1998
A summary of mechanistic hypotheses of gabapentin pharmacology
Taylor C, Gee N, Su T, Kocsis J, Welty D, Brown J, Dooley D, Boden P, Singh L. A summary of mechanistic hypotheses of gabapentin pharmacology. Epilepsy Research 1998, 29: 233-249. PMID: 9551785, DOI: 10.1016/s0920-1211(97)00084-3.Peer-Reviewed Original ResearchConceptsAmyotrophic lateral sclerosisNon-vesicular GABA releaseCellular mechanismsVoltage-sensitive Ca2Specific amino acid transportersGabapentin bindsGABA releaseNeuronal deathElectrophysiology resultsAnticonvulsant drugsLateral sclerosisNeuroprotective activityNeurobehavioral actionsPharmacological actionsGabapentinAnimal modelsHuman whole bloodBrain tissueMonoamine neurotransmittersAmino acid transportersWhole bloodAcid transportersAuxiliary subunitsPharmacologyRate of synthesis
1996
Chapter 5 Cellular mechanisms regulating neurite initiation
Lankford K, Kenney A, Kocsis J. Chapter 5 Cellular mechanisms regulating neurite initiation. Progress In Brain Research 1996, 108: 55-81. PMID: 8979794, DOI: 10.1016/s0079-6123(08)62532-7.Peer-Reviewed Original ResearchConceptsNeurite initiationImmediate early genesGrowth cone behaviorEarly genesNeurite formationCell typesCellular mechanismsNeurite outgrowthCellular changesCone behaviorCritical roleMacromolecular levelOutgrowthInitial eventPossible roleMorphological changesProtein 43Complex processMorphogenesisGenesMicrotubulesInitiationProteinCalcium transientsMechanism