Neural responses to reward valence and magnitude from pre- to early adolescence
Polack R, Mollick J, Keren H, Joormann J, Watts R. Neural responses to reward valence and magnitude from pre- to early adolescence. NeuroImage 2023, 275: 120166. PMID: 37178821, PMCID: PMC10311119, DOI: 10.1016/j.neuroimage.2023.120166.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingChildCorpus StriatumHumansMagnetic Resonance ImagingMotivationPrefrontal CortexRewardConceptsReward processingEarly adolescenceNeural responsesTrial typesMonetary incentive delay taskIncentive delay taskNeural reactivityNeural basisAdolescent developmentDelay taskIncentive valenceFunctional neuroanatomyNeural activationMotivational behaviorPreadolescent childrenReward circuitrySuccess feedbackAdolescenceDevelopmental changesValenceIndependent subsamplesStatus differencesBiological sexEffect sizeLarge sampleStructural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure
Harnett N, Fani N, Carter S, Sanchez L, Rowland G, Davie W, Guzman C, Lebois L, Ely T, van Rooij S, Seligowski A, Winters S, Grasser L, Musey P, Seamon M, House S, Beaudoin F, An X, Zeng D, Neylan T, Clifford G, Linnstaedt S, Germine L, Bollen K, Rauch S, Haran J, Storrow A, Lewandowski C, Hendry P, Sheikh S, Jones C, Punches B, Swor R, Hudak L, Pascual J, Harris E, Chang A, Pearson C, Peak D, Merchant R, Domeier R, Rathlev N, Bruce S, Miller M, Pietrzak R, Joormann J, Barch D, Pizzagalli D, Harte S, Elliott J, Kessler R, Koenen K, McLean S, Jovanovic T, Stevens J, Ressler K. Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure. Molecular Psychiatry 2023, 28: 2975-2984. PMID: 36725899, PMCID: PMC10615735, DOI: 10.1038/s41380-023-01971-x.Peer-Reviewed Original ResearchMeSH KeywordsAmygdalaFearGyrus CinguliHumansLongitudinal StudiesMagnetic Resonance ImagingPrefrontal CortexStress Disorders, Post-TraumaticConceptsPost-traumatic stress disorderAmygdala connectivityAmygdala reactivityTrauma exposurePrefrontal cortexPTSD symptomsDorsal anterior cingulate cortexAnterior cingulate cortexFunctional magnetic resonance imagingMagnetic resonance imagingGreater amygdala connectivityDorsolateral prefrontal cortexSymptoms 3Trauma outcomesSkin conductance levelCingulate cortexEthnic groupsEthnic disparitiesResonance imagingMultisite longitudinal studyStress disorderTwo weeksEthnic variabilityWhite individualsBlack participants