective response to alcohol and craving: A daily diary investigation
Waddell JT, Corbin WR, MacKinnon DP, Leeman RF, DeMartini KS, Fucito LM, Kranzler HR, O’Malley S. Within‐ and between‐person effects of naltrexone on the subjective response to alcohol and craving: A daily diary investigation. Alcohol Clinical And Experimental Research 2022, 46: 477-491. PMID: 35076087, PMCID: PMC9679805, DOI: 10.1111/acer.14780.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DrinkingAlcoholismCravingDouble-Blind MethodEthanolHumansNaltrexoneNarcotic AntagonistsYoung AdultConceptsMedication dosageYoung adultsLight drinkingSubjective responsesSubjective effectsHeavy drinkingPlacebo-controlled studyEffect sizePerson effectsEffective treatmentNaltrexoneDrinking daysNaltrexone efficacySmall effect sizesDrinking levelsCravingDrinkingAdultsLaboratory-based studiesPillsMomentary assessmentEfficacyTreatment conditionsDrinking environmentsDaily diary data
2021
Effects of the Fyn kinase inhibitor saracatinib on ventral striatal activity during performance of an fMRI monetary incentive delay task in individuals family history positive or negative for alcohol use disorder. A pilot randomised trial
Patel KT, Stevens MC, Dunlap A, Gallagher A, O’Malley S, DeMartini K, Potenza MN, Krystal JH, Pearlson GD. Effects of the Fyn kinase inhibitor saracatinib on ventral striatal activity during performance of an fMRI monetary incentive delay task in individuals family history positive or negative for alcohol use disorder. A pilot randomised trial. Neuropsychopharmacology 2021, 47: 840-846. PMID: 34475522, PMCID: PMC8882177, DOI: 10.1038/s41386-021-01157-5.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DrinkingAlcoholismBenzodioxolesHumansMagnetic Resonance ImagingMotivationPilot ProjectsQuinazolinesRewardConceptsProtein tyrosine kinasesSrc regulationSrc familyProtein kinaseTyrosine kinaseFyn kinaseSrc inhibitorSrc/FynDependent pathwayKinaseNMDAR upregulationNMDAR functionNMDA receptorsRegulationSaracatinibGluN2B subunitGlutamate receptorsFynInhibitorsReceptorsSubunitsN-methyl-D-aspartate (NMDA) glutamate receptorsPrevious evidenceReward drinking and naltrexone treatment response among young adult heavy drinkers
Roos CR, Bold KW, Witkiewitz K, Leeman RF, DeMartini KS, Fucito LM, Corbin WR, Mann K, Kranzler HR, O'Malley SS. Reward drinking and naltrexone treatment response among young adult heavy drinkers. Addiction 2021, 116: 2360-2371. PMID: 33620746, PMCID: PMC8328878, DOI: 10.1111/add.15453.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlcohol DrinkingAlcoholismBlood Alcohol ContentFemaleHumansMaleNaltrexoneRewardYoung Adult
2020
Using Web-Based Social Media to Recruit Heavy-Drinking Young Adults for Sleep Intervention: Prospective Observational Study
Ash GI, Robledo DS, Ishii M, Pittman B, DeMartini KS, O'Malley SS, Redeker NS, Fucito LM. Using Web-Based Social Media to Recruit Heavy-Drinking Young Adults for Sleep Intervention: Prospective Observational Study. Journal Of Medical Internet Research 2020, 22: e17449. PMID: 32780027, PMCID: PMC7448185, DOI: 10.2196/17449.Peer-Reviewed Original ResearchConceptsAlcohol use disorderSleep interventionsSleep concernsYoung adultsAlcohol useWeb-based surveyBrief web-based surveyProspective observational studyHeavy-drinking young adultsYears of ageHigh response rateAlcohol prevention strategiesHeavy alcohol useAlcohol prevention programsHeavy drinking young adultsScreening eligibilityRisk factorsStudy enrolleesObservational studySleep programSleep problemsAlcohol screenerUse disordersPrevention strategiesResponse rateExamining the Relationship Between Self‐Reported Drinking and In‐Laboratory Drinking and Craving: Is There Concordance?
