2024
Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Varthi A, Rubio D, Grauer J. Semaglutide utilization associated with reduced ninety-day postoperative complications following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024 PMID: 39491749, DOI: 10.1016/j.spinee.2024.10.011.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsAdverse eventsPostoperative complicationsT2DM patientsCurrent Procedural TerminologyElixhauser Comorbidity IndexED visitsLumbar fusionHospital readmissionEmergency departmentOdds of postoperative complicationsNinety-day postoperative complicationsImpact of semaglutideOdds of hospital readmissionMonths of surgeryRetrospective cohort studyPostoperative adverse eventsMinor adverse eventsType II diabetes mellitusRisk of type I errorDiagnosis of T2DMII diabetes mellitusYears of ageRisk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients
Ratnasamy P, Diatta F, Allam O, Kauke-Navarro M, Grauer J. Risk of Postoperative Complications After Total Hip and Total Knee Arthroplasty in Behcet Syndrome Patients. JAAOS Global Research And Reviews 2024, 8: e24.00040. PMID: 39392934, PMCID: PMC11469891, DOI: 10.5435/jaaosglobal-d-24-00040.Peer-Reviewed Original ResearchConceptsBehcet's syndromeAdverse eventsTotal knee arthroplastyMultivariate analysisRevision surgeryRisk of postoperative complicationsRisk of perioperative adverse eventsTotal hip arthroplastyLog-rank testElixhauser Comorbidity Index scoreRetrospective cohort studyMultisystem autoimmune disorderPostoperative adverse eventsPerioperative adverse eventsComorbidity Index scoreNational administrative databaseKnee arthroplastyTotal knee arthroplasty patientsPostoperative complicationsNo significant differencePatient ageAutoimmune disordersPerioperative managementSyndrome patientsCohort studyP31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy
Seddio A, Gouzoulis M, Smith-Voudouris J, Rubio D, Day W, Grauer J. P31. Testosterone replacement therapy associated with increased 90-day postoperative adverse events and 5-year reoperation following lumbar discectomy. The Spine Journal 2024, 24: s78. DOI: 10.1016/j.spinee.2024.06.052.Peer-Reviewed Original ResearchTestosterone replacement therapyAcute kidney injuryLumbar discectomyAdverse eventsMale patientsOdds ratioCurrent Procedural TerminologyReoperation ratePostoperative outcomesElixhauser Comorbidity IndexPostoperative recoveryMultivariate analysisSingle-level lumbar discectomyTestosterone replacement therapy patientsMyocardial infarctionOrthopedic surgeryKaplan-Meier survival analysisEmergency departmentLumbar spinal proceduresLog-rank testMonths of surgeryRetrospective cohort studyPostoperative adverse eventsEnhanced postoperative recoveryMinor adverse events35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients
Seddio A, McNamara K, Gouzoulis M, Jabbouri S, Ratnasamy P, Rubio D, Grauer J. 35. Comparable risk of adverse events following cervicothoracic interlaminar and transforaminal epidural injections: an analysis of 1.29 million patients. The Spine Journal 2024, 24: s19. DOI: 10.1016/j.spinee.2024.06.478.Peer-Reviewed Original ResearchAdverse eventsSpinal neurologic deficitsStatistically significant differenceCurrent Procedural TerminologyElixhauser Comorbidity IndexEpidural injectionAdult patientsNeurological deficitsAdverse outcomesMultivariate analysisED visitsIncidence of adverse eventsEpidural spinal injectionsTransforaminal epidural injectionsEmergency departmentTransforaminal (TFRisk of adverse eventsSignificant differenceRetrospective cohort studyMinor adverse eventsSampled adult patientsOutcome measures IncidencePotential adverse eventsSpinal injectionPatient age100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes
