2016
Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks
Sherva R, Wang Q, Kranzler H, Zhao H, Koesterer R, Herman A, Farrer LA, Gelernter J. Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks. JAMA Psychiatry 2016, 73: 472. PMID: 27028160, PMCID: PMC4974817, DOI: 10.1001/jamapsychiatry.2016.0036.Peer-Reviewed Original ResearchConceptsCannabis dependenceNeuronal calcium homeostasisGenetic factorsMajor depressive disorderSushi multiple domains-1 (CSMD1) geneSubstance abuse treatment centersSpecific genetic risk factorsGenetic risk factorsShared genetic riskPotential genetic factorsCentral nervous system developmentCriterion countsCannabis dependence severityDomain 1 geneCAD riskMean ageRisk factorsDepressive disorderNervous system developmentMajor depressionLarge cohortMAIN OUTCOMEGenome-wide association studiesTreatment centersCalcium homeostasis
2013
Child Abuse and Epigenetic Mechanisms of Disease Risk
Yang BZ, Zhang H, Ge W, Weder N, Douglas-Palumberi H, Perepletchikova F, Gelernter J, Kaufman J. Child Abuse and Epigenetic Mechanisms of Disease Risk. American Journal Of Preventive Medicine 2013, 44: 101-107. PMID: 23332324, PMCID: PMC3758252, DOI: 10.1016/j.amepre.2012.10.012.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentCase-Control StudiesChildChild AbuseChild, PreschoolDNADNA MethylationEpigenesis, GeneticFemaleGenome-Wide Association StudyHumansMaleOligonucleotide Array Sequence AnalysisRisk FactorsSalivaConceptsEpigenetic mechanisms
2012
Array‐Based Profiling of DNA Methylation Changes Associated with Alcohol Dependence
Zhang H, Herman AI, Kranzler HR, Anton RF, Zhao H, Zheng W, Gelernter J. Array‐Based Profiling of DNA Methylation Changes Associated with Alcohol Dependence. Alcohol Clinical And Experimental Research 2012, 37: e108-e115. PMID: 22924764, PMCID: PMC3511647, DOI: 10.1111/j.1530-0277.2012.01928.x.Peer-Reviewed Original ResearchAlcoholismBlack or African AmericanDNA MethylationFemaleGenetic Association StudiesHumansMaleOligonucleotide Array Sequence AnalysisWhite People
2011
M3: an improved SNP calling algorithm for Illumina BeadArray data
Li G, Gelernter J, Kranzler HR, Zhao H. M3: an improved SNP calling algorithm for Illumina BeadArray data. Bioinformatics 2011, 28: 358-365. PMID: 22155947, PMCID: PMC3268244, DOI: 10.1093/bioinformatics/btr673.Peer-Reviewed Original ResearchAlgorithmsCase-Control StudiesCluster AnalysisComputational BiologyGenotypeHapMap ProjectHumansModels, GeneticOligonucleotide Array Sequence AnalysisPolymorphism, Single NucleotideVariation in NGFB is associated with primary affective disorders in women
Cui D, Zhang H, Yang B, Listman JB, Li D, Price LH, Carpenter LL, Tyrka AR, Anton RF, Kranzler HR, Gelernter J. Variation in NGFB is associated with primary affective disorders in women. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2011, 156: 401-412. PMID: 21294249, PMCID: PMC3108453, DOI: 10.1002/ajmg.b.31175.Peer-Reviewed Original Research