2021
DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis
Laut C, Leasure C, Pi H, Carlin S, Chu M, Hillebrand G, Lin H, Yi X, Stauff D, Skaar E. DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis. Infection And Immunity 2021, 90: e00560-21. PMID: 34748369, PMCID: PMC8788696, DOI: 10.1128/iai.00560-21.Peer-Reviewed Original ResearchConceptsTwo-component systemGene expressionSubstrate-binding subunitSignal transduction activityTarget gene expressionB. anthracisBacillus anthracisGram-positive bacteriumHost-induced stressesClpXP proteaseProtein chaperonesSignal transductionClpXGene productsTransduction activityDnaJVertebrate hostsHeme levelsHomeostasis regulatorGenetic selectionHigh heme levelsCell envelope disruptionBioterror weaponHssRSAnthracis
2020
Dysregulation of Magnesium Transport Protects Bacillus subtilis against Manganese and Cobalt Intoxication
Pi H, Wendel B, Helmann J. Dysregulation of Magnesium Transport Protects Bacillus subtilis against Manganese and Cobalt Intoxication. Journal Of Bacteriology 2020, 202: 10.1128/jb.00711-19. PMID: 31964700, PMCID: PMC7167470, DOI: 10.1128/jb.00711-19.Peer-Reviewed Original Research
2010
Direct Measurements of the Outer Membrane Stage of Ferric Enterobactin Transport POSTUPTAKE BINDING*
Newton S, Trinh V, Pi H, Klebba P. Direct Measurements of the Outer Membrane Stage of Ferric Enterobactin Transport POSTUPTAKE BINDING*. Journal Of Biological Chemistry 2010, 285: 17488-17497. PMID: 20335169, PMCID: PMC2878513, DOI: 10.1074/jbc.m109.100206.Peer-Reviewed Original Research
2002
Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development
Zhou L, Zhu C, Luo K, Li Y, Pi H, Yuan W, Wang Y, Huang C, Liu M, Wu X. Identification and characterization of two novel zinc finger genes, ZNF359 and ZFP28, in human development. Biochemical And Biophysical Research Communications 2002, 295: 862-868. PMID: 12127974, DOI: 10.1016/s0006-291x(02)00759-3.Peer-Reviewed Original ResearchConceptsZinc finger geneAmino acid proteinFinger geneKRAB domainTranscription factorsCDNA sequenceAcid proteinC2H2 zinc finger motifsNovel zinc finger geneN-terminal KRAB domainDevelopment-specific expression patternsN-terminal signal peptideHuman heart cDNA libraryZinc finger motifsHeart cDNA librarySingle largest classNorthern blot analysisC2H2 motifFinger motifRegulatory genesHuman genomeSignal peptideEmbryonic developmentCDNA libraryCardiac development