Seddio A, Gouzoulis M, Vasudevan R, Dhodapkar M, Jabbouri S, Zhu J, Rubio D, Grauer J. 100. Semaglutide associated with improved postoperative outcomes following single-level posterior lumbar fusion for patients with type II diabetes. The Spine Journal 2024, 24: s52-s53. DOI: 10.1016/j.spinee.2024.06.543.Peer-Reviewed Original ResearchSingle-level posterior lumbar fusionPosterior lumbar fusionSodium-glucose transport protein 2 inhibitorsImpact of semaglutideHospital readmissionPostoperative outcomesElixhauser Comorbidity IndexED visitsT2DM patientsCurrent Procedural TerminologyEmergency departmentLumbar fusionAdverse eventsOdds of hospital readmissionOutcome measures IncidenceRisk of type I errorInferior postoperative outcomesDiagnosis of T2DMMonths of surgeryYear of surgeryRetrospective cohort studyMinor adverse eventsType II diabetes mellitusMatched 1:4Management of diabetes
2023
The Burden of Revision Total Ankle Replacement Has Markedly Increased from 2010 to 2020
Ratnasamy P, Maloy G, Oghenesume O, Peden S, Grauer J, Oh I. The Burden of Revision Total Ankle Replacement Has Markedly Increased from 2010 to 2020. Foot & Ankle Orthopaedics 2023, 8: 2473011423s00199. PMCID: PMC10750518, DOI: 10.1177/2473011423s00199.Peer-Reviewed Original ResearchExplant surgeryRisk factorsYounger ageComorbidity burdenIndependent predictorsFemale sexRevision surgeryMultivariate logistic regression analysisHigher comorbidity burdenPatient comorbidity burdenRevision total ankle replacementTotal ankle replacement surgeryRetrospective cohort studyIndependent risk factorImplant survival rateElixhauser Comorbidity IndexRisk of revisionTiming of revisionLogistic regression analysisSite of careTotal ankle replacementLarge national databaseAnkle replacement surgeryOccurrence of revisionExplant patientsThe Burden of Revision Total Ankle Replacement Has Increased From 2010 to 2020
Ratnasamy P, Maloy G, Oghenesume O, Peden S, Grauer J, Oh I. The Burden of Revision Total Ankle Replacement Has Increased From 2010 to 2020. Foot & Ankle Orthopaedics 2023, 8: 24730114231198234. PMID: 37767009, PMCID: PMC10521287, DOI: 10.1177/24730114231198234.Peer-Reviewed Original ResearchElixhauser Comorbidity IndexHigher Elixhauser comorbidity indexRetrospective cohort studyCohort studyIndependent predictorsAnnual incidenceRevision surgeryRisk factorsYounger ageMultivariate logistic regression analysisRevision total ankle replacementTotal ankle replacement surgeryIndependent risk factorImplant survival rateTiming of revisionLogistic regression analysisSite of careTotal ankle replacementAnkle replacement surgeryExplant patientsExplant surgeryComorbidity indexPatient factorsIndex procedureFemale sexFactors Associated With Increased Opioid Prescriptions Following Anterior Cruciate Ligament Reconstruction in Opioid-Naïve Patients
Yalcin S, Joo P, McLaughlin W, Moran J, Caruana D, Flores M, Grauer J, Medvecky M. Factors Associated With Increased Opioid Prescriptions Following Anterior Cruciate Ligament Reconstruction in Opioid-Naïve Patients. Arthroscopy Sports Medicine And Rehabilitation 2023, 5: 100740. PMID: 37645399, PMCID: PMC10461142, DOI: 10.1016/j.asmr.2023.04.023.Peer-Reviewed Original ResearchAnterior cruciate ligament reconstructionOpioid-naïve patientsOpioid prescriptionsCruciate ligament reconstructionOrthopaedic surgeonsMean MMEOpioid useLigament reconstructionPreoperative diagnosisArthroscopic anterior cruciate ligament reconstructionMedical providersFollowing Anterior Cruciate Ligament ReconstructionOlder ageRetrospective cohort studyCollateral ligament repairSubstance use disordersMean morphineNaïve patientsOpioid dosesPrescriber specialtyCohort studyPatient factorsChronic painAverage MMEPhysician specialtySingle-level Anterior Cervical Discectomy and Fusion Results in Lower Five-year Revisions than Posterior Cervical Foraminotomy in a Large National Cohort
