2001
Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato.
Castro M, Nicholson W, Kramer V, Childs J. Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato. American Journal Of Tropical Medicine And Hygiene 2001, 65: 261-7. PMID: 11693866, DOI: 10.4269/ajtmh.2001.65.261.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BacterialArachnid VectorsBase SequenceBorrelia burgdorferiCaliforniaDisease ReservoirsDNA, BacterialEhrlichiaEhrlichiosisFemaleFluorescent Antibody Technique, IndirectHeat-Shock ProteinsHumansIxodesMaleMicePolymerase Chain ReactionRatsRodent DiseasesSeasonsSeroepidemiologic StudiesSigmodontinaeZoonosesConceptsPolymerase chain reaction testingGroESL heat shock operonPersistent infectionReaction testingRatsE. phagocytophilaLyme diseaseBorrelia burgdorferiMiceSeropositive animalsDusky-footed wood ratsPCRWood ratsSeroreversionSensu latoSeroconversionSeropositiveBiopsySerologySeroreactivityInfectionDiseaseBloodAdult Ixodes pacificus CooleySerumInfections with Ehrlichia chaffeensis and Ehrlichia ewingii in Persons Coinfected with Human Immunodeficiency Virus
Paddock C, Folk S, Shore G, Machado L, Huycke M, Slater L, Liddell A, Buller R, Storch G, Monson T, Rimland D, Sumner J, Singleton J, Bloch K, Tang Y, Standaert S, Childs J. Infections with Ehrlichia chaffeensis and Ehrlichia ewingii in Persons Coinfected with Human Immunodeficiency Virus. Clinical Infectious Diseases 2001, 33: 1586-1594. PMID: 11568857, DOI: 10.1086/323981.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusImmunodeficiency virusE. ewingiiE. chaffeensisCases of ehrlichiosisDiagnosis of ehrlichiosisT-lymphocyte countsCells/microL.Ehrlichia ewingiiEhrlichia chaffeensisLife-threatening illnessLymphocyte countClinical courseHIV infectionMedical managementPatient cohortSevere manifestationsPatientsLaboratory evaluationEhrlichiosisChaffeensisInfectionEwingiiMultiple factorsVirusProspective Assessment of the Etiology of Acute Febrile Illness after a Tick Bite in Slovenia
Lotrič-Furlan S, Petrovec M, Avsic-Zupanc T, Nicholson W, Sumner J, Childs J, Strle F. Prospective Assessment of the Etiology of Acute Febrile Illness after a Tick Bite in Slovenia. Clinical Infectious Diseases 2001, 33: 503-510. PMID: 11462187, DOI: 10.1086/322586.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAnimalsBites and StingsBorrelia burgdorferi GroupCohort StudiesEhrlichiaEhrlichia chaffeensisEhrlichiosisEncephalitis Viruses, Tick-BorneEncephalitis, Tick-BorneFemaleFeverHumansLyme DiseaseMaleMiddle AgedProspective StudiesSloveniaTick-Borne DiseasesTicksConceptsFebrile illnessTick biteEhrlichia phagocytophila infectionAcute febrile illnessTickborne diseasesEvidence of infectionBorrelia burgdorferi sensu latoMeningeal involvementProspective studyClinical criteriaBurgdorferi sensu latoTickborne encephalitisProspective assessmentPatientsLaboratory evidenceImportant causeBacterial infectionsIllnessLyme borreliosisInfectionDiseaseResidents of SloveniaEtiologyBiteEncephalitisUrban Zoonoses Caused by Bartonella, Coxiella, Ehrlichia, and Rickettsia Species
Comer J, Paddock C, Childs J. Urban Zoonoses Caused by Bartonella, Coxiella, Ehrlichia, and Rickettsia Species. Vector-Borne And Zoonotic Diseases 2001, 1: 91-118. PMID: 12653141, DOI: 10.1089/153036601316977714.Peer-Reviewed Original ResearchFort Chaffee Revisited: The Epidemiology of Tick-Borne Rickettsial and Ehrlichial Diseases at a Natural Focus
McCall C, Curns A, Rotz L, Singleton J, Treadwell T, Comer J, Nicholson W, Olson J, Childs J. Fort Chaffee Revisited: The Epidemiology of Tick-Borne Rickettsial and Ehrlichial Diseases at a Natural Focus. Vector-Borne And Zoonotic Diseases 2001, 1: 119-127. PMID: 12653142, DOI: 10.1089/153036601316977723.Peer-Reviewed Original ResearchConceptsTick-borne pathogensSerum samplesRetrospective cohort studyDetectable antibody titersPrimary risk factorRisk of transmissionFort ChaffeeFever group rickettsiaeCompatible illnessReactive EIAsTick-borne diseaseCohort studyDoxycycline useAntibody titersRisk factorsTick biteEhrlichial diseasesGroup rickettsiaeDiseaseMore pathogensProbable diseaseSeropositivityIllnessEhrlichia speciesInfection
1999
Dusky-Footed Wood Rats (Neotoma fuscipes) as Reservoirs of Granulocytic Ehrlichiae (Rickettsiales: Ehrlichieae) in Northern California
