2000
Prevalence of Antibody to Hepatitis E Virus among Rodents in the United States
Favorov M, Kosoy M, Tsarev S, Childs J, Margolis H. Prevalence of Antibody to Hepatitis E Virus among Rodents in the United States. The Journal Of Infectious Diseases 2000, 181: 449-455. PMID: 10669325, DOI: 10.1086/315273.Peer-Reviewed Original Research
1999
Family Cluster of Rocky Mountain Spotted Fever
Jones T, Craig A, Paddock C, McKechnie D, Childs J, Zaki S, Schaffner W. Family Cluster of Rocky Mountain Spotted Fever. Clinical Infectious Diseases 1999, 28: 853-859. PMID: 10825050, DOI: 10.1086/515213.Peer-Reviewed Original ResearchDiagnosis of Human Ehrlichiosis by PCR Assay of Acute-Phase Serum
Comer J, Nicholson W, Sumner J, Olson J, Childs J. Diagnosis of Human Ehrlichiosis by PCR Assay of Acute-Phase Serum. Journal Of Clinical Microbiology 1999, 37: 31-34. PMID: 9854059, PMCID: PMC84159, DOI: 10.1128/jcm.37.1.31-34.1999.Peer-Reviewed Original ResearchConceptsDetermination of etiologyAcute-phase seraHuman granulocytic ehrlichiosisSerologic testingHuman ehrlichiosisAcute-phase serum samplesEarly detectionWhole blood specimensPCR assaysBlood specimensPCR testingEtiologic agentGranulocytic ehrlichiosisEtiologyHGE agentSimilar titersSerum samplesExposure historyTitersEhrlichia chaffeensisEhrlichiosisFourfold differenceE. chaffeensisSerumAntibodies
1998
Human Granulocytic Ehrlichiosis in Europe: Clinical and Laboratory Findings for Four Patients from Slovenia
Lotrič-Furlan S, Petrovec M, Zupanc T, Nicholson W, Sumner J, Childs J, Strle F. Human Granulocytic Ehrlichiosis in Europe: Clinical and Laboratory Findings for Four Patients from Slovenia. Clinical Infectious Diseases 1998, 27: 424-428. PMID: 9770134, DOI: 10.1086/514683.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisHGE agentFebrile illnessLaboratory findingsTick biteAcute human granulocytic ehrlichiosisGranulocytic ehrlichiosisTick-borne diseaseAcute infectionAntibiotic therapyDisease coursePolymerase chain reaction analysisClinical featuresDetectable antibodiesDifferential diagnosisFirst visitChain reaction analysisPatientsHigh titersIllnessEhrlichial organismsEhrlichiosisAntibodiesBiteUnited StatesISOLATION OF BARTONELLA SPP. FROM EMBRYOS AND NEONATES OF NATURALLY INFECTED RODENTS
Kosoy M, Regnery R, Kosaya O, Jones D, Marston E, Childs J. ISOLATION OF BARTONELLA SPP. FROM EMBRYOS AND NEONATES OF NATURALLY INFECTED RODENTS. Journal Of Wildlife Diseases 1998, 34: 305-309. PMID: 9577777, DOI: 10.7589/0090-3558-34.2.305.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornAntibodies, BacterialBacteremiaBartonellaBartonella InfectionsCitrate (si)-SynthaseColony Count, MicrobialEmbryo, MammalianFemaleFetal DiseasesInfectious Disease Transmission, VerticalPeromyscusPhylogenyPlacentaPregnancyPregnancy Complications, InfectiousRodent DiseasesSigmodontinae
1997
A survey for antibodies to Lassa virus among health workers in Nigeria
