2000
Ouabain-sensitive H,K-ATPase Functions as Na,K-ATPase in Apical Membranes of Rat Distal Colon*
Rajendran V, Sangan P, Geibel J, Binder H. Ouabain-sensitive H,K-ATPase Functions as Na,K-ATPase in Apical Membranes of Rat Distal Colon*. Journal Of Biological Chemistry 2000, 275: 13035-13040. PMID: 10777607, DOI: 10.1074/jbc.275.17.13035.Peer-Reviewed Original Research
1998
Role of Apical H-K Exchange and Basolateral K Channel in the Regulation of Intracellular pH in Rat Distal Colon Crypt Cells
Ikuma M, Binder H, Geibel J. Role of Apical H-K Exchange and Basolateral K Channel in the Regulation of Intracellular pH in Rat Distal Colon Crypt Cells. The Journal Of Membrane Biology 1998, 166: 205-212. PMID: 9843594, DOI: 10.1007/s002329900462.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntiportersBariumCell PolarityColonEpithelial CellsH(+)-K(+)-Exchanging ATPaseHomeostasisHydrogen-Ion ConcentrationIntestinal MucosaIntracellular FluidIon TransportMaleOuabainPotassiumPotassium ChannelsPotassium-Hydrogen AntiportersRatsRats, Sprague-DawleySodium-Potassium-Exchanging ATPase
1995
Functional expression and segmental localization of rat colonic K-adenosine triphosphatase.
Lee J, Rajendran V, Mann A, Kashgarian M, Binder H. Functional expression and segmental localization of rat colonic K-adenosine triphosphatase. Journal Of Clinical Investigation 1995, 96: 2002-2008. PMID: 7560093, PMCID: PMC185838, DOI: 10.1172/jci118247.Peer-Reviewed Original ResearchAdenosine TriphosphatasesAnimalsBase SequenceCation Transport ProteinsColonDNA, ComplementaryMolecular Sequence DataOuabainRabbitsRatsSodium-Potassium-Exchanging ATPase
1991
Apical membrane localization of ouabain-sensitive K(+)-activated ATPase activities in rat distal colon
Del Castillo J, Rajendran V, Binder H. Apical membrane localization of ouabain-sensitive K(+)-activated ATPase activities in rat distal colon. American Journal Of Physiology 1991, 261: g1005-g1011. PMID: 1837421, DOI: 10.1152/ajpgi.1991.261.6.g1005.Peer-Reviewed Original ResearchConceptsRat distal colonOuabain-insensitive fractionDistal colonOuabain-sensitive fractionOuabain-insensitive componentHalf-maximal concentrationApical membraneATPase activityColonic mucosaProximal colonColonActivation curveAbsorptive processesAdenosinetriphosphatase activityApical membrane localizationBasolateral membraneHomogenatesN-ethylmaleimideMucosaActivityOmeprazole
1988
Electrolyte transport in distal colon of sodium-depleted rats: effect of sodium repletion
Turnamian S, Binder H. Electrolyte transport in distal colon of sodium-depleted rats: effect of sodium repletion. American Journal Of Physiology 1988, 255: g329-g338. PMID: 2844099, DOI: 10.1152/ajpgi.1988.255.3.g329.Peer-Reviewed Original ResearchMeSH KeywordsAldosteroneAmilorideAnimalsChloridesColonDiet, Sodium-RestrictedElectrolytesIn Vitro TechniquesIntestinal AbsorptionKineticsMaleRatsRats, Inbred StrainsReference ValuesSodiumSodium-Potassium-Exchanging ATPaseConceptsElectrogenic sodium absorptionElectroneutral sodium chloride absorptionPlasma aldosterone levelsAldosterone levelsSodium chloride absorptionPotassium secretionSodium absorptionSodium repletionDistal colonChloride absorptionElevated plasma aldosterone levelsSodium depletion increasesDistal colonic mucosaSodium-depleted ratsElectroneutral sodium absorptionRat distal colonExcess aldosteroneVoltage-clamp conditionsDietary sodiumColonic mucosaNormal animalsUnidirectional 22NaATPase activityElectrolyte transportSecretion
1986
Sodium and chloride transport in the large intestine of potassium-loaded rats
Budinger M, Foster E, Hayslett J, Binder H. Sodium and chloride transport in the large intestine of potassium-loaded rats. American Journal Of Physiology 1986, 251: g249-g252. PMID: 2426972, DOI: 10.1152/ajpgi.1986.251.2.g249.Peer-Reviewed Original ResearchMeSH KeywordsAdaptation, PhysiologicalAldosteroneAmilorideAnimalsBiological Transport, ActiveChloridesColonIon ChannelsMalePotassiumRatsRats, Inbred StrainsSodiumSodium-Potassium-Exchanging ATPaseConceptsPotassium secretionSodium absorptionRat distal colonic mucosaElectroneutral sodium chloride absorptionPotassium loadingNa-K-ATPase activityElectrogenic sodium absorptionDistal colonic mucosaActive potassium secretionPotassium-loaded ratsNet sodium absorptionSodium chloride absorptionActive sodium transportVoltage-clamp conditionsDietary potassiumColonic functionColonic mucosaNet chloride fluxNet sodium fluxJNanetNet sodiumLarge intestineChloride fluxSodium transportIdentical increase
1984
The Pathophysiology of Diarrhea
Binder H. The Pathophysiology of Diarrhea. Hospital Practice 1984, 19: 107-118. PMID: 6148347, DOI: 10.1080/21548331.1984.11702924.Peer-Reviewed Original ResearchColonic potassium transport.
Foster E, Hayslett J, Binder H. Colonic potassium transport. Kroc Foundation Series 1984, 17: 47-63. PMID: 6096514.Peer-Reviewed Original ResearchAnimalsBiological TransportChloridesColonCyclic AMPHumansMembrane PotentialsPotassiumSodium-Potassium-Exchanging ATPaseVasoactive Intestinal Peptide
1980
Amplification of cell membrane surface in potassium adaptation.
Kashgarian M, Taylor C, Binder H, Hayslett J. Amplification of cell membrane surface in potassium adaptation. Laboratory Investigation 1980, 42: 581-8. PMID: 6248685.Peer-Reviewed Original ResearchAnimalsCell MembraneColonDiet, Sodium-RestrictedGlucocorticoidsMicroscopy, ElectronMucous MembranePotassiumRatsSodiumSodium-Potassium-Exchanging ATPase