1990
Dendritic action potentials activated by NMDA receptor-mediated EPSPs in CA1 hippocampal pyramidal cells
Poolos N, Kocsis J. Dendritic action potentials activated by NMDA receptor-mediated EPSPs in CA1 hippocampal pyramidal cells. Brain Research 1990, 524: 342-346. PMID: 1981329, DOI: 10.1016/0006-8993(90)90714-m.Peer-Reviewed Original ResearchConceptsExcitatory postsynaptic potentialsCA1 hippocampal pyramidal cellsDendritic action potentialsHippocampal pyramidal cellsPyramidal cellsRat CA1 hippocampal pyramidal cellsNMDA receptor-mediated excitatory postsynaptic potentialsAction potentialsDendritic excitatory postsynaptic potentialsN-methyl-D-aspartate receptorsPyramidal cell bodiesShort-term potentiationIntradendritic recordingsPostsynaptic potentialsSynaptic responsesDendritic arborsDendritic conductancesRepetitive stimulationDendritic spikesSomatic recordingsCell bodiesSubthreshold responsesMultiple sitesCellsRecordingsElevated extracellular potassium concentration enhances synaptic activation of N-methyl-d-aspartate receptors in hippocampus
Poolos N, Kocsis J. Elevated extracellular potassium concentration enhances synaptic activation of N-methyl-d-aspartate receptors in hippocampus. Brain Research 1990, 508: 7-12. PMID: 2159824, DOI: 10.1016/0006-8993(90)91110-3.Peer-Reviewed Original ResearchConceptsNMDA receptor activationNMDA receptorsReceptor activationNMDA receptor-mediated componentN-methyl-D-aspartate receptorsElevated extracellular potassium concentrationReceptor-mediated componentReceptor-mediated conductanceChannel blocker tetraethylammoniumCentral nervous systemExtracellular potassium concentrationExtracellular potassium ion concentrationSlowed repolarizationOrthodromic stimulationPotassium equilibrium potentialCA1 regionPyramidal cellsRat hippocampusSynaptic activationBlocker tetraethylammoniumPostsynaptic activityRepetitive stimulationNeuronal activityNervous systemReceptors
1988
Buspirone attenuates synaptic activation of hippocampal pyramidal cells
Mauk, Peroutka S, Kocsis J. Buspirone attenuates synaptic activation of hippocampal pyramidal cells. Journal Of Neuroscience 1988, 8: 1-11. PMID: 3339401, PMCID: PMC6569355, DOI: 10.1523/jneurosci.08-01-00001.1988.Peer-Reviewed Original ResearchConceptsExcitatory postsynaptic potentialsPyramidal cellsStratum radiatumSynaptic activationAfferent fibersHippocampal CA1 pyramidal cellsInput resistanceStimulation of afferentsEffects of buspironeCA1 pyramidal cellsHippocampal pyramidal cellsPostsynaptic potentialsPresynaptic fibersConduction slowingFiber excitabilitySpike activityAnxiolytic agentsBuspironeRefractory periodRadiatumRapid hyperpolarizationReceptor sitesMeasurable effectExcitabilityMembrane potential
1987
Activity-evoked increases in extracellular potassium modulate presynaptic excitability in the CA1 region of the hippocampus
Poolos N, Mauk M, Kocsis J. Activity-evoked increases in extracellular potassium modulate presynaptic excitability in the CA1 region of the hippocampus. Journal Of Neurophysiology 1987, 58: 404-416. PMID: 3655875, DOI: 10.1152/jn.1987.58.2.404.Peer-Reviewed Original ResearchConceptsEnd of stimulationConduction velocityRepetitive stimulationCA1 afferentsStratum radiatumCA1 regionPostsynaptic elementsPostsynaptic activityBiphasic changeRat hippocampal slice preparationCompound action potentialHippocampal slice preparationCharacteristic field potentialHigher stimulation frequenciesPostsynaptic modulationPresynaptic volleyKynurenic acidPyramidal cellsSlice preparationPresynaptic axonsPresynaptic excitabilitySynaptic transmissionConduction blockIon-sensitive microelectrodesPostsynaptic activation