2013
Mecamylamine for Treatment of People With Dual Diagnoses of Depression and Alcohol Dependence
Ralevski E, Jane J, O’Brien E, Edens E, Arnaout B, Kerfoot K, Keegan K, Weiner J, Russo M, Petrakis I. Mecamylamine for Treatment of People With Dual Diagnoses of Depression and Alcohol Dependence. Journal Of Dual Diagnosis 2013, 9: 301-310. DOI: 10.1080/15504263.2013.835163.Peer-Reviewed Original ResearchDepressive symptomsAlcohol dependenceDual diagnosisRates of smokingMain outcome variablesSymptoms of depressionTreatment of peopleTreatment trialsComorbid depressionMecamylamineSide effectsNonsmokersSmokingSymptomsOutcome variablesBest treatmentDrinking outcomesDepressionPlaceboSmokersFurther studiesSignificant differencesDiagnosisParticipantsTreatment
2008
Alcohol Detoxification and Relapse Prevention Using Valproic Acid Versus Gabapentin in Alcohol-dependent Patients
Trevisan L, Ralevski E, Keegan K, Oville A, Vuppalapati D, Gonzalez G, Limoncelli D, Petrakis I. Alcohol Detoxification and Relapse Prevention Using Valproic Acid Versus Gabapentin in Alcohol-dependent Patients. Addictive Disorders & Their Treatment 2008, 7: 119-128. DOI: 10.1097/adt.0b013e31812e6a3c.Peer-Reviewed Original ResearchAlcohol withdrawalDays of treatmentSleep disturbancesAlcohol detoxificationModerate withdrawalValproic acidAcute alcohol withdrawalPlacebo-controlled trialMild withdrawal symptomsDoses of benzodiazepinesPrevention of relapseAlcohol-dependent patientsSymptoms of depressionPhysiologic withdrawalPostwithdrawal periodSupportive treatmentAcute symptomsBenzodiazepine medicationWithdrawal symptomsAcute withdrawalPsychiatric symptomsMale veteransClinical importancePsychiatric distressRelapse prevention