Nicholson W, Castro M, Kramer V, Sumner J, Childs J. Dusky-Footed Wood Rats (Neotoma fuscipes) as Reservoirs of Granulocytic Ehrlichiae (Rickettsiales: Ehrlichieae) in Northern California. Journal Of Clinical Microbiology 1999, 37: 3323-3327. PMID: 10488199, PMCID: PMC85556, DOI: 10.1128/jcm.37.10.3323-3327.1999.Peer-Reviewed Original ResearchConceptsBlood samplesBlood specimensDusky-footed wood ratsConcurrent high prevalenceSeronegative blood samplesHuman granulocytic ehrlichiosisGroESL heat shock operonGranulocytic ehrlichiaePCR-positive animalsPCR positivityHigh prevalencePCR-positive ticksSeropositive specimensRat blood samplesRatsGranulocytic ehrlichiosisEhrlichial DNAPacificus adultsEhrlichia equiEhrlichial agentsMicePCR assaysAdultsWood ratsRodentsIdentity of Ehrlichial DNA Sequences Derived from Ixodes ricinus Ticks with Those Obtained from Patients with Human Granulocytic Ehrlichiosis in Slovenia
Petrovec M, Sumner J, Nicholson W, Childs J, Strle F, Barlič J, Lotrič-Furlan S, AvšičŽupanc T. Identity of Ehrlichial DNA Sequences Derived from Ixodes ricinus Ticks with Those Obtained from Patients with Human Granulocytic Ehrlichiosis in Slovenia. Journal Of Clinical Microbiology 1999, 37: 209-210. PMID: 9854093, PMCID: PMC84210, DOI: 10.1128/jcm.37.1.209-210.1999.Peer-Reviewed Original Research
1998
Human Granulocytic Ehrlichiosis in Europe: Clinical and Laboratory Findings for Four Patients from Slovenia
Lotrič-Furlan S, Petrovec M, Zupanc T, Nicholson W, Sumner J, Childs J, Strle F. Human Granulocytic Ehrlichiosis in Europe: Clinical and Laboratory Findings for Four Patients from Slovenia. Clinical Infectious Diseases 1998, 27: 424-428. PMID: 9770134, DOI: 10.1086/514683.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisHGE agentFebrile illnessLaboratory findingsTick biteAcute human granulocytic ehrlichiosisGranulocytic ehrlichiosisTick-borne diseaseAcute infectionAntibiotic therapyDisease coursePolymerase chain reaction analysisClinical featuresDetectable antibodiesDifferential diagnosisFirst visitChain reaction analysisPatientsHigh titersIllnessEhrlichial organismsEhrlichiosisAntibodiesBiteUnited StatesSerologic Evidence of Infection with Ehrlichia spp. in Wild Rodents (Muridae: Sigmodontinae) in the United States
Nicholson W, Muir S, Sumner J, Childs J. Serologic Evidence of Infection with Ehrlichia spp. in Wild Rodents (Muridae: Sigmodontinae) in the United States. Journal Of Clinical Microbiology 1998, 36: 695-700. PMID: 9508298, PMCID: PMC104611, DOI: 10.1128/jcm.36.3.695-700.1998.Peer-Reviewed Original ResearchRetrospective Serosurvey for Human Granulocytic Ehrlichiosis Agent in Urban White-footed Mice from Maryland
Bunnell J, Stephen D, Childs J, Glass G. Retrospective Serosurvey for Human Granulocytic Ehrlichiosis Agent in Urban White-footed Mice from Maryland. Journal Of Wildlife Diseases 1998, 34: 179-181. PMID: 9476244, DOI: 10.7589/0090-3558-34.1.179.Peer-Reviewed Original Research
1997
An indirect immunofluorescence assay using a cell culture-derived antigen for detection of antibodies to the agent of human granulocytic ehrlichiosis
Nicholson W, Comer J, Sumner J, Gingrich-Baker C, Coughlin R, Magnarelli L, Olson J, Childs J. An indirect immunofluorescence assay using a cell culture-derived antigen for detection of antibodies to the agent of human granulocytic ehrlichiosis. Journal Of Clinical Microbiology 1997, 35: 1510-1516. PMID: 9163471, PMCID: PMC229776, DOI: 10.1128/jcm.35.6.1510-1516.1997.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisCell culture-derived antigenHuman antibodiesGranulocytic ehrlichiosisIndirect immunofluorescenceHGE agentAnimal-derived antigensDetection of antibodiesTick-derived isolatesPromyelocytic leukemia cell lineAntigen presentationHuman promyelocytic leukemia cell lineHealthy individualsLeukemia cell linesHGE patientsSera reactiveEhrlichia phagocytophilaHigh titersAntigenImmunofluorescence methodE. equiEhrlichia equiRoutine testingAntibodiesSpecific antibodies
1994
WHITE-TAILED DEER AS A POTENTIAL RESERVOIR OF EHRLICHIA SPP.
Dawson J, Childs J, Biggie K, Moore C, Stallknecht D, Shaddock J, Bouseman J, Hofmeister E, Olson J. WHITE-TAILED DEER AS A POTENTIAL RESERVOIR OF EHRLICHIA SPP. Journal Of Wildlife Diseases 1994, 30: 162-168. PMID: 8028099, DOI: 10.7589/0090-3558-30.2.162.Peer-Reviewed Original Research
1993
Amblyomma americanum: a potential vector of human ehrlichiosis.
Anderson B, Sims K, Olson J, Childs J, Piesman J, Happ C, Maupin G, Johnson B. Amblyomma americanum: a potential vector of human ehrlichiosis. American Journal Of Tropical Medicine And Hygiene 1993, 49: 239-44. PMID: 8357086, DOI: 10.4269/ajtmh.1993.49.239.Peer-Reviewed Original Research