2021
Characterization of Aerosol Generation During Various Intensities of Exercise
Sajgalik P, Garzona-Navas A, Csécs I, Askew J, Lopez-Jimenez F, Niven A, Johnson B, Allison T. Characterization of Aerosol Generation During Various Intensities of Exercise. CHEST Journal 2021, 160: 1377-1387. PMID: 33957100, PMCID: PMC8473677, DOI: 10.1016/j.chest.2021.04.041.Peer-Reviewed Original ResearchConceptsHeart rate reserveRate reservePredicted heart rate reserveExercise testSafety of exercise testingPeak respiratory exchange ratioIntensity of exercisePeak heart rateRespiratory exchange ratioStages of exerciseExercise intensityExercise activitiesMaximal ventilationExchange ratioExerciseAerosol-generating proceduresActivity recoveryStatistically significant increaseSafety recommendationsHealthy volunteersFace of COVID-19Heart rateSignificant increaseRecommendationsCOVID-19Mitigation of Aerosols Generated During Exercise Testing With a Portable High-Efficiency Particulate Air Filter With Fume Hood
Garzona-Navas A, Sajgalik P, Csécs I, Askew J, Lopez-Jimenez F, Niven A, Johnson B, Allison T. Mitigation of Aerosols Generated During Exercise Testing With a Portable High-Efficiency Particulate Air Filter With Fume Hood. CHEST Journal 2021, 160: 1388-1396. PMID: 33895130, PMCID: PMC8463654, DOI: 10.1016/j.chest.2021.04.023.Peer-Reviewed Original ResearchConceptsExercise testing laboratoryPortable HEPA filterExercise testPortable high-efficiency particulate airAerosol concentrationsClearance timeConcentration of aerosolsExercise experienceStationary cyclingRisk of COVID-19 transmissionExerciseActivity recoveryHealthy volunteersAerosolQuiet breathingAerosol mitigationParticle counterAerosol clearanceClearance experimentsCOVID-19 pandemicCOVID-19 transmissionParticle concentrationLarger particlesCOVID-19
2020
Association Between Left Ventricular Mechanical Deformation and Myocardial Fibrosis in Nonischemic Cardiomyopathy
Csecs I, Pashakhanloo F, Paskavitz A, Jang J, Al‐Otaibi T, Neisius U, Manning W, Nezafat R. Association Between Left Ventricular Mechanical Deformation and Myocardial Fibrosis in Nonischemic Cardiomyopathy. Journal Of The American Heart Association 2020, 9: e016797. PMID: 33006296, PMCID: PMC7792406, DOI: 10.1161/jaha.120.016797.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementSeptal late gadolinium enhancementLV ejection fractionNonischemic cardiomyopathyExtent of fibrosisCardiovascular magnetic resonanceEjection fractionImpaired global circumferential strainImpaired LV ejection fractionLate gadolinium enhancement groupsDepressed LV ejection fractionClinical cardiovascular magnetic resonanceLeft ventricular (LVLGE-negative groupCircumferential strainGlobal radial strainGlobal longitudinal strainRadial strainGlobal circumferential strainLV deformation parametersGlobal LV functionAdverse cardiovascular outcomesLGE-positiveNonischemic fibrosisFibrosis burdenHigh-intensity endurance training is associated with left atrial fibrosis
Peritz D, Catino A, Csecs I, Kaur G, Kheirkhahan M, Loveless B, Wasmund S, Kholmovski E, Morris A, Marrouche N. High-intensity endurance training is associated with left atrial fibrosis. American Heart Journal 2020, 226: 206-213. PMID: 32615358, DOI: 10.1016/j.ahj.2020.05.015.Peer-Reviewed Original ResearchConceptsEndurance athletesMaster athletesHigh-intensity endurance trainingTrained endurance athletesNon-athlete controlsHealthy control subjectsLeft atrial fibrosisScreening colonoscopyEndurance trainingAthletic cohortHealthcare complexityAtrial fibrosisAthletesStudy participantsControl subjectsGeneral populationEnduranceQuantify fibrotic changesLeft atrial volumeIncreased atrial fibrosisLeft ventricular functionParticipantsAtrial volumeGadolinium enhancementFibrosis scoreHow are ECG parameters related to cardiac magnetic resonance images? Electrocardiographic predictors of left ventricular hypertrophy and myocardial fibrosis in hypertrophic cardiomyopathy
Dohy Z, Vereckei A, Horvath V, Czimbalmos C, Szabo L, Toth A, Suhai F, Csecs I, Becker D, Merkely B, Vago H. How are ECG parameters related to cardiac magnetic resonance images? Electrocardiographic predictors of left ventricular hypertrophy and myocardial fibrosis in hypertrophic cardiomyopathy. Annals Of Noninvasive Electrocardiology 2020, 25: e12763. PMID: 32329134, PMCID: PMC7507346, DOI: 10.1111/anec.12763.Peer-Reviewed Original ResearchConceptsRomhilt-Estes scoreLeft ventricular hypertrophyCardiac magnetic resonance imagingFragmented QRSSokolow-Lyon indexHypertrophic cardiomyopathyMyocardial fibrosisCornell indexMagnetic resonance imagingVentricular hypertrophyRepolarization abnormalitiesPredictor of myocardial fibrosisElectrocardiographic parametersPresence of fragmented QRSLeft ventricular ejection fractionDetectable left ventricular hypertrophyElectrocardiographic voltage criteriaResonance imagingVentricular ejection fractionHypertrophic cardiomyopathy patientsStructural myocardial changesDegree of myocardial fibrosisPathologic Q wavesAmount of fibrosisEjection fractionLeft atrial fibrosis progression detected by LGE‐MRI after ablation of atrial fibrillation
