2023
International Perspectives on GFR Estimation and Race-Based Adjustments
El-Khoury J, Karger A, Cavalier E, Kalyesubula R, Teo B, Costa e Silva V, Inker L. International Perspectives on GFR Estimation and Race-Based Adjustments. Clinical Chemistry 2023, 69: 796-802. PMID: 37453046, DOI: 10.1093/clinchem/hvad095.Peer-Reviewed Original Research
2022
Resolving icteric interference by a novel photoisomerization device: Bilibox
Vera MA, Koch CD, El-Khoury JM. Resolving icteric interference by a novel photoisomerization device: Bilibox. Clinical Biochemistry 2022, 115: 112-115. PMID: 35882276, DOI: 10.1016/j.clinbiochem.2022.07.004.Peer-Reviewed Original ResearchConceptsDirect bilirubinIcteric interferenceAforementioned analytesChemical reactivityPhotoisomerizationRoutine laboratory testingEndogenous interferencesBilirubin elevationBaseline creatinineAssay reagentsLaboratory testingDilutional methodMin of treatmentCreatinineEnzymatic creatinine assayIcterusBilirubinChemistry testingClinical samplesCreatinine assaysHeparin vacutainersTreatmentAnalytesIctericRepeat measurements
2021
AACC Guidance Document on Laboratory Investigation of Acute Kidney Injury
El-Khoury JM, Hoenig MP, Jones GRD, Lamb EJ, Parikh CR, Tolan NV, Wilson FP. AACC Guidance Document on Laboratory Investigation of Acute Kidney Injury. The Journal Of Applied Laboratory Medicine 2021, 6: 1316-1337. PMID: 33973621, DOI: 10.1093/jalm/jfab020.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsAcute kidney injuryKidney injuryNew biomarkersPotential acute kidney injuryInsulin-like growth factor binding protein 7Growth factor binding protein 7Early detectionLong-term complicationsLaboratory investigationsEmergence of biomarkersHealth care costsBinding protein 7AKI alertsKidney damageClinical indicationsCystatin CSudden episodeCare costsTissue inhibitorDiagnostic thresholdMetalloproteinases 2Test utilizationPreponderance of evidenceTraditional markersExpert recommendationsIs It Time to Move On? Reexamining Race in Glomerular Filtration Rate Equations
Moderators:, El-Khoury JM, Ovalle AA, Cervinski MA, Experts:, Levey AS, Jones G, Eneanya ND, Lieske JC, Jha V. Is It Time to Move On? Reexamining Race in Glomerular Filtration Rate Equations. Clinical Chemistry 2021, 67: 585-591. PMID: 33686430, DOI: 10.1093/clinchem/hvaa333.Peer-Reviewed Original Research
2019
Practical Approach to Eliminate Bilirubin Interference in Icteric Samples for Creatinine Measurement
Charifa A, Bunch DR, El-Khoury JM. Practical Approach to Eliminate Bilirubin Interference in Icteric Samples for Creatinine Measurement. The Journal Of Applied Laboratory Medicine 2019, 4: 477-479. PMID: 31659092, DOI: 10.1373/jalm.2019.030247.Peer-Reviewed Original Research
2018
Erratic Serum Creatinine Concentrations in a Cardiac Patient
Charifa A, Bunch DR, El-Khoury JM. Erratic Serum Creatinine Concentrations in a Cardiac Patient. Clinical Chemistry 2018, 64: 1543-1544. PMID: 30266720, DOI: 10.1373/clinchem.2017.285858.Peer-Reviewed Original Research
2016
Comparison of symmetric dimethylarginine with creatinine, cystatin C and their eGFR equations as markers of kidney function
El-Khoury JM, Bunch DR, Hu B, Payto D, Reineks EZ, Wang S. Comparison of symmetric dimethylarginine with creatinine, cystatin C and their eGFR equations as markers of kidney function. Clinical Biochemistry 2016, 49: 1140-1143. PMID: 27452178, DOI: 10.1016/j.clinbiochem.2016.07.009.Peer-Reviewed Original ResearchConceptsGlomerular filtration rateKidney functionCystatin CEGFR equationsWidespread clinical useIothalamate clearanceEGFR formulasFiltration rateSymmetric dimethylargininePlasma specimensAdult populationStrong markerAbstractTextClinical useEndogenous markerCreatinineLiquid chromatography-tandem mass spectrometry methodChromatography-tandem mass spectrometry methodFurther studiesDimethylarginineRoche Cobas 8000MarkersCatabolic productsCobas 8000