2022
A neuromarker for drug and food craving distinguishes drug users from non-users
Koban L, Wager T, Kober H. A neuromarker for drug and food craving distinguishes drug users from non-users. Nature Neuroscience 2022, 26: 316-325. PMID: 36536243, DOI: 10.1038/s41593-022-01228-w.Peer-Reviewed Original ResearchConceptsFood cravingsFunctional magnetic resonance imaging studySelf-regulation strategiesCue-induced drugMagnetic resonance imaging studySelf-reported intensityResonance imaging studyFood cuesVentromedial prefrontalSubstance use disordersIntrospective accessMaladaptive behaviorsNeurobiological markersNeurobiological mechanismsParietal association areasCingulate cortexVentral striatumConvergent validityCore featuresCravingAssociation areasSubstance useNeuromarkersUse disordersClinical interventionsA methodological checklist for fMRI drug cue reactivity studies: development and expert consensus
Ekhtiari H, Zare-Bidoky M, Sangchooli A, Janes AC, Kaufman MJ, Oliver JA, Prisciandaro JJ, Wüstenberg T, Anton RF, Bach P, Baldacchino A, Beck A, Bjork JM, Brewer J, Childress AR, Claus ED, Courtney KE, Ebrahimi M, Filbey FM, Ghahremani DG, Azbari PG, Goldstein RZ, Goudriaan AE, Grodin EN, Hamilton JP, Hanlon CA, Hassani-Abharian P, Heinz A, Joseph JE, Kiefer F, Zonoozi AK, Kober H, Kuplicki R, Li Q, London ED, McClernon J, Noori HR, Owens MM, Paulus MP, Perini I, Potenza M, Potvin S, Ray L, Schacht JP, Seo D, Sinha R, Smolka MN, Spanagel R, Steele VR, Stein EA, Steins-Loeber S, Tapert SF, Verdejo-Garcia A, Vