2001
Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato.
Castro M, Nicholson W, Kramer V, Childs J. Persistent infection in Neotoma fuscipes (Muridae: Sigmodontinae) with Ehrlichia phagocytophila sensu lato. American Journal Of Tropical Medicine And Hygiene 2001, 65: 261-7. PMID: 11693866, DOI: 10.4269/ajtmh.2001.65.261.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BacterialArachnid VectorsBase SequenceBorrelia burgdorferiCaliforniaDisease ReservoirsDNA, BacterialEhrlichiaEhrlichiosisFemaleFluorescent Antibody Technique, IndirectHeat-Shock ProteinsHumansIxodesMaleMicePolymerase Chain ReactionRatsRodent DiseasesSeasonsSeroepidemiologic StudiesSigmodontinaeZoonosesConceptsPolymerase chain reaction testingGroESL heat shock operonPersistent infectionReaction testingRatsE. phagocytophilaLyme diseaseBorrelia burgdorferiMiceSeropositive animalsDusky-footed wood ratsPCRWood ratsSeroreversionSensu latoSeroconversionSeropositiveBiopsySerologySeroreactivityInfectionDiseaseBloodAdult Ixodes pacificus CooleySerum
1999
Population Dynamics of a Naturally Occurring Heterogeneous Mixture of Borrelia burgdorferiClones
Hofmeister E, Glass G, Childs J, Persing D. Population Dynamics of a Naturally Occurring Heterogeneous Mixture of Borrelia burgdorferiClones. Infection And Immunity 1999, 67: 5709-5716. PMID: 10531219, PMCID: PMC96945, DOI: 10.1128/iai.67.11.5709-5716.1999.Peer-Reviewed Original ResearchConceptsC3H/HeJ miceC.B-17 miceLarval Ixodes scapularis ticksMajority of miceB. burgdorferiInfected nymphal ticksIxodes scapularis ticksBurgdorferi antibodiesSecondary challengeHeJ micePrimary isolatesSequential isolatesC3H miceSequential infectionMiceMonoclonal antibodiesBorrelia burgdorferiC expressionScapularis ticksClonal dominanceUnique isolatesMacrorestriction analysisOspC proteinsClonal groupsEnzootic siteLongitudinal study of infection with Borrelia burgdorferi in a population of Peromyscus leucopus at a Lyme disease-enzootic site in Maryland.
Hofmeister E, Ellis B, Glass G, Childs J. Longitudinal study of infection with Borrelia burgdorferi in a population of Peromyscus leucopus at a Lyme disease-enzootic site in Maryland. American Journal Of Tropical Medicine And Hygiene 1999, 60: 598-609. PMID: 10348235, DOI: 10.4269/ajtmh.1999.60.598.Peer-Reviewed Original ResearchConceptsPolymerase chain reactionB. burgdorferiJuvenile miceCross-sectional sampleEar tissueBorrelia burgdorferi infectionIxodes scapularis ticksInfected miceSusceptible miceChronic infectionOverall prevalenceIncidence rateBurgdorferi infectionHigh riskLower riskInfectionMiceInfected ticksLongitudinal sampleBorrelia burgdorferiScapularis ticksChain reactionBurgdorferiLongitudinal studyIndirect transmission
1995
Analysis of Borrelia burgdorferi Sequentially Isolated from Peromyscus leucopus Captured at a Lyme Disease Enzootic Site
Hofmeister E, Childs J. Analysis of Borrelia burgdorferi Sequentially Isolated from Peromyscus leucopus Captured at a Lyme Disease Enzootic Site. The Journal Of Infectious Diseases 1995, 172: 462-469. PMID: 7622890, DOI: 10.1093/infdis/172.2.462.Peer-Reviewed Original ResearchEAR BIOPSY LOCATION INFLUENCES DETECTION OF BORRELIA BURGDORFERI BY PCR, BUT NOT BY CULTURE IN NATURALLY INFECTED PEROMYSCUS LEUCOPUS
Hofmeister E, Childs J. EAR BIOPSY LOCATION INFLUENCES DETECTION OF BORRELIA BURGDORFERI BY PCR, BUT NOT BY CULTURE IN NATURALLY INFECTED PEROMYSCUS LEUCOPUS. Journal Of Wildlife Diseases 1995, 31: 345-351. PMID: 8592355, DOI: 10.7589/0090-3558-31.3.345.Peer-Reviewed Original ResearchConceptsEar biopsy samplesPolymerase chain reactionBiopsy samplesBiopsy locationB. burgdorferiBorrelia burgdorferiInfected micePeripheral samplesIndividual miceInfection statusMore tissue samplesMiceTissue samplesHigh concordanceChain reactionOrgan cultureBurgdorferiGreater frequencyEar samplesWhite-footed miceEnzootic areaEarCentral sample
1994
Longitudinal Study of Borrelia burgdorferi Infection in New Jersey Outdoor Workers, 1988–1991
Schwartz B, Goldstein M, Childs J. Longitudinal Study of Borrelia burgdorferi Infection in New Jersey Outdoor Workers, 1988–1991. American Journal Of Epidemiology 1994, 139: 504-512. PMID: 8154474, DOI: 10.1093/oxfordjournals.aje.a117033.Peer-Reviewed Original ResearchConceptsRisk factorsRural residenceSeroconversion of antibodiesBorrelia burgdorferi infectionLyme disease seroprevalenceAntibody seropositivitySerologic statusOdds ratioBurgdorferi infectionTick exposureSeroconversionElevated riskHigh riskOutdoor workersAnnual questionnairesMedical problemsLyme diseaseDisease seroprevalenceSeroprevalenceBorrelia burgdorferiLongitudinal studySeropositivityPet ownershipRural residentsRisk
1993
Antibodies to Borrelia burgdorferi and tick salivary gland proteins in New Jersey outdoor workers.
Schwartz B, Goldstein M, Childs J. Antibodies to Borrelia burgdorferi and tick salivary gland proteins in New Jersey outdoor workers. American Journal Of Public Health 1993, 83: 1746-8. PMID: 8259808, PMCID: PMC1694949, DOI: 10.2105/ajph.83.12.1746.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsAntibodiesAntibodies, BacterialArachnid VectorsBorrelia burgdorferi GroupCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleFollow-Up StudiesHumansLyme DiseaseMaleNew JerseyOccupational DiseasesPrevalenceRisk FactorsSalivary Proteins and PeptidesSeroepidemiologic StudiesSurveys and QuestionnairesTicksWorkplaceConceptsOutdoor workersBorrelia burgdorferiCross-sectional studyB. burgdorferi infectionSecond cross-sectional studyEnzyme-linked immunosorbentLyme disease seroprevalenceAntibody seropositivitySalivary gland proteinsBurgdorferi infectionTick exposureHigh riskLyme diseaseDisease seroprevalenceAntibodiesBurgdorferiGland proteinsSeropositivitySeroprevalenceInfectionPrevalenceDiseaseImmunosorbentWorkers