Kheirkhahan M, Baher A, Goldooz M, Kholmovski E, Morris A, Csecs I, Chelu M, Wilson B, Marrouche N. Left atrial fibrosis progression detected by LGE‐MRI after ablation of atrial fibrillation. Pacing And Clinical Electrophysiology 2020, 43: 402-411. PMID: 31867751, DOI: 10.1111/pace.13866.Peer-Reviewed Original ResearchConceptsAF recurrenceAF ablationLGE-MRIAtrial fibrillationLong-term procedural outcomesGadolinium-enhanced magnetic resonance imagingAssociated with significantly higher riskArrhythmia-free survivalAtrial arrhythmia recurrencePostablation AF recurrenceLate gadolinium enhancement magnetic resonance imagingEnhanced magnetic resonance imagingFollow-up periodSignificantly higher riskCardiovascular risk factorsMagnetic resonance imagingMonths postablationArrhythmia recurrenceConsecutive patientsLA fibrosisAblation proceduresFibrosis progressionProcedural outcomesAblation lesionsRecurrence
2019
Left atrial functional and structural changes associated with ablation of atrial fibrillation - Cardiac magnetic resonance study
Csécs I, Yamaguchi T, Kheirkhahan M, Czimbalmos C, Fochler F, Kholmovski E, Morris A, Kaur G, Vago H, Merkely B, Chelu M, Marrouche N, Wilson B. Left atrial functional and structural changes associated with ablation of atrial fibrillation - Cardiac magnetic resonance study. International Journal Of Cardiology 2019, 305: 154-160. PMID: 31874788, DOI: 10.1016/j.ijcard.2019.12.010.Peer-Reviewed Original ResearchConceptsCardiac magnetic resonance imagingCardiac magnetic resonance studyLA-LGEPredictors of recurrenceLate gadolinium enhancementLA volumeAtrial fibrillationPredictor of arrhythmia recurrenceSuccess of AF ablationAssessment of LA functionSelection of optimal treatment strategiesSuccess of atrial fibrillationOptimal treatment strategyBaseline functional parametersAssociated with ablationMagnetic resonance imagingArrhythmia recurrenceAF ablationAF patientsAtrial functionLA functionPost-ablationUnivariate analysisTreatment strategiesRecurrenceThe effect of contrast agents on left ventricular parameters calculated by a threshold-based software module: does it truly matter?
Szűcs A, Kiss A, Suhai F, Tóth A, Gregor Z, Horváth M, Czimbalmos C, Csécs I, Dohy Z, Szabó L, Merkely B, Vágó H. The effect of contrast agents on left ventricular parameters calculated by a threshold-based software module: does it truly matter? The International Journal Of Cardiovascular Imaging 2019, 35: 1683-1689. PMID: 31037474, PMCID: PMC6700040, DOI: 10.1007/s10554-019-01587-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomechanical PhenomenaCase-Control StudiesContrast MediaFemaleHeart VentriclesHumansImage Interpretation, Computer-AssistedIsolated Noncompaction of the Ventricular MyocardiumMagnetic Resonance Imaging, CineMaleMeglumineMiddle AgedOrganometallic CompoundsPredictive Value of TestsProspective StudiesReproducibility of ResultsSoftwareStroke VolumeVentricular Function, LeftYoung AdultConceptsSteady-state free precessionGadobenate dimeglumineCine imagesLeft ventricular parametersAdministration of contrast agentContrast agentsLeft ventricular volumeBlood-myocardium contrastEffects of contrast agentsNoncompaction cardiomyopathyVentricular parametersTrabecular musclesVentricular volumeCardiac parametersPre-CASShort axisTime-saving techniqueGadobutrolTrabecular massH groupFree precessionTrabecularEffect of CALVmassCardiomyopathyThe demanding grey zone: Sport indices by cardiac magnetic resonance imaging differentiate hypertrophic cardiomyopathy from athlete’s heart
Czimbalmos C, Csecs I, Toth A, Kiss O, Suhai F, Sydo N, Dohy Z, Apor A, Merkely B, Vago H. The demanding grey zone: Sport indices by cardiac magnetic resonance imaging differentiate hypertrophic cardiomyopathy from athlete’s heart. PLOS ONE 2019, 14: e0211624. PMID: 30763323, PMCID: PMC6375568, DOI: 10.1371/journal.pone.0211624.Peer-Reviewed Original ResearchConceptsCardiac magnetic resonancePathological left ventricular hypertrophyHypertrophic cardiomyopathyVentricular hypertrophySport indexCardiac magnetic resonance imagingEnd-diastolic volume ratioHypertrophic cardiomyopathy patientsLeft ventricular massEnd-diastolic wall thicknessCut-off valueGray zoneMagnetic resonance imagingHCM patientsCardiomyopathy patientsTrained athletesVentricular massPhysiological hypertrophyDiagnostic accuracyAthlete's heartCardiomyopathyHypertrophyMale subgroupResonance imagingEDWT
2017
Fractional flow reserve guided stenting of a myocardial bridge
Bárczi G, Csécs I, Ruzsa Z, Merkely B. Fractional flow reserve guided stenting of a myocardial bridge. The Anatolian Journal Of Cardiology 2017, 17: 251-252. PMID: 28321102, PMCID: PMC5864992, DOI: 10.14744/anatoljcardiol.2017.7406.Peer-Reviewed Original Research