Jayaram R, Joo P, Gouzoulis M, Ratnasamy P, Caruana D, Grauer J. Single-level Anterior Cervical Discectomy and Fusion Results in Lower Five-year Revisions than Posterior Cervical Foraminotomy in a Large National Cohort. Spine 2023, 48: 1266-1271. PMID: 37339256, DOI: 10.1097/brs.0000000000004754.Peer-Reviewed Original ResearchConceptsPosterior cervical foraminotomySingle-level ACDFSingle-level anterior cervical discectomyPerioperative adverse eventsAnterior cervical discectomyAdverse eventsCervical foraminotomyCervical discectomyRevision rateOdds ratioShort-term adverse eventsSimilar short-term outcomesKaplan-Meier survival analysisRetrospective cohort studySerious adverse eventsCervical disc diseaseFive-year ratesSurgical site infectionShort-term outcomesMultivariable logistic regressionLarge national cohortCumulative revision rateCervical reoperationPCF cohortCohort studyPrevious Isolated Medial Bucket-Handle Meniscus Repair Significantly Increases Risk of Subsequent Ipsilateral Anterior Cruciate Ligament Reconstruction
McLaughlin W, Gillinov S, Joo P, Moran J, Jimenez A, Grauer J, Gardner E. Previous Isolated Medial Bucket-Handle Meniscus Repair Significantly Increases Risk of Subsequent Ipsilateral Anterior Cruciate Ligament Reconstruction. Arthroscopy Sports Medicine And Rehabilitation 2023, 5: e671-e678. PMID: 37388885, PMCID: PMC10300536, DOI: 10.1016/j.asmr.2023.03.008.Peer-Reviewed Original ResearchAnterior cruciate ligament reconstructionBucket-handle meniscus tearsSubsequent anterior cruciate ligament reconstructionCruciate ligament reconstructionBucket-handle meniscus repairControl groupLigament reconstructionMeniscal injuryMeniscus surgeryGreater oddsMeniscus repairRetrospective cohort studyAge-matched patientsKaplan-Meier analysisCohort studyPrior surgeryRetrospective reviewInclusion criteriaMeniscus tearsHigh riskGeneral populationMeniscal tearsOperative methodPatientsLevel IIIUrgent Care Versus Emergency Department Utilization for Foot and Ankle Fractures
Dhodapkar M, Gouzoulis M, Halperin S, Modrak M, Yoo B, Grauer J. Urgent Care Versus Emergency Department Utilization for Foot and Ankle Fractures. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 31: 984-989. PMID: 37253245, DOI: 10.5435/jaaos-d-22-01097.Peer-Reviewed Original ResearchConceptsUrgent care facilityAnkle fracturesEmergency departmentED utilizationCare facilitiesUrgent careOdds ratioICD-10 diagnosis codesCertain injury typesUrgent care utilizationRetrospective cohort studyUrgent care visitsYears old presentingMinority of patientsEmergency department utilizationOld presentingCare visitsAdult patientsCare algorithmCohort studyIndependent predictorsCare utilizationMultivariable analysisCommon injuriesDiagnosis codesRheumatoid arthritis patients are at increased risk for adverse events following lumbar discectomy
Ratnasamy P, Rudisill K, Gouzoulis M, Kammien A, Grauer J. Rheumatoid arthritis patients are at increased risk for adverse events following lumbar discectomy. The Spine Journal 2023, 23: 990-996. PMID: 36990283, DOI: 10.1016/j.spinee.2023.03.012.Peer-Reviewed Original ResearchConceptsLumbar discectomy patientsAdverse eventsRheumatoid arthritisLumbar discectomyPatient ageDiscectomy patientsMinor adverse eventsRetrospective cohort studyLumbar spinal surgeryPatient's medication regimenElixhauser Comorbidity IndexExclusion of patientsRA medicationsComorbidity indexCohort studyMedication regimenPrior diagnosisPredictive factorsAdverse outcomesSubgroup analysisSpinal surgeryInfection diagnosisAutoinflammatory diseasesHigher oddsDiscectomyIs There Utility to Requiring Spine MRI Pre-authorizations? Pre-authorizations