Bajani M, Tomori O, Rollin P, Harry T, Bukbuk N, Wilson L, Childs J, Peters C, Ksiazek T. A survey for antibodies to Lassa virus among health workers in Nigeria. Transactions Of The Royal Society Of Tropical Medicine And Hygiene 1997, 91: 379-381. PMID: 9373625, DOI: 10.1016/s0035-9203(97)90247-9.Peer-Reviewed Original ResearchConceptsHealth workersAntibody prevalenceHealth facilitiesSecondary health facilitiesVirus IgM antibodiesImmunoglobulin G antibodiesEnzyme-linked immunosorbentTertiary centerSpecific IgMIgM antibodiesRecent infectionHealth centersG antibodiesLassa feverLassa virusDifferent occupational groupsPrevalenceAntibodiesOccupational groupsFeverSeroprevalenceIgMInfectionWorkersNursesAn indirect immunofluorescence assay using a cell culture-derived antigen for detection of antibodies to the agent of human granulocytic ehrlichiosis
Nicholson W, Comer J, Sumner J, Gingrich-Baker C, Coughlin R, Magnarelli L, Olson J, Childs J. An indirect immunofluorescence assay using a cell culture-derived antigen for detection of antibodies to the agent of human granulocytic ehrlichiosis. Journal Of Clinical Microbiology 1997, 35: 1510-1516. PMID: 9163471, PMCID: PMC229776, DOI: 10.1128/jcm.35.6.1510-1516.1997.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisCell culture-derived antigenHuman antibodiesGranulocytic ehrlichiosisIndirect immunofluorescenceHGE agentAnimal-derived antigensDetection of antibodiesTick-derived isolatesPromyelocytic leukemia cell lineAntigen presentationHuman promyelocytic leukemia cell lineHealthy individualsLeukemia cell linesHGE patientsSera reactiveEhrlichia phagocytophilaHigh titersAntigenImmunofluorescence methodE. equiEhrlichia equiRoutine testingAntibodiesSpecific antibodies
1995
Cluster of five children with acute encephalopathy associated with cat-scratch disease in South Florida
NOAH D, BRESEE J, GORENSEK M, ROONEY J, CRESANTA J, REGNERY R, WONG J, DEL TORO J, OLSON J, CHILDS J. Cluster of five children with acute encephalopathy associated with cat-scratch disease in South Florida. The Pediatric Infectious Disease Journal 1995, 14: 866-869. PMID: 8584313, DOI: 10.1097/00006454-199510000-00009.Peer-Reviewed Original ResearchConceptsCat-scratch diseaseAcute encephalopathyEvaluation of childrenIndirect fluorescent antibodyRegional lymphadenopathyStatus epilepticusSingle hospitalEncephalopathy casesBartonella henselaeEncephalopathyB. henselaeFocal clustersCausative agentFluorescent antibodyStray catsDiseaseChildrenAntibodiesHenselaeHigher proportionCatsLymphadenopathyEpilepticusEncephalitisPatients
1994
Susceptibility of white-tailed deer (Odocoileus virginianus) to infection with Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis
Dawson J, Stallknecht D, Howerth E, Warner C, Biggie K, Davidson W, Lockhart J, Nettles V, Olson J, Childs J. Susceptibility of white-tailed deer (Odocoileus virginianus) to infection with Ehrlichia chaffeensis, the etiologic agent of human ehrlichiosis. Journal Of Clinical Microbiology 1994, 32: 2725-2728. PMID: 7852563, PMCID: PMC264150, DOI: 10.1128/jcm.32.11.2725-2728.1994.Peer-Reviewed Original ResearchConceptsHuman ehrlichiosisE. canisE. chaffeensisEtiologic agentAbsence of seroconversionEhrlichia chaffeensisMacrophage-type cellsE. chaffeensis infectionLymph nodesPeripheral bloodClinical diseaseDay 10InfectionEhrlichia canisEhrlichiosisAntibodiesWhite-tailed deerChaffeensisNegative controlCanisReservoir hostsCompetent reservoirsWeeksTick vectorSeroconversion
1993
Antibodies to Borrelia burgdorferi and tick salivary gland proteins in New Jersey outdoor workers.
Schwartz B, Goldstein M, Childs J. Antibodies to Borrelia burgdorferi and tick salivary gland proteins in New Jersey outdoor workers. American Journal Of Public Health 1993, 83: 1746-8. PMID: 8259808, PMCID: PMC1694949, DOI: 10.2105/ajph.83.12.1746.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsAntibodiesAntibodies, BacterialArachnid VectorsBorrelia burgdorferi GroupCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayFemaleFollow-Up StudiesHumansLyme DiseaseMaleNew JerseyOccupational DiseasesPrevalenceRisk FactorsSalivary Proteins and PeptidesSeroepidemiologic StudiesSurveys and QuestionnairesTicksWorkplaceConceptsOutdoor workersBorrelia burgdorferiCross-sectional studyB. burgdorferi infectionSecond cross-sectional studyEnzyme-linked immunosorbentLyme disease seroprevalenceAntibody seropositivitySalivary gland proteinsBurgdorferi infectionTick exposureHigh riskLyme diseaseDisease seroprevalenceAntibodiesBurgdorferiGland proteinsSeropositivitySeroprevalenceInfectionPrevalenceDiseaseImmunosorbentWorkersEntomologic and demographic correlates of anti-tick saliva antibody in a prospective study of tick bite subjects in Westchester County, New York.
Schwartz B, Nadelman R, Fish D, Childs J, Forseter G, Wormser G. Entomologic and demographic correlates of anti-tick saliva antibody in a prospective study of tick bite subjects in Westchester County, New York. American Journal Of Tropical Medicine And Hygiene 1993, 48: 50-7. PMID: 8427388, DOI: 10.4269/ajtmh.1993.48.50.Peer-Reviewed Original ResearchConceptsSaliva antibodiesIndependent predictorsI. damminiLate-stage Lyme diseaseStrong independent predictorEnzyme-linked immunosorbentEngorgement indicesErythema migransProspective studyAntibody responseBiologic markersRisk factorsTick biteTick exposureNormal controlsSubject ageLogistic regressionLyme diseaseSalivary glandsOptical density valuesBiteTick engorgementConsistent changesDemographic correlatesAntibodies
1992
Lymphocytic choriomeningitis virus infection and house mouse (Mus musculus) distribution in urban Baltimore.
Childs J, Glass G, Korch G, Ksiazek T, Leduc J. Lymphocytic choriomeningitis virus infection and house mouse (Mus musculus) distribution in urban Baltimore. American Journal Of Tropical Medicine And Hygiene 1992, 47: 27-34. PMID: 1636880, DOI: 10.4269/ajtmh.1992.47.27.Peer-Reviewed Original ResearchRisk factors associated with antibodies to leptospires in inner-city residents of Baltimore: a protective role for cats.
Childs J, Schwartz B, Ksiazek T, Graham R, LeDuc J, Glass G. Risk factors associated with antibodies to leptospires in inner-city residents of Baltimore: a protective role for cats. American Journal Of Public Health 1992, 82: 597-599. PMID: 1546785, PMCID: PMC1694107, DOI: 10.2105/ajph.82.4.597.Peer-Reviewed Original Research
1991
Anti-tick Saliva Antibody: A Biologic Marker of Tick Exposure That Is a Risk Factor for Lime Disease Seropositivity
Schwartz B, Ford D, Childs J, Rothman N, Thomas R. Anti-tick Saliva Antibody: A Biologic Marker of Tick Exposure That Is a Risk Factor for Lime Disease Seropositivity. American Journal Of Epidemiology 1991, 134: 86-95. PMID: 1853864, DOI: 10.1093/oxfordjournals.aje.a115996.Peer-Reviewed Original ResearchHuman-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population.
Childs J, Glass G, Ksiazek T, Rossi C, Oro J, Leduc J. Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population. American Journal Of Tropical Medicine And Hygiene 1991, 44: 117-21. PMID: 1672798, DOI: 10.4269/ajtmh.1991.44.117.Peer-Reviewed Original ResearchConceptsLymphocytic choriomeningitis virusSeoul virusRodent-borne virusesHuman-rodent contactHistory of travelInner-city populationDisease clinicRodent exposureLymphocytic choriomeningitisAntibody prevalenceNeutralization testSerological testsAntibodiesVirusHigh rateInfectionRatsMore exposureExposureQuestionnaire responsesChoriomeningitisClinicPrevalenceMicePersons
1988
EVIDENCE OF HUMAN INFECTION WITH A RAT-ASSOCIATED HANTAVIRUS IN BALTIMORE, MARYLAND
CHILDS J, GLASS G, KORCH G, ARTHUR R, SHAH K, GLASSER D, ROSSI C, LEDUC J. EVIDENCE OF HUMAN INFECTION WITH A RAT-ASSOCIATED HANTAVIRUS IN BALTIMORE, MARYLAND. American Journal Of Epidemiology 1988, 127: 875-878. PMID: 3128102, DOI: 10.1093/oxfordjournals.aje.a114871.Peer-Reviewed Original Research
1987
EPIZOOTIOLOGY OF HANTAVIRUS INFECTIONS IN BALTIMORE: ISOLATION OF A VIRUS FROM NORWAY RATS, AND CHARACTERISTICS OF INFECTED RAT POPULATIONS
CHILDS J, KORCH G, GLASS G, LEDUC J, SHAH K. EPIZOOTIOLOGY OF HANTAVIRUS INFECTIONS IN BALTIMORE: ISOLATION OF A VIRUS FROM NORWAY RATS, AND CHARACTERISTICS OF INFECTED RAT POPULATIONS. American Journal Of Epidemiology 1987, 126: 55-68. PMID: 3109236, DOI: 10.1093/oxfordjournals.aje.a114662.Peer-Reviewed Original ResearchConceptsHantavirus infectionGeometric mean titersPrevalence of antibodiesAntibody prevalence ratesAntibody reactivity patternsMonoclonal antibody reactivity patternsAge-related mechanismsMean titersSerologic testsHigh prevalenceInfected ratsPrevalence ratesPresence of ratsRatsInfectionEnzootic natureUrban ratsSix-year periodHuman exposureRat massVirusPrevalenceAntibodiesHantavirusesUnited States
1986
Global survey of antibody to Hantaan-related viruses among peridomestic rodents.
LeDuc J, Smith G, Childs J, Pinheiro F, Maiztegui J, Niklasson B, Antoniades A, Robinson D, Khin M, Shortridge K. Global survey of antibody to Hantaan-related viruses among peridomestic rodents. Bulletin Of The World Health Organization 1986, 64: 139-44. PMID: 2425998, PMCID: PMC2490912.Peer-Reviewed Original ResearchConceptsHantaan-like virusNeutralization testHigher antibody prevalence ratesPlaque reduction neutralization testPrevalence of antibodiesReduction neutralization testAntibody prevalence ratesPrototype Hantaan virusHosts of hantavirusesSpecificity of antibodiesAntibody-positive rodentsPrevalence ratesRenal syndromeHaemorrhagic feverImmunofluorescent antibodyPositive seraHantaan virusPeridomestic rodentsSerological surveyRodent seraAntibodiesHantaanSerumCausative agentVirus
1985
Geographical distribution and age related prevalence of antibody to Hantaan-like virus in rat populations of Baltimore, Maryland, USA.
Childs J, Terry A, Leduc J, Korch G, Smith G. Geographical distribution and age related prevalence of antibody to Hantaan-like virus in rat populations of Baltimore, Maryland, USA. American Journal Of Tropical Medicine And Hygiene 1985, 34: 385-7. PMID: 3885776, DOI: 10.4269/ajtmh.1985.34.385.Peer-Reviewed Original Research