DeMartini KS, Pittman B, Krystal JH, O’Malley S, Krishnan‐Sarin S. Examining the Relationship Between Self‐Reported Drinking and In‐Laboratory Drinking and Craving: Is There Concordance? Alcohol Clinical And Experimental Research 2020, 44: 1151-1157. PMID: 32352581, PMCID: PMC10158572, DOI: 10.1111/acer.14329.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismCravingEthanolFemaleHumansLaboratoriesMaleRisk FactorsSelf ReportWorld Health OrganizationConceptsSelf-reported drinkingAlcohol cravingDrinking daysAlcohol consumptionDrinking paradigmHeavy drinking daysAlcohol use disorderSummary drinking measuresMaximum drinksPharmacotherapy studiesAdult heavy drinkersMedication administrationAverage drinksUse disordersHeavy drinkersAlcohol assessmentSignificant associationTotal drinksDrinking sessionDrinking indicesAdditional outcomesBehavioral interventionsLimited evidenceRisk classificationCraving
2018
The Self-Report Habit Index: Assessing habitual marijuana, alcohol, e-cigarette, and cigarette use
Morean ME, DeMartini KS, Foster D, Patock-Peckham J, Garrison KA, Corlett PR, Krystal JH, Krishan-Sarin S, O'Malley SS. The Self-Report Habit Index: Assessing habitual marijuana, alcohol, e-cigarette, and cigarette use. Drug And Alcohol Dependence 2018, 186: 207-214. PMID: 29609132, PMCID: PMC5912163, DOI: 10.1016/j.drugalcdep.2018.01.014.Peer-Reviewed Original ResearchA Test of Multisession Automatic Action Tendency Retraining to Reduce Alcohol Consumption Among Young Adults in the Context of a Human Laboratory Paradigm
Leeman RF, Nogueira C, Wiers RW, Cousijn J, Serafini K, DeMartini KS, Bargh JA, O'Malley SS. A Test of Multisession Automatic Action Tendency Retraining to Reduce Alcohol Consumption Among Young Adults in the Context of a Human Laboratory Paradigm. Alcohol Clinical And Experimental Research 2018, 42: 803-814. PMID: 29450895, PMCID: PMC5995797, DOI: 10.1111/acer.13613.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingChoice BehaviorEducationEthanolFemaleHumansMaleSelf AdministrationYoung AdultConceptsHuman laboratory paradigmLaboratory paradigmApproach tendenciesControl conditionYoung adultsYoung adult heavy drinkingAlcohol-approach tendenciesAutomatic action tendenciesAlcohol-related stimuliYoung adults' alcohol consumptionAlcohol consumptionHeavy drinking young adultsLaboratory-based measuresAlcohol drinking sessionsAction tendenciesYoung adults ages 21Individual differencesImportant public health concernSelf-administration behaviorAdults ages 21Adult alcohol consumptionPublic health concernOnly modest effectsExperimental manipulationImpaired controlReciprocal Variations in Sleep and Drinking Over Time Among Heavy-Drinking Young Adults
Fucito LM, Bold KW, Van Reen E, Redeker NS, O’Malley S, Hanrahan TH, DeMartini KS. Reciprocal Variations in Sleep and Drinking Over Time Among Heavy-Drinking Young Adults. Journal Of Psychopathology And Clinical Science 2018, 127: 92-103. PMID: 29172601, PMCID: PMC5785424, DOI: 10.1037/abn0000312.Peer-Reviewed Original Research
2016
Urgency traits moderate daily relations between affect and drinking to intoxication among young adults
Bold KW, Fucito LM, DeMartini KS, Leeman RF, Kranzler HR, Corbin WR, O’Malley S. Urgency traits moderate daily relations between affect and drinking to intoxication among young adults. Drug And Alcohol Dependence 2016, 170: 59-65. PMID: 27875802, PMCID: PMC5183550, DOI: 10.1016/j.drugalcdep.2016.10.035.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAffectAlcohol DrinkingAlcoholic IntoxicationDouble-Blind MethodFemaleHumansMaleMotivationNaltrexoneYoung AdultConceptsYoung adultsHeavy drinkingEffectiveness of naltrexoneBlood alcohol concentrationHeavy drinking young adultsBrief motivational interventionNaltrexone treatmentClinical trialsHazardous drinkingNaltrexoneSecondary analysisPlaceboTargeted interventionsAge 18Alcohol useIntoxicationLow urgencyAdultsMotivational interventionDrinkingTrait urgencyOddsInterventionCurrent studyRiskDaily Relations Among Affect, Urge, Targeted Naltrexone, and Alcohol Use in Young Adults
Bold KW, Fucito LM, Corbin WR, DeMartini KS, Leeman RF, Kranzler HR, O’Malley S. Daily Relations Among Affect, Urge, Targeted Naltrexone, and Alcohol Use in Young Adults. Experimental And Clinical Psychopharmacology 2016, 24: 367-375. PMID: 27690505, PMCID: PMC5111359, DOI: 10.1037/pha0000090.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAffectAlcohol DrinkingCounselingCuesDouble-Blind MethodFemaleHumansMaleNaltrexoneYoung AdultConceptsYoung adultsDouble-blind clinical trialHeavy drinkingSerious public health problemDose of medicationPublic health problemAlcohol-related interventionsTargeted naltrexoneNaltrexone groupOpioid antagonistRisk factorsClinical trialsFamily historyNaltrexone effectsGreater oddsAlcohol consumptionHealth problemsAlcohol dependenceSecondary analysisPlaceboNaltrexoneNaltrexone's abilityAdultsMedicationsDrinking
2015
Reduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety.