Kebaish K, Galivanche A, Mercier M, Varthi A, Rubin L, Grauer J. Is There Utility to Requiring Spine MRI Pre-authorizations? Pre-authorizations. Clinical Spine Surgery A Spine Publication 2023, 36: 186-189. PMID: 36728293, DOI: 10.1097/bsd.0000000000001422.Peer-Reviewed Original ResearchConceptsSpine magnetic resonance imagingMagnetic resonance imagingSpine centerAcademic spine centerRetrospective cohort studySignificant increased oddsMultivariate logistic regressionPatient undergoing treatmentEventual dispositionInsurance carriersCohort studyIncreased oddsCommercial insurance carriersMRI requestsMRI ordersUndergoing treatmentBACKGROUND DATAGreater oddsPreauthorization processCommercial insuranceResonance imagingSpine scansLogistic regressionPreauthorizationScans
2022
Emergency Department Visits Within 90 Days of Total Ankle Replacement
Ratnasamy PP, Kammien AJ, Gouzoulis MJ, Oh I, Grauer JN. Emergency Department Visits Within 90 Days of Total Ankle Replacement. Foot & Ankle Orthopaedics 2022, 7: 24730114221134255. PMID: 36324696, PMCID: PMC9619275, DOI: 10.1177/24730114221134255.Peer-Reviewed Original ResearchElixhauser Comorbidity IndexSurgical site painRetrospective cohort studyED visitsSite painCohort studyHealth care utilization/costsHigher Elixhauser comorbidity indexPain management pathwayPostoperative ED visitsPostoperative hospital lengthEmergency department visitsDay of surgeryLogistic regression analysisSite of careTotal ankle replacementHealth care costsComorbidity indexHospital lengthED utilizationDepartment visitsPatient factorsPostoperative weekEmergency departmentFemale sexEmergency Department Visits Within 90 Days of Total Ankle Arthroplasty
Ratnasamy P, Kammien A, Gouzoulis M, Grauer J. Emergency Department Visits Within 90 Days of Total Ankle Arthroplasty. Foot & Ankle Orthopaedics 2022, 7: 2473011421s00895. PMCID: PMC9679845, DOI: 10.1177/2473011421s00895.Peer-Reviewed Original ResearchTotal ankle arthroplastyElixhauser Comorbidity IndexSurgical site painED visitsSite painTAA patientsAnkle arthroplastyRisk factorsCommon reasonHealth care utilization/costsHigher Elixhauser comorbidity indexPostoperative ED visitsRetrospective cohort studyEmergency department visitsDay of surgeryLogistic regression analysisComorbidity indexCohort studyED utilizationDepartment visitsPatient factorsPostoperative weekEmergency departmentPatient populationFemale sexPhysical Therapy Utilization Within 90 Days of Total Ankle Arthroplasty
Ratnasamy P, Gouzoulis M, Kammien A, Grauer J. Physical Therapy Utilization Within 90 Days of Total Ankle Arthroplasty. Foot & Ankle Orthopaedics 2022, 7: 2473011421s00896. PMCID: PMC9679831, DOI: 10.1177/2473011421s00896.Peer-Reviewed Original ResearchTotal ankle arthroplastyElixhauser Comorbidity IndexPhysical therapyPatient factorsTAA patientsAnkle arthroplastyHigher Elixhauser comorbidity indexPhysical therapy utilizationRetrospective cohort studyDay of surgeryMedicaid insurance coverageLogistic regression analysisComorbidity indexCohort studyPatients surgeryPredictive factorsTherapy utilizationOutpatient settingSurgeryGreater incidenceMultivariate analysisOlder ageFirst weekSeventh weekInsurance coverageHome and Outpatient Physical Therapy Utilization Following Total Ankle Replacement
Ratnasamy P, Gouzoulis M, Kammien A, Oh I, Grauer J. Home and Outpatient Physical Therapy Utilization Following Total Ankle Replacement. Foot & Ankle Orthopaedics 2022, 7: 24730114221146175. PMID: 36582653, PMCID: PMC9793015, DOI: 10.1177/24730114221146175.Peer-Reviewed Original ResearchTotal ankle replacementRetrospective cohort studyElixhauser Comorbidity IndexPhysical therapyCohort studyPatient factorsTAR patientsAnkle replacementPhysical therapy utilizationDay of surgeryInpatient physical therapyLogistic regression analysisFrequency of homeComorbidity indexIndependent predictorsMedicaid insurancePatients surgeryPredictive factorsTherapy utilizationCare pathwayAdministrative codingSurgeryLevel IIIPatientsFirst weekUnderweight patients are the highest risk body mass index group for perioperative adverse events following stand-alone anterior lumbar interbody fusion
Ottesen TD, Galivanche AR, Greene JD, Malpani R, Varthi AG, Grauer JN. Underweight patients are the highest risk body mass index group for perioperative adverse events following stand-alone anterior lumbar interbody fusion. The Spine Journal 2022, 22: 1139-1148. PMID: 35231643, DOI: 10.1016/j.spinee.2022.02.012.Peer-Reviewed Original ResearchConceptsBody mass indexNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseAnterior lumbar interbody fusionObese class 1Improvement Program databaseClass 2 patientsAdverse eventsUnderweight patientsBMI categoriesAdverse outcomesBMI spectrumInterbody fusionProgram databaseTwo-level anterior lumbar interbody fusionSurgeons National Surgical Quality Improvement Program databaseMultivariate analysisThirty-day adverse eventsWorld Health Organization categoriesBody mass index groupsPostoperative adverse eventsRetrospective cohort studyPerioperative adverse eventsNormal-weight subjectsPost-operative infection
2021
Centers for Medicare & Medicaid Services' 2018 Removal of Total Knee Arthroplasty From the Inpatient-only List Led to Broad Changes in Hospital Length of Stays
Rankin KA, Freedman IG, Rubin LE, Grauer JN. Centers for Medicare & Medicaid Services' 2018 Removal of Total Knee Arthroplasty From the Inpatient-only List Led to Broad Changes in Hospital Length of Stays. Journal Of The American Academy Of Orthopaedic Surgeons 2021, 29: 1061-1067. PMID: 33960970, DOI: 10.5435/jaaos-d-20-01228.Peer-Reviewed Original ResearchConceptsTotal knee arthroplastyHospital lengthKnee arthroplastyNational Surgical Quality Improvement Program databaseQuality Improvement Program databaseMedicare eligibilityCategorical data comparisonsOverall practice patternsRetrospective cohort studyImprovement Program databaseSame dayRemoval of TKAPearson's chi-squared testChi-squared testMann-Whitney testLOS daysProlonged LOSMost patientsTKA patientsCohort studyMore patientsPractice patternsPatient characterizationProgram databaseActual LOS
2020
Characteristics and Predictors of HCAHPS Nonresponse After Spine Surgery.
Malpani R, Adrados M, Mercier MR, McLynn RP, Galivanche AR, Pathak N, Grauer JN. Characteristics and Predictors of HCAHPS Nonresponse After Spine Surgery. Spine 2020, 45: e448-e456. PMID: 31609883, PMCID: PMC7113123, DOI: 10.1097/brs.0000000000003287.Peer-Reviewed Original ResearchConceptsSpine surgery patientsSpine surgeryHCAHPS surveyPerioperative outcomesAdverse eventsPatient characteristicsSurgery patientsSingle institutionMultivariate analysisLonger hospital lengthHigher American SocietyMajor adverse eventsMinor adverse eventsRetrospective cohort studyMinority of patientsPatient satisfaction surveyHospital Consumer AssessmentSatisfaction surveyNonresponder biasHospital lengthPatient demographicsCohort studyHospital readmissionRetrospective analysisBACKGROUND DATA