1988
Electrolyte transport in distal colon of sodium-depleted rats: effect of sodium repletion
Turnamian S, Binder H. Electrolyte transport in distal colon of sodium-depleted rats: effect of sodium repletion. American Journal Of Physiology 1988, 255: g329-g338. PMID: 2844099, DOI: 10.1152/ajpgi.1988.255.3.g329.Peer-Reviewed Original ResearchConceptsElectrogenic sodium absorptionElectroneutral sodium chloride absorptionPlasma aldosterone levelsAldosterone levelsSodium chloride absorptionPotassium secretionSodium absorptionSodium repletionDistal colonChloride absorptionElevated plasma aldosterone levelsSodium depletion increasesDistal colonic mucosaSodium-depleted ratsElectroneutral sodium absorptionRat distal colonExcess aldosteroneVoltage-clamp conditionsDietary sodiumColonic mucosaNormal animalsUnidirectional 22NaATPase activityElectrolyte transportSecretion
1986
Role of Aldosterone in the Regulation of Sodium and Chloride Transport in the Distal Colon of Sodium-Depleted Rats
Halevy J, Budinger M, Hayslett J, Binder H. Role of Aldosterone in the Regulation of Sodium and Chloride Transport in the Distal Colon of Sodium-Depleted Rats. Gastroenterology 1986, 91: 1227-1233. PMID: 3758615, DOI: 10.1016/s0016-5085(86)80021-x.Peer-Reviewed Original ResearchConceptsElectroneutral sodium chloride absorptionElectrogenic sodium absorptionSodium chloride absorptionRole of aldosteroneSodium-depleted animalsSodium absorptionChloride absorptionAldosterone infusionDistal colonPotassium secretionAmiloride-sensitive sodium absorptionContinuous aldosterone infusionDietary sodium depletionDistal colonic mucosaElevated aldosterone levelsActive potassium secretionRat distal colonAddition of amilorideRegulation of sodiumVoltage-clamp conditionsAldosterone levelsTime-dependent mannerSodium depletionColonic mucosaAldosterone
1985
Role of Aldosterone and Dietary Potassium in Potassium Adaptation in the Distal Colon of the Rat
Foster E, Jones W, Hayslett J, Binder H. Role of Aldosterone and Dietary Potassium in Potassium Adaptation in the Distal Colon of the Rat. Gastroenterology 1985, 88: 41-46. PMID: 3964771, DOI: 10.1016/s0016-5085(85)80130-x.Peer-Reviewed Original ResearchConceptsPotassium-enriched dietChronic potassium loadingNet potassium secretionAldosterone levelsDietary potassiumPotassium adaptationNet potassium transportPotassium secretionAldosterone-independent mechanismsBasal aldosterone levelsPotassium-loaded animalsRole of aldosteronePotassium loadingInfusion of aldosteroneDistal colonic mucosaEffects of aldosteroneIntact adrenal glandsNet potassium absorptionPotassium transportAdrenal glandDistal colonColonic mucosaIntact ratsAdrenalectomized animalsExperimental rats