O'Malley SS, Corbin WR, Leeman RF, DeMartini KS, Fucito LM, Ikomi J, Romano DM, Wu R, Toll BA, Sher KJ, Gueorguieva R, Kranzler HR. Reduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety. The Journal Of Clinical Psychiatry 2015, 76: e207-13. PMID: 25742208, PMCID: PMC4442987, DOI: 10.4088/jcp.13m08934.Peer-Reviewed Original ResearchConceptsHeavy drinking daysBlood alcohol concentrationPercent days abstinentDrinking daysNumber of drinksYoung adultsDays abstinentPercent heavy drinking daysOutpatient research centerSafety of naltrexonePlacebo-controlled studySerious adverse eventsRisk-benefit ratioPercentage of daysAdverse eventsSecondary outcomesPrimary outcomeFrequency of drinkingOpioid antagonistAdult heavy drinkersAlcohol drinkingClinical trialsEvaluable samplesYoung adult heavy drinkersTreatment period
2014
A New Look at Risk-Taking: Using a Translational Approach to Examine Risk-Taking Behavior on the Balloon Analogue Risk Task
DeMartini KS, Leeman RF, Corbin WR, Toll BA, Fucito LM, Lejuez CW, O’Malley S. A New Look at Risk-Taking: Using a Translational Approach to Examine Risk-Taking Behavior on the Balloon Analogue Risk Task. Experimental And Clinical Psychopharmacology 2014, 22: 444-452. PMID: 25069012, PMCID: PMC4392709, DOI: 10.1037/a0037421.Peer-Reviewed Original ResearchPerceptions of Heavy-Drinking College Students About a Sleep and Alcohol Health Intervention
Fucito LM, DeMartini KS, Hanrahan TH, Whittemore R, Yaggi HK, Redeker NS. Perceptions of Heavy-Drinking College Students About a Sleep and Alcohol Health Intervention. Behavioral Sleep Medicine 2014, 13: 395-411. PMID: 24924956, PMCID: PMC4265000, DOI: 10.1080/15402002.2014.919919.Peer-Reviewed Original ResearchConceptsCollege studentsHeavy-drinking college studentsHeavy drinking college studentsPerception of sleepSleep-related impairmentSemistructured focus group interviewsWeb-based interventionPsychological characteristicsMixed-methods studySleep disturbancesQualitative investigationSleep latencyAlcohol interactionsFocus group interviewsSleepPerceptionFrequent drinkingSpecific contentParticipantsMethods studyFormat preferencesStudentsGroup interviewsInterventionHealth interventions
2013
Drinking Less and Drinking Smarter: Direct and Indirect Protective Strategies in Young Adults
DeMartini KS, Palmer RS, Leeman RF, Corbin WR, Toll BA, Fucito LM, O’Malley S. Drinking Less and Drinking Smarter: Direct and Indirect Protective Strategies in Young Adults. Psychology Of Addictive Behaviors 2013, 27: 615-626. PMID: 23088406, PMCID: PMC3869566, DOI: 10.1037/a0030475.Peer-Reviewed Original ResearchConceptsAlcohol-related consequencesClinical samplesYoung adult drinkingLow alcohol consumptionAdult drinkingPatient goalsYoung adult drinkersAlcohol consumptionProtective behavioral strategiesAlcohol useYoung adultsConfirmatory factor analysisProtective strategiesDrinking levelsLow drinking levelsAdult drinkersDrinkingDrinkersInterventionStrategies QuestionnaireCFA modelFactorsInterventions to Reduce Alcohol Use among HIV-Infected Individuals: A Review and Critique of the Literature
Brown J, DeMartini K, Sales J, Swartzendruber A, DiClemente R. Interventions to Reduce Alcohol Use among HIV-Infected Individuals: A Review and Critique of the Literature. Current HIV/AIDS Reports 2013, 10: 356-370. PMID: 23990322, PMCID: PMC3855569, DOI: 10.1007/s11904-013-0174-8.Peer-Reviewed Original ResearchConceptsAlcohol useAlcohol use outcomesIntervention efficacyUse outcomesAlcohol use disorderHealth risk behaviorsCore intervention componentsAlcohol abuseHIVTrial designUse disordersEfficacious interventionsRisk behaviorsIntervention componentsBehavioral interventionsPhysiological complicationsAlcohol frequencyDependence symptomsInterventionIntervention approachesEfficacious intervention approachesEfficacyOutcomesIndividualsComplicationsIdentification of trajectories of social network composition change and the relationship to alcohol consumption and norms
DeMartini KS, Prince MA, Carey KB. Identification of trajectories of social network composition change and the relationship to alcohol consumption and norms. Drug And Alcohol Dependence 2013, 132: 309-315. PMID: 23523132, PMCID: PMC3748204, DOI: 10.1016/j.drugalcdep.2013.02.020.Peer-Reviewed Original Research