2019
Cradle-to-Gate Greenhouse Gas Emissions for Twenty Anesthetic Active Pharmaceutical Ingredients Based on Process Scale-Up and Process Design Calculations
Parvatker A, Tunceroglu H, Sherman J, Coish P, Anastas P, Zimmerman J, Eckelman M. Cradle-to-Gate Greenhouse Gas Emissions for Twenty Anesthetic Active Pharmaceutical Ingredients Based on Process Scale-Up and Process Design Calculations. ACS Sustainable Chemistry & Engineering 2019, 7: 6580-6591. DOI: 10.1021/acssuschemeng.8b05473.Peer-Reviewed Original ResearchPharmaceutical drugsActive pharmaceutical ingredientsChemical engineering methodsPharmaceutical intermediatesPharmaceutical ingredientsSynthesis stepChemical compoundsProcess design calculationsLow environmental impactStoichiometric calculationsCompoundsGate greenhouse gas emissionsGate GHG emissionsIntermediatesCalculationsEmissionComparative life cycle assessmentDrugs
2010
Toward molecular design for hazard reduction—fundamental relationships between chemical properties and toxicity
Voutchkova A, Ferris L, Zimmerman J, Anastas P. Toward molecular design for hazard reduction—fundamental relationships between chemical properties and toxicity. Tetrahedron 2010, 66: 1031-1039. DOI: 10.1016/j.tet.2009.11.002.Peer-Reviewed Original ResearchPhysical/chemical propertiesCommercial chemicalsChemical propertiesMolecular designChemical compoundsToxics Release InventoryCompoundsQikPropChemicalsChemical characteristicsPhysical propertiesPropertiesExcretion characteristicsEPA Toxics Release InventoryAdsorptionToxicity endpointsHuman toxicityTRI chemicalsRelease InventoryBioavailabilityToxicity