High-intensity endurance training is associated with left atrial fibrosis
Peritz D, Catino A, Csecs I, Kaur G, Kheirkhahan M, Loveless B, Wasmund S, Kholmovski E, Morris A, Marrouche N. High-intensity endurance training is associated with left atrial fibrosis. American Heart Journal 2020, 226: 206-213. PMID: 32615358, DOI: 10.1016/j.ahj.2020.05.015.Peer-Reviewed Original ResearchConceptsEndurance athletesMaster athletesHigh-intensity endurance trainingTrained endurance athletesNon-athlete controlsHealthy control subjectsLeft atrial fibrosisScreening colonoscopyEndurance trainingAthletic cohortHealthcare complexityAtrial fibrosisAthletesStudy participantsControl subjectsGeneral populationEnduranceQuantify fibrotic changesLeft atrial volumeIncreased atrial fibrosisLeft ventricular functionParticipantsAtrial volumeGadolinium enhancementFibrosis scoreLeft atrial fibrosis progression detected by LGE‐MRI after ablation of atrial fibrillation
Kheirkhahan M, Baher A, Goldooz M, Kholmovski E, Morris A, Csecs I, Chelu M, Wilson B, Marrouche N. Left atrial fibrosis progression detected by LGE‐MRI after ablation of atrial fibrillation. Pacing And Clinical Electrophysiology 2020, 43: 402-411. PMID: 31867751, DOI: 10.1111/pace.13866.Peer-Reviewed Original ResearchConceptsAF recurrenceAF ablationLGE-MRIAtrial fibrillationLong-term procedural outcomesGadolinium-enhanced magnetic resonance imagingAssociated with significantly higher riskArrhythmia-free survivalAtrial arrhythmia recurrencePostablation AF recurrenceLate gadolinium enhancement magnetic resonance imagingEnhanced magnetic resonance imagingFollow-up periodSignificantly higher riskCardiovascular risk factorsMagnetic resonance imagingMonths postablationArrhythmia recurrenceConsecutive patientsLA fibrosisAblation proceduresFibrosis progressionProcedural outcomesAblation lesionsRecurrence