8. A CROSS-POPULATION GENOME-WIDE ASSOCIATION STUDY OF SLEEP DURATION
Austin-Zimmerman I, Levey D, Deak J, Galimberti M, Adhikari K, Zhou H, Di Forti M, Polimanti R, Stein M, Gelernter J. 8. A CROSS-POPULATION GENOME-WIDE ASSOCIATION STUDY OF SLEEP DURATION. European Neuropsychopharmacology 2023, 75: s60. DOI: 10.1016/j.euroneuro.2023.08.119.Peer-Reviewed Original ResearchSleep durationMillion Veteran ProgramLong sleepCoronary artery diseaseType 2 diabetesAdequate sleep durationShort sleep durationMajor depressive disorderLong sleep durationSleep duration dataPost-traumatic stress disorderGenome-wide association studiesMendelian randomisation analysisArtery diseaseDisturbed sleepDepressive disorderShort sleepRisk lociHealth outcomesSleep hoursCognitive functionSleepStress disorderRandomisation analysisMendelian randomisationGenome-wide association studies and cross-population meta-analyses investigating short and long sleep duration
Austin-Zimmerman I, Levey D, Giannakopoulou O, Deak J, Galimberti M, Adhikari K, Zhou H, Denaxas S, Irizar H, Kuchenbaecker K, McQuillin A, Concato J, Buysse D, Gaziano J, Gottlieb D, Polimanti R, Stein M, Bramon E, Gelernter J. Genome-wide association studies and cross-population meta-analyses investigating short and long sleep duration. Nature Communications 2023, 14: 6059. PMID: 37770476, PMCID: PMC10539313, DOI: 10.1038/s41467-023-41249-y.Peer-Reviewed Original ResearchConceptsAssociation studiesGenome-wide association studiesGenetic correlationsWide association studyLinkage disequilibrium scorePositive genetic correlationSleep traitsIndependent lociMillion Veteran ProgramTraitsAncestryUK BiobankVeteran ProgramMendelian randomisationLociHeritabilitySNPsPhenotypeEast AsiansSimilar patternCardiometabolic phenotypes