2021
An independent assessment of an artificial intelligence system for prostate cancer detection shows strong diagnostic accuracy
Perincheri S, Levi AW, Celli R, Gershkovich P, Rimm D, Morrow JS, Rothrock B, Raciti P, Klimstra D, Sinard J. An independent assessment of an artificial intelligence system for prostate cancer detection shows strong diagnostic accuracy. Modern Pathology 2021, 34: 1588-1595. PMID: 33782551, PMCID: PMC8295034, DOI: 10.1038/s41379-021-00794-x.Peer-Reviewed Original ResearchConceptsMemorial Sloan-Kettering Cancer CenterCore biopsyPredictive valueDiagnostic accuracyProstate core needle biopsiesCore needle biopsySurgical pathology practiceNegative predictive valueProstate core biopsiesPositive predictive valueProstate cancer detectionStrong diagnostic accuracyPoor quality scansCancer detectionCancer CenterProstate biopsyLeading causeNeedle biopsyTransrectal approachProstate cancerProstatic adenocarcinomaProstate carcinomaBiopsyPathology practiceProstate
2020
Pulmonary Adenocarcinoma Metastatic to Periocular Skin and Orbital Tissue Presenting as Orbital Cellulitis.
Li E, Sinard J, Sohrab M. Pulmonary Adenocarcinoma Metastatic to Periocular Skin and Orbital Tissue Presenting as Orbital Cellulitis. Ophthalmic Plastic And Reconstructive Surgery 2020, 36: e28-e30. PMID: 31789787, DOI: 10.1097/iop.0000000000001534.Peer-Reviewed Original ResearchConceptsOrbital inflammationAdenocarcinoma metastaticMetastatic lung cancerLife-saving managementIntraorbital soft tissuesBroad-spectrum antibioticsOccult malignancyAdjuvant radiationSystemic chemotherapyInitial presentationOrbital cellulitisLung cancerPeriocular skinSubcutaneous massHigh indexTissue biopsiesSoft tissueMetastaticBiopsyInflammationDiagnosisFirst reportCellulitisChemotherapyPatients
2018
Optimal Intraoperative Assessment of Gastric Margins
Celli R, Barbieri AL, Colunga M, Sinard J, Gibson JA. Optimal Intraoperative Assessment of Gastric Margins. American Journal Of Clinical Pathology 2018, 150: 353-363. PMID: 30020407, DOI: 10.1093/ajcp/aqy062.Peer-Reviewed Original ResearchConceptsIntraoperative pathology consultationGastric marginPositive marginsTumor distanceMajority of casesRepresentative sectionsR0 resectionConsecutive patientsGastroesophageal junctionTumor sizeNegative marginsPatient outcomesIntraoperative assessmentPathology consultationPatientsStrong associationMargin assessment
1998
Albumin gene expression in adenocarcinomas with hepatoid differentiation
Foschini MP, Baccarini P, Dal Monte P, Sinard J, Eusebi V, Rosai J. Albumin gene expression in adenocarcinomas with hepatoid differentiation. Virchows Archiv 1998, 433: 537-541. PMID: 9870687, DOI: 10.1007/s004280050286.Peer-Reviewed Original ResearchConceptsAlpha-fetoproteinHepatoid areasHepatocellular differentiationCase 2Case 1Hepatoid adenocarcinomaHuman albumin mRNAHepatoid differentiationGastric antrumAlbumin mRNAHepatoid cellsImmunohistochemical profileUrinary bladderHepatocellular carcinomaAdenocarcinomatous areasAlbumin gene expressionProminent nucleoliOccasional cellsOval nucleiAdenocarcinomaTumor cellsPolygonal cellsSitu hybridization techniqueCEA antibodyTumors
1994
Hepatoid adenocarcinoma in the urinary bladder. Unusual localization of a newly recognized tumor type
Sinard J, Macleay L, Melamed J. Hepatoid adenocarcinoma in the urinary bladder. Unusual localization of a newly recognized tumor type. Cancer 1994, 73: 1919-1925. PMID: 7511041, DOI: 10.1002/1097-0142(19940401)73:7<1919::aid-cncr2820730724>3.0.co;2-l.Peer-Reviewed Original ResearchConceptsHepatoid adenocarcinomaHepatocellular differentiationAlpha-fetoproteinHepatoid tumorsUrinary bladderGerm cell tumorsAnterior bladder wallUnusual histologic featuresIntracytoplasmic hyaline globulesHepatoid areasClinicopathologic featuresHistologic featuresBladder tumorsBile productionCell tumorsHepatoid cellsImmunohistochemical criteriaBladder wallGlandular patternTumor massUnusual neoplasmCarcinoembryonic antigenHyaline globulesTumor typesAdenocarcinoma