Featured Publications
Improved hypertension control at six months using an adapted WHO HEARTS-based implementation strategy at a large urban HIV clinic in Uganda
Muddu M, Semitala FC, Kimera I, Mbuliro M, Ssennyonjo R, Kigozi SP, Katwesigye R, Ayebare F, Namugenyi C, Mugabe F, Mutungi G, Longenecker CT, Katahoire AR, Ssinabulya I, Schwartz JI. Improved hypertension control at six months using an adapted WHO HEARTS-based implementation strategy at a large urban HIV clinic in Uganda. BMC Health Services Research 2022, 22: 699. PMID: 35610717, PMCID: PMC9131679, DOI: 10.1186/s12913-022-08045-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood PressureFemaleHIV InfectionsHumansHypertensionMaleMiddle AgedUgandaWorld Health OrganizationConceptsLarge urban HIV clinicUrban HIV clinicHTN outcomesHIV clinicHypertension controlViral suppressionHIV outcomesHTN treatmentFurther implementation researchHIV viral suppressionProportion of patientsPre-post studyVaried clinical settingsAdult PLHIVBP controlHTN controlHTN screeningCare cascadeHIV careLifestyle counselingClinic visitsDiastolic BPHIV controlIndependent predictorsSystolic BPImpact of a COVID-19 National Lockdown on Integrated Care for Hypertension and HIV
Schwartz JI, Muddu M, Kimera I, Mbuliro M, Ssennyonjo R, Ssinabulya I, Semitala FC. Impact of a COVID-19 National Lockdown on Integrated Care for Hypertension and HIV. Global Heart 2021, 16: 9. PMID: 33598389, PMCID: PMC7863843, DOI: 10.5334/gh.928.Peer-Reviewed Original ResearchConceptsHealth facilitiesPublic health facilitiesCOVID-19 national lockdownHTN controlHIV clinicUgandan patientsClinical outcomesChronic conditionsHypertensionIntegrated careHIVCOVID-19National lockdownMovement restrictionsMedicineNationwide lockdownOutcomesAntiretroviralsLockdownPatientsClinicCohortMotor vehicle transportationCareIntegrated Hypertension and HIV Care Cascades in an HIV Treatment Program in Eastern Uganda: A Retrospective Cohort Study.
Muddu M, Tusubira AK, Sharma SK, Akiteng AR, Ssinabulya I, Schwartz JI. Integrated Hypertension and HIV Care Cascades in an HIV Treatment Program in Eastern Uganda: A Retrospective Cohort Study. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 81: 552-561. PMID: 31045649, PMCID: PMC6625912, DOI: 10.1097/qai.0000000000002067.Peer-Reviewed Original ResearchConceptsRetrospective cohort studyCare cascadeHIV careCohort studyHIV programsPrimary cardiovascular disease risk factorsCardiovascular disease risk factorsHIV care cascadeHIV care programsBlood pressure controlProportion of patientsDisease risk factorsHIV treatment programsViral load monitoringManagement of hypertensionHIV clinicEastern UgandaHIV treatmentRisk factorsCardiovascular diseaseHypertensionCare programPressure controlTreatment programHIV
2023
Diabetes mellitus care cascade among a cohort of persons living with HIV and hypertension in Uganda: A retrospective cohort study
Ambangira F, Sharman J, Muddu M, Kimera I, Namara D, Musimbaggo D, Namugenyi C, Ssenyonjo R, Mbuliro M, Katwesigye R, Schwartz J, Semitala F, Ssinabulya I. Diabetes mellitus care cascade among a cohort of persons living with HIV and hypertension in Uganda: A retrospective cohort study. International Journal Of STD & AIDS 2023, 34: 728-734. PMID: 37269360, DOI: 10.1177/09564624231179497.Peer-Reviewed Original ResearchConceptsDiabetes mellitusLarge urban HIV clinicNon-suppressed viral loadNon-communicable disease burdenUrban HIV clinicHIV care programsRetrospective cohort studyCohort of personsAppropriate diabetes careDiabetes mellitus careNon-communicable diseasesDual HIVCare cascadeHIV clinicCohort studyGlycaemic controlMedian ageViral loadRetrospective studyDiabetes careDisease burdenMellitus careCare programHIVHypertension
2022
The risk of hyperglycemia associated with use of dolutegravir among adults living with HIV in Kampala, Uganda: A case-control study
Namara D, Schwartz JI, Tusubira AK, McFarland W, Birungi C, Semitala FC, Muddu M. The risk of hyperglycemia associated with use of dolutegravir among adults living with HIV in Kampala, Uganda: A case-control study. International Journal Of STD & AIDS 2022, 33: 1158-1164. PMID: 36222490, PMCID: PMC9691558, DOI: 10.1177/09564624221129410.Peer-Reviewed Original ResearchMeSH KeywordsAdultCase-Control StudiesDiabetes MellitusHeterocyclic Compounds, 3-RingHIV InfectionsHumansMiddle AgedUgandaConceptsUse of dolutegravirRisk of hyperglycemiaCase-control studyDTG useDiabetes mellitusSubsequent diagnosisOral glucose tolerance testOdds of hyperglycemiaMedical record abstractionGlucose tolerance testMultivariable logistic regressionInterviewer-administered questionnaireNon-communicable diseasesTimes greater oddsDiagnosis of hyperglycemiaDTG exposureAlternate regimensAntiretroviral agentsRecord abstractionMultivariable analysisPotential confoundersPlasma glucoseTolerance testClinical dataHyperglycemiaIntegrated multi-month dispensing of antihypertensive and antiretroviral therapy to sustain hypertension and HIV control
Kimera ID, Namugenyi C, Schwartz JI, Musimbaggo DJ, Ssenyonjo R, Atukunda P, Mutungi G, Mugabe F, Ambangira F, Mbuliro M, Katwesigye R, Neupane D, Ssinabulya I, Semitala FC, Delles C, Muddu M. Integrated multi-month dispensing of antihypertensive and antiretroviral therapy to sustain hypertension and HIV control. Journal Of Human Hypertension 2022, 37: 213-219. PMID: 35246602, PMCID: PMC8896410, DOI: 10.1038/s41371-022-00655-3.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsAntihypertensive AgentsFemaleHIV InfectionsHumansHypertensionLongitudinal StudiesMaleMiddle AgedConceptsHIV viral suppressionHypertension controlViral suppressionBlood pressureElevated systolic blood pressureHIV treatment outcomesMean blood pressureProportion of patientsSystolic blood pressureRetention of patientsPatient-centered approachAntiretroviral therapyHIV clinicStable patientsHIV controlHIV treatmentMean ageTreatment outcomesHypertensionPatientsHealthcare providersClinical encountersMonthsBaselineLongitudinal study