2009
Factor VII–Verteporfin for Targeted Photodynamic Therapy in a Rat Model of Choroidal Neovascularization
Lu F, Hu Z, Sinard J, Garen A, Adelman RA. Factor VII–Verteporfin for Targeted Photodynamic Therapy in a Rat Model of Choroidal Neovascularization. Investigative Ophthalmology & Visual Science 2009, 50: 3890-3896. PMID: 19357351, DOI: 10.1167/iovs.08-2833.Peer-Reviewed Original ResearchConceptsVisudyne photodynamic therapyChoroidal neovascularizationCNV lesionsTargeted photodynamic therapyDay 7Rat modelSafety of PDTPhotodynamic therapyOcular side effectsBrown Norway ratsFrequency of leakageFluorescein angiographyEfficacious doseHistopathologic evaluationLaser photocoagulationSide effectsFactor VIIDay 14LesionsNormal vasculatureRatsEndothelial cellsTherapyDoseNeovascularization
1998
Orbital Melanoma Presenting as Orbital Cellulitis
Fezza J, Chaudhry I, Kwon Y, Grannum E, Sinard J, Wolfley D. Orbital Melanoma Presenting as Orbital Cellulitis. Ophthalmic Plastic And Reconstructive Surgery 1998, 14: 286-289. PMID: 9700739, DOI: 10.1097/00002341-199807000-00012.Peer-Reviewed Original ResearchConceptsOrbital cellulitisChoroidal melanomaMost choroidal melanomasNecrotic choroidal melanomaSpindle B melanomaIntraocular involvementMelanoma presentingOrbital inflammationPostoperative radiationAcute infectionEpithelioid areasEarly suspicionHistopathologic analysisMelanomaTumorsCellulitisLesionsBest chanceInflammationPatientsPresentingMalignancyEnucleationInfectionSuspicion