2018
Antenatal depression, psychotropic medication use, and inflammation among pregnant women
Miller E, Grobman W, Culhane J, Adam E, Buss C, Entringer S, Miller G, Wadhwa P, Keenan-Devlin L, Borders A. Antenatal depression, psychotropic medication use, and inflammation among pregnant women. Archives Of Women's Mental Health 2018, 21: 785-790. PMID: 29862416, PMCID: PMC6240365, DOI: 10.1007/s00737-018-0855-9.Peer-Reviewed Original ResearchConceptsAntenatal depressive symptomsInflammatory biomarkersPregnant womenProspective multicenter observational studyCross-sectional secondary analysisContext of pharmacotherapyHigher TNFα levelsMulticenter observational studyEpidemiologic Studies Depression ScalePsychotropic medication useLower TNFαPre-existing high levelsAntenatal depressionMedication useSerum TNFαTNFα levelsWeeks' gestationSelf-reported useDepression screenPsychotropic medicationsTNFα concentrationsMedical recordsPoor responseTherapeutic responseObservational study
2003
Role of Psychosocial and Nutritional Stress on Poor Pregnancy Outcome
Hobel C, Culhane J. Role of Psychosocial and Nutritional Stress on Poor Pregnancy Outcome. Journal Of Nutrition 2003, 133: 1709s-1717s. PMID: 12730488, DOI: 10.1093/jn/133.5.1709s.Peer-Reviewed Original ResearchConceptsCorticotropin-releasing hormoneLow birth weightPreterm birthBirth weightAge-matched control subjectsRole of PsychosocialIndependent risk factorMaternal psychosocial stressPoor pregnancy outcomesStrenuous physical activityInitiation of laborElevated corticotropin-releasing hormonePlausible biological pathwaysPreterm laborPregnancy outcomesImmunomodulatory effectsControl subjectsEpidemiological evidenceRisk factorsClinical studiesPhysical activityEpidemiological dataMaternal stressPsychosocial stressClinical programs