2001
Evidence of rodent-associated Bartonella and Rickettsia infections among intravenous drug users from Central and East Harlem, New York City.
Comer J, Diaz T, Vlahov D, Monterroso E, Childs J. Evidence of rodent-associated Bartonella and Rickettsia infections among intravenous drug users from Central and East Harlem, New York City. American Journal Of Tropical Medicine And Hygiene 2001, 65: 855-60. PMID: 11791987, DOI: 10.4269/ajtmh.2001.65.855.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnimalsAntibodies, BacterialBartonellaBartonella InfectionsCohort StudiesCross ReactionsFemaleFluorescent Antibody Technique, IndirectHIV SeropositivityHumansMaleNew York CityPrevalenceRatsRickettsiaRickettsia InfectionsSubstance Abuse, IntravenousSurveys and QuestionnairesUrban HealthConceptsInjection drug usersDrug usersGroup rickettsiaeSerum samplesIntravenous drug usersCross-adsorption studiesEast HarlemR. akari infectionPrimary etiologic agentTyphus group rickettsiaeFever group rickettsiaeIDU populationHigh prevalenceEtiologic agentNew York CityRickettsia akariBartonella henselaeAntigenTesting panelsRickettsia typhiB. henselaeBartonella quintanaR. rickettsiiRickettsia infectionR. akariFort Chaffee Revisited: The Epidemiology of Tick-Borne Rickettsial and Ehrlichial Diseases at a Natural Focus
McCall C, Curns A, Rotz L, Singleton J, Treadwell T, Comer J, Nicholson W, Olson J, Childs J. Fort Chaffee Revisited: The Epidemiology of Tick-Borne Rickettsial and Ehrlichial Diseases at a Natural Focus. Vector-Borne And Zoonotic Diseases 2001, 1: 119-127. PMID: 12653142, DOI: 10.1089/153036601316977723.Peer-Reviewed Original ResearchConceptsTick-borne pathogensSerum samplesRetrospective cohort studyDetectable antibody titersPrimary risk factorRisk of transmissionFort ChaffeeFever group rickettsiaeCompatible illnessReactive EIAsTick-borne diseaseCohort studyDoxycycline useAntibody titersRisk factorsTick biteEhrlichial diseasesGroup rickettsiaeDiseaseMore pathogensProbable diseaseSeropositivityIllnessEhrlichia speciesInfectionSerologic evidence of Rickettsia akari infection among dogs in a metropolitan city.
Comer J, Vargas M, Poshni I, Childs J. Serologic evidence of Rickettsia akari infection among dogs in a metropolitan city. Journal Of The American Veterinary Medical Association 2001, 218: 1780-2. PMID: 11394829, DOI: 10.2460/javma.2001.218.1780.Peer-Reviewed Original ResearchConceptsIndirect immunofluorescence antibodyEnzyme immunoassaySerum samplesPossible risk factorsFever group rickettsiaeClinical illnessRoutine careSerologic evidenceSeropositive dogsRisk factorsTime serum samplesIFA testingClinical relevanceImmunofluorescence antibodySerologic surveyRickettsia akariInfectionGroup rickettsiaeDogsTitersCausative agentVeterinary clinicsFurther studiesDog ownersTick infestation
2000
DETECTION OF ANTIBODIES REACTIVE WITH EHRLICHIA CHAFFEENSIS IN THE RACCOON
Comer J, Nicholson W, Paddock C, Sumner J, Childs J. DETECTION OF ANTIBODIES REACTIVE WITH EHRLICHIA CHAFFEENSIS IN THE RACCOON. Journal Of Wildlife Diseases 2000, 36: 705-712. PMID: 11085432, DOI: 10.7589/0090-3558-36.4.705.Peer-Reviewed Original ResearchPrevalence of Antibody to Hepatitis E Virus among Rodents in the United States
Favorov M, Kosoy M, Tsarev S, Childs J, Margolis H. Prevalence of Antibody to Hepatitis E Virus among Rodents in the United States. The Journal Of Infectious Diseases 2000, 181: 449-455. PMID: 10669325, DOI: 10.1086/315273.Peer-Reviewed Original Research
1999
Outcome of Diagnostic Tests Using Samples from Patients with Culture-Proven Human Monocytic Ehrlichiosis: Implications for Surveillance
Childs J, Sumner J, Nicholson W, Massung R, Standaert S, Paddock C. Outcome of Diagnostic Tests Using Samples from Patients with Culture-Proven Human Monocytic Ehrlichiosis: Implications for Surveillance. Journal Of Clinical Microbiology 1999, 37: 2997-3000. PMID: 10449489, PMCID: PMC85432, DOI: 10.1128/jcm.37.9.2997-3000.1999.Peer-Reviewed Original ResearchConceptsHuman monocytic ehrlichiosisDiagnosis of HMEConvalescent-phase serum samplesMonocytic ehrlichiosisDetection of morulaeInitial clinical presentationCulture-proven casesE. chaffeensis antigenWhole blood specimensCompatible illnessClinical presentationInitial presentationSerologic responseCase definitionHME patientsBlood specimensImmunoglobulin MPatientsBlood smearsIndirect immunofluorescenceEhrlichial DNADiagnostic testsSerum samplesProbable diseaseEhrlichia chaffeensisSerologic evidence of rickettsialpox (Rickettsia akari) infection among intravenous drug users in inner-city Baltimore, Maryland.
Comer J, Tzianabos T, Flynn C, Vlahov D, Childs J. Serologic evidence of rickettsialpox (Rickettsia akari) infection among intravenous drug users in inner-city Baltimore, Maryland. American Journal Of Tropical Medicine And Hygiene 1999, 60: 894-8. PMID: 10403316, DOI: 10.4269/ajtmh.1999.60.894.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, BacterialBaltimoreCohort StudiesCross ReactionsDrinkingFemaleFluorescent Antibody Technique, IndirectHIV SeropositivityHumansIll-Housed PersonsMaleRickettsiaRickettsia InfectionsRickettsia rickettsiiRisk FactorsSeroepidemiologic StudiesSubstance Abuse, IntravenousUrban PopulationConceptsIntravenous drug usersInner-city BaltimoreDrug usersSerologic evidenceSerum samplesAcute febrile illnessR. rickettsiiR. akariHuman immunodeficiency virusSignificant risk factorsSignificant inverse associationCross-adsorption studiesPresence of antibodiesSingle serum sampleR. akari infectionFrequency of injectionsFever group rickettsiaeFebrile illnessUndetermined etiologyImmunodeficiency virusInverse associationRisk factorsGroup-specific antibodiesDrug useHigh titersFamily Cluster of Rocky Mountain Spotted Fever
Jones T, Craig A, Paddock C, McKechnie D, Childs J, Zaki S, Schaffner W. Family Cluster of Rocky Mountain Spotted Fever. Clinical Infectious Diseases 1999, 28: 853-859. PMID: 10825050, DOI: 10.1086/515213.Peer-Reviewed Original ResearchSerologic Testing for Human Granulocytic Ehrlichiosis at a National Referral Center
Comer J, Nicholson W, Olson J, Childs J. Serologic Testing for Human Granulocytic Ehrlichiosis at a National Referral Center. Journal Of Clinical Microbiology 1999, 37: 558-564. PMID: 9986812, PMCID: PMC84468, DOI: 10.1128/jcm.37.3.558-564.1999.Peer-Reviewed Original ResearchConceptsHGE agentSerum samplesNational referral centerE. chaffeensis antigenSpecific etiologic agentState health departmentsE. chaffeensisHuman granulocytic ehrlichiosis (HGE) agentHuman granulocytic ehrlichiosisHuman monocytic ehrlichiosisReferral centerSerologic testingEhrlichial antigenAverage ageHealth departmentsHuman ehrlichiosisPatientsEtiologic agentProbable casesHigh titersIll individualsGranulocytic ehrlichiosisDisease controlIndirect immunofluorescenceMonocytic ehrlichiosisDiagnosis of Human Ehrlichiosis by PCR Assay of Acute-Phase Serum
Comer J, Nicholson W, Sumner J, Olson J, Childs J. Diagnosis of Human Ehrlichiosis by PCR Assay of Acute-Phase Serum. Journal Of Clinical Microbiology 1999, 37: 31-34. PMID: 9854059, PMCID: PMC84159, DOI: 10.1128/jcm.37.1.31-34.1999.Peer-Reviewed Original ResearchConceptsDetermination of etiologyAcute-phase seraHuman granulocytic ehrlichiosisSerologic testingHuman ehrlichiosisAcute-phase serum samplesEarly detectionWhole blood specimensPCR assaysBlood specimensPCR testingEtiologic agentGranulocytic ehrlichiosisEtiologyHGE agentSimilar titersSerum samplesExposure historyTitersEhrlichia chaffeensisEhrlichiosisFourfold differenceE. chaffeensisSerumAntibodies
1998
Retrospective Serosurvey for Human Granulocytic Ehrlichiosis Agent in Urban White-footed Mice from Maryland
Bunnell J, Stephen D, Childs J, Glass G. Retrospective Serosurvey for Human Granulocytic Ehrlichiosis Agent in Urban White-footed Mice from Maryland. Journal Of Wildlife Diseases 1998, 34: 179-181. PMID: 9476244, DOI: 10.7589/0090-3558-34.1.179.Peer-Reviewed Original Research
1997
Survey of veterinary professionals and other veterinary conference attendees for antibodies to Bartonella henselae and B quintana.
Noah D, Kramer C, Verbsky M, Rooney J, Smith K, Childs J. Survey of veterinary professionals and other veterinary conference attendees for antibodies to Bartonella henselae and B quintana. Journal Of The American Veterinary Medical Association 1997, 210: 342-4. PMID: 9057914, DOI: 10.2460/javma.1997.210.03.342.Peer-Reviewed Original ResearchConceptsCat-scratch diseaseB quintanaBartonella henselaeOccupational groupsVeterinary techniciansIllness consistentPrevious diagnosisEpidemiologic characteristicsPotential confoundersOverall seroprevalenceUnknown prevalenceB henselaeEpidemiologic SurveyHospital staffCat ownershipSp infectionExposure informationSerum samplesVeterinary conferencesHenselaeSeropositivitySpecies of BartonellaSeroprevalenceInfectionUnknown duration
1996
Antibodies to Bartonella Species in Inner-city Intravenous Drug Users in Baltimore, Md
Comer J, Flynn C, Regnery R, Vlahov D, Childs J. Antibodies to Bartonella Species in Inner-city Intravenous Drug Users in Baltimore, Md. JAMA Internal Medicine 1996, 156: 2491-2495. PMID: 8944742, DOI: 10.1001/archinte.1996.00440200111014.Peer-Reviewed Original ResearchConceptsIntravenous drug usersHuman immunodeficiency virus statusB quintanaRisk factorsDrug usersB henselaeDrug useVirus statusHuman immunodeficiency virus-seropositive individualsHuman immunodeficiency virus (HIV) infectionSerum samplesImmunodeficiency virus infectionAvailable serum samplesSignificant risk factorsBehavioral risk factorsPossible risk factorsSignificant inverse associationIndirect immunofluorescent antibodyFrequency of injectionsUrban transmission cyclesBartonella speciesBartonella organismsMode of transmissionCurrent natural historyImmunodeficiency syndrome
1995
Use of Bartonella Antigens for Serologic Diagnosis of Cat-scratch Disease at a National Referral Center
Dalton M, Robinson L, Cooper J, Regnery R, Olson J, Childs J. Use of Bartonella Antigens for Serologic Diagnosis of Cat-scratch Disease at a National Referral Center. JAMA Internal Medicine 1995, 155: 1670-1676. PMID: 7542443, DOI: 10.1001/archinte.1995.00430150164017.Peer-Reviewed Original ResearchConceptsCat-scratch diseaseIndirect fluorescent antibodySerum samplesB henselaeFluorescent antibodyNational referral centerStrict clinical definitionsUse of antigensReferral centerCat contactRegional adenopathyCat scratchClinical historyFourfold riseB quintanaBasis of causeClinical definitionClinical informationDiagnostic criteriaPatientsSerologic diagnosisDisease controlBartonella henselaeCat ageDisease