2022
Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty
Del Toro-Pagán NM, Dai F, Banack T, Berlin J, Makadia SA, Rubin LE, Zhou B, Huynh P, Li J. Perineural Methylprednisolone Depot Formulation Decreases Opioid Consumption After Total Knee Arthroplasty. Journal Of Pain Research 2022, 15: 2537-2546. PMID: 36061486, PMCID: PMC9432382, DOI: 10.2147/jpr.s378243.Peer-Reviewed Original ResearchWhite blood cell countTotal knee arthroplastyActive pain scoresCumulative opioid consumptionOpioid consumptionPostoperative opioid consumptionMethylprednisolone acetateMPA groupPain scoresPostoperative dayNerve blockDEX groupKnee arthroplastySingle-injection nerve blocksConsecutive TKA patientsDaily opioid consumptionPosterior knee (IPACK) blockLocal anesthetic adjuvantBlood cell countLength of stayHigher restKnee blockHospital stayTKA patientsSecondary outcomesGlucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty
Baldev K, Dai F, Barrett C, Zhou B, Shah M, Howie B, Boominathan P, Zhao X, Li J. Glucocorticoid minimizes local anesthetic infusion requirement through adductor canal block and improves perioperative prosthetic joint range of motion in total knee arthroplasty. PLOS ONE 2022, 17: e0261949. PMID: 35081134, PMCID: PMC8791457, DOI: 10.1371/journal.pone.0261949.Peer-Reviewed Original ResearchConceptsAdductor canal blockTotal knee arthroplastyContinuous adductor canal blockPain scoresCanal blockTreatment groupsKnee arthroplastyOpioid consumptionOpioid usageGlucocorticoid injectionSingle-injection adductor canal blockControl groupSingle-center retrospective studyUnilateral total knee arthroplastyNumeric pain scoresPerioperative opioid usageCenter retrospective studyPostoperative day 1Use of glucocorticoidsLocal anesthetic adjuvantLength of stayAmount of ropivacaineRopivacaine infusionDischarge dispositionInfusion requirements
2021
Erector Spinae Plane Block for Perioperative Pain Control and Short-term Outcomes in Lumbar Laminoplasty: A Randomized Clinical Trial
Jin Y, Zhao S, Cai J, Blessing M, Zhao X, Tan H, Li J. Erector Spinae Plane Block for Perioperative Pain Control and Short-term Outcomes in Lumbar Laminoplasty: A Randomized Clinical Trial. Journal Of Pain Research 2021, 14: 2717-2727. PMID: 34512011, PMCID: PMC8423490, DOI: 10.2147/jpr.s321514.Peer-Reviewed Original ResearchErector spinae plane blockPostoperative pain scoresPain scoresGroup E patientsLumbar laminoplastyESP blockPain managementGroup EOpioid utilizationBowel functionPlane blockGeneral anesthesiaE patientsOpioid-sparing analgesic techniquesBilateral ESP blockPerioperative analgesic consumptionPerioperative pain controlAcute pain managementLower pain scoresSingle-center trialShort-term outcomesGroup G patientsAnalgesia scoresAnalgesic consumptionLaminoplasty patients
2019
Paravertebral Block with Compound Betamethasone in Laparoscopic Cholecystectomy: A Double-blind Randomized Controlled Trial
Li J, Li L, Zhang X, Li C, He D, Zhang J, Duan C, Perese F, Burzynski A, Wu CL, Dai F, Xue Y. Paravertebral Block with Compound Betamethasone in Laparoscopic Cholecystectomy: A Double-blind Randomized Controlled Trial. Cureus 2019, 11: e6023. PMID: 31824791, PMCID: PMC6886661, DOI: 10.7759/cureus.6023.Peer-Reviewed Original ResearchSingle-injection thoracic paravertebral blockThoracic paravertebral blockAddition of betamethasoneUndergoing laparoscopic cholecystectomyLaparoscopic cholecystectomyGeneral anesthesiaPain scoresParavertebral blockDouble-Blind Randomized Controlled TrialPatient undergoing laparoscopic cholecystectomyGood perioperative analgesiaMethods Eligible patientsAcute pain managementLower pain scoresLocal anesthetic infiltrationRandomized Controlled TrialsNumber of dermatomesT7-8 levelAnalgesic consumptionCompound betamethasoneEligible patientsTPVB groupAnalgesic administrationAnesthetic infiltrationPerioperative analgesiaA Practical Analgesia Approach to Fragility Hip Fracture
Li J, Dai F, Chang D, Harmon E, Ibe I, Sukumar N, Halaszynski TM, Rubin LE, OʼConnor M. A Practical Analgesia Approach to Fragility Hip Fracture. Journal Of Orthopaedic Trauma 2019, Publish Ahead of Print: &na;. PMID: 30570615, DOI: 10.1097/bot.0000000000001391.Peer-Reviewed Original ResearchConceptsFemoral nerve blockFragility hip fractureSubcapital femoral neck fracturesPain score reductionFemoral neck fracturesFemoral neck factureHip fracturePain scoresNeck fracturesIntertrochanteric fracturesScore reductionSingle-injection femoral nerve blockVisual analog scale pain scoreAcademic medical center patientsSignificant pain score reductionPain control modalitiesTherapeutic Level IVScale pain scoresHip fracture patientsObservational study SETTINGMedical Center patientsAnalgesic modalitiesFragility hipOpioid consumptionFracture patients
2018
The role of sciatic nerve block to complement femoral nerve block in total knee arthroplasty: a meta-analysis of randomized controlled trials
Zorrilla-Vaca A, Li J. The role of sciatic nerve block to complement femoral nerve block in total knee arthroplasty: a meta-analysis of randomized controlled trials. Journal Of Anesthesia 2018, 32: 341-350. PMID: 29520522, DOI: 10.1007/s00540-018-2480-1.Peer-Reviewed Original ResearchConceptsSciatic nerve blockTotal knee arthroplastyContinuous sciatic nerve blockPatient-controlled analgesiaNerve blockPain scoresStandardized mean differenceOpioid consumptionKnee arthroplastySingle-injection sciatic nerve blockControl groupSciatic-femoral nerve blockIntravenous opioid consumptionPostoperative analgesic benefitsPostoperative opioid consumptionIncidence of nauseaFemoral nerve blockLess pain scoresRandom-effects modelSystematic literature searchEvidence-based supportAnalgesic benefitHospital stayAcute painRandomized trialsDexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks
Zorrilla-Vaca A, Li J. Dexamethasone Injected Perineurally is More Effective than Administered Intravenously for Peripheral Nerve Blocks. The Clinical Journal Of Pain 2018, 34: 276-284. PMID: 28591086, DOI: 10.1097/ajp.0000000000000519.Peer-Reviewed Original ResearchConceptsPeripheral nerve blocksDuration of analgesiaPerineural dexamethasoneOpioid consumptionPain scoresPostoperative nauseaSensory blockNerve blockMotor block durationPain modulation mechanismsPerioperative pain controlPreservative-free dexamethasoneBetter analgesic effectDose of dexamethasoneTerms of prolongationSubgroup of studiesRandom-effects modelIntravenous dexamethasonePain controlAnalgesic effectMotor blockPostoperative outcomesAdministered IntravenouslyIntraoperative eventsSystemic absorption