2024
Total Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival.
Gillinov S, Modrak M, Park N, Monahan P, Wilhelm C, Lee M, Mahatme R, Fong S, Moran J, Grauer J, Jimenez A. Total Shoulder Arthroplasty in Patients With Hemophilia A: Greater Odds of Postoperative Bleeding and Thromboembolic Events but No Difference in 5-year Implant Survival. Clinical Orthopaedics And Related Research® 2024 PMID: 39246053, DOI: 10.1097/corr.0000000000003209.Peer-Reviewed Original ResearchVenous thromboembolic eventsTotal shoulder arthroplastyHemophilia AImplant survivalMatched controlsThromboembolic eventsElixhauser Comorbidity IndexMale patientsAdverse eventsShoulder arthroplastyProsthesis survivalThromboembolic adverse eventsVenous thromboembolic event prophylaxisKaplan-Meier analysisFactor VIII levelsRevers total shoulder arthroplastyIndividual patient basisOdds of postoperative bleedingPostoperative bleedingBleeding complicationsTranexamic acidNinety-dayPatient basisControl cohortComorbidity indexOutcomes following total shoulder arthroplasty in patients with systemic lupus erythematosus
Salib A, Sanchez J, Huggins L, Seddio A, Dhodapkar M, Smith-Voudouris J, Norman M, Koumpouras F, Grauer J. Outcomes following total shoulder arthroplasty in patients with systemic lupus erythematosus. Journal Of Shoulder And Elbow Surgery 2024 PMID: 39154846, DOI: 10.1016/j.jse.2024.07.008.Peer-Reviewed Original ResearchSystemic lupus erythematosus patientsSystemic lupus erythematosusTotal shoulder arthroplastyAdverse eventsImplant survivalLupus erythematosusMultivariate analysisShoulder arthroplastyIncreased oddsTotal shoulder arthroplasty patientsNon-SLE patientsMultivariate logistic regressionImmunomodulatory therapyPostoperative complicationsElixhauser Comorbidity IndexAdult patientsNinety-dayUnivariate analysisSurgical planningComorbidity indexPatient counselingGlenohumeral osteoarthritisPatientsComorbid conditionsOrthopedic-relatedTotal Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events
Sanchez J, Jiang W, Dhodapkar M, Radford Z, Rubin L, Grauer J. Total Hip Arthroplasty in Patients Who Have Factor V Leiden: Elevated Risks Isolated to Venous Thromboembolism Events. The Journal Of Arthroplasty 2024, 39: 2421-2426. PMID: 38838962, DOI: 10.1016/j.arth.2024.05.083.Peer-Reviewed Original ResearchFactor V LeidenAdverse eventsChemoprophylactic agentV LeidenMultivariate analysisFactor V Leiden patientsTotal hip arthroplastyPatients to venous thromboembolismLog-rank testIncreased VTE riskVenous thromboembolic eventsElevated riskPerioperative adverse eventsPre-existing comorbiditiesAdministrative claims databaseInherited thrombophiliaThromboembolic eventsElixhauser Comorbidity IndexAdult patientsVenous thromboembolismImplant survivalVTE riskComorbidity indexClaims databaseHip arthroplasty
2023
Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications
Halperin S, Dhodapkar M, Radford Z, Kaszuba S, Rubin L, Grauer J. Patients With Cystic Fibrosis Undergoing Total Hip and Total Knee Arthroplasty Are at Increased Risk for Perioperative Complications. Journal Of The American Academy Of Orthopaedic Surgeons 2023, 32: 309-315. PMID: 38165956, DOI: 10.5435/jaaos-d-23-00783.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyUrinary tract infectionPostoperative eventsCystic fibrosisPerioperative outcomesAdverse eventsTract infectionsPleural effusionKnee arthroplastyControl subjectsRevision rateAcute kidney injuryElixhauser Comorbidity IndexRisk of surgeryMultivariable logistic regressionComorbidity indexKidney injuryPerioperative complicationsRespiratory failureTKA patientsCardiac eventsPearlDiver databaseImplant survivalTotal hip
2022
Total shoulder arthroplasty: ninety-day adverse events and 5-year implant survival in patients with hidradenitis suppurativa
Gouzoulis M, Ratnasamy P, Caruana D, Wiznia D, Medvecky M, Grauer J. Total shoulder arthroplasty: ninety-day adverse events and 5-year implant survival in patients with hidradenitis suppurativa. Seminars In Arthroplasty JSES 2022, 32: 676-680. DOI: 10.1053/j.sart.2022.07.012.Peer-Reviewed Original ResearchTotal shoulder arthroplastySurgical site infectionMinor adverse eventsAdverse eventsSite infectionTSA patientsImplant survivalHS patientsSkin lesionsLog-rank Mantel-Cox testFive-year implant survivalKaplan-Meier survival curvesHigher comorbidity burdenMethods Adult patientsNon-HS groupsSevere adverse eventsElixhauser Comorbidity IndexChronic skin disorderPotential risk factorsMantel-Cox testRisk of infectionComorbidity burdenComorbidity indexPostoperative complicationsReoperation rateHidradenitis Suppurativa Leads to Increased Risk of Wound-Related Complications following Total Joint Arthroplasty
Gouzoulis MJ, Kammien AJ, Caruana DL, Wiznia DH, Grauer JN. Hidradenitis Suppurativa Leads to Increased Risk of Wound-Related Complications following Total Joint Arthroplasty. Arthroplasty Today 2022, 16: 169-174. PMID: 35789782, PMCID: PMC9249970, DOI: 10.1016/j.artd.2022.05.013.Peer-Reviewed Original ResearchTotal knee arthroplastyTotal hip arthroplastyAdverse eventsHS patientsImplant survivalSkin lesionsKaplan-Meier survival curvesNon-HS patientsSurgical site infectionElixhauser Comorbidity IndexInflammatory skin lesionsSpecific adverse eventsLog-rank testPotential risk factorsTotal joint arthroplastyWound-related issuesRisk of woundComorbidity indexAdult patientsSite infectionDegenerative etiologyWound dehiscenceKnee arthroplastyRevision rateRisk factorsTotal Hip Arthroplasty in Patients With Classic Hemophilia: A Matched Comparison of 90-Day Outcomes and 5-Year Implant Survival
Gillinov SM, Burroughs PJ, Moore HG, Rubin LE, Frumberg DB, Grauer JN. Total Hip Arthroplasty in Patients With Classic Hemophilia: A Matched Comparison of 90-Day Outcomes and 5-Year Implant Survival. The Journal Of Arthroplasty 2022, 37: 1333-1337. PMID: 35257821, PMCID: PMC9177736, DOI: 10.1016/j.arth.2022.02.107.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyNon-hemophilia patientsMinor adverse eventsSerious adverse eventsAdverse eventsClassic hemophiliaHaemophilia patientsImplant survivalHip arthroplastyGreater oddsMultivariate analysisFive-year implant survivalPrimary total hip arthroplastyAcute kidney injuryVenous thromboembolism prophylaxisElixhauser Comorbidity IndexKaplan-Meier analysisEvidence-based guidelinesThromboembolism prophylaxisVTE prophylaxisComorbidity indexKidney injuryTHA patientsFactor replacementRetrospective studyTotal shoulder arthroplasty for osteoarthritis in patients with Parkinson's disease: a matched comparison of 90-day adverse events and 5-year implant survival
Moore HG, Kahan JB, Sherman JJZ, Burroughs PJ, Donohue KW, Grauer JN. Total shoulder arthroplasty for osteoarthritis in patients with Parkinson's disease: a matched comparison of 90-day adverse events and 5-year implant survival. Journal Of Shoulder And Elbow Surgery 2022, 31: 1436-1441. PMID: 35176495, DOI: 10.1016/j.jse.2022.01.113.Peer-Reviewed Original ResearchConceptsTotal shoulder arthroplastyImplant survivalAdverse eventsParkinson's diseaseShoulder arthroplastyDisease cohortDisease populationHigher oddsShort-term adverse eventsNinety-day incidenceChronic kidney diseaseCongestive heart failureCoronary artery diseaseElixhauser Comorbidity IndexLong-term outcomesLog-rank testCase-control studyParkinson's disease cohortParkinson's disease populationShort-term riskPeriprosthetic dislocationComorbidity indexPostoperative periodProsthetic dislocationArtery disease
2021
Patients With Ehlers-Danlos Syndromes Experience Higher Rates of Prosthetic Dislocation After Total Hip Arthroplasty and Worse Implant Survival at 5 Years
Moore HG, Burroughs PJ, Rubin LE, Frumberg DB, Sculco PK, Grauer JN. Patients With Ehlers-Danlos Syndromes Experience Higher Rates of Prosthetic Dislocation After Total Hip Arthroplasty and Worse Implant Survival at 5 Years. Journal Of The American Academy Of Orthopaedic Surgeons 2021, 30: 177-183. PMID: 34967762, DOI: 10.5435/jaaos-d-21-00347.Peer-Reviewed Original ResearchConceptsEhlers-Danlos syndromeTotal hip arthroplastyImplant survivalHip arthroplastyAdverse eventsDiagnosis of EDSGenetic connective tissue disorderNinety-day incidenceWorse implant survivalHigh rateDay of surgeryLong-term outcomesLog-rank testMultivariate logistic regressionConnective tissue disordersMultiple organ systemsConnective tissue laxityPerioperative dislocationPeriprosthetic dislocationPostoperative complicationsPostoperative periodProsthetic dislocationHospital readmissionControl subjectsAdministrative databasesTotal Joint Arthroplasty in Patients With Achondroplasia: Comparison of 90-Day Adverse Events and 5-Year Implant Survival
Moore HG, Schneble CA, Kahan JB, Polkowski GG, Rubin LE, Grauer JN. Total Joint Arthroplasty in Patients With Achondroplasia: Comparison of 90-Day Adverse Events and 5-Year Implant Survival. Arthroplasty Today 2021, 11: 151-156. PMID: 34584919, PMCID: PMC8452593, DOI: 10.1016/j.artd.2021.08.011.Peer-Reviewed Original ResearchTotal joint arthroplastyAdverse eventsImplant survivalJoint arthroplastyFive-year implant survivalShort-term adverse eventsPrimary total hipSurgical site infectionLong-term implant successMultivariate logistic regressionTotal knee arthroplastyCommon skeletal dysplasiaMedical comorbiditiesSite infectionTotal hipPatient populationKnee arthroplastyAdministrative databasesHigher oddsLarge cohortGreater oddsPatientsImplant successSurvival curvesArthroplastyTotal Hip Arthroplasty in Patients With Cerebral Palsy: A Matched Comparison of 90-Day Adverse Events and 5-Year Implant Survival
Moore HG, Gardezi M, Burroughs PJ, Rubin LE, Frumberg DB, Grauer JN. Total Hip Arthroplasty in Patients With Cerebral Palsy: A Matched Comparison of 90-Day Adverse Events and 5-Year Implant Survival. The Journal Of Arthroplasty 2021, 36: 3534-3537. PMID: 34176692, DOI: 10.1016/j.arth.2021.05.039.Peer-Reviewed Original ResearchConceptsTotal hip arthroplastyFive-year implant survivalUrinary tract infectionCerebral palsyImplant survivalAdverse eventsTract infectionsComorbid factorsPeriprosthetic fracturesHigher oddsHip arthroplastyPerioperative urinary tract infectionNinety-day incidencePerioperative adverse eventsLong-term outcomesLog-rank testKaplan-Meier plotsMultivariate logistic regressionPerioperative complicationsPostoperative complicationsCP cohortHospital readmissionMatched ComparisonAdministrative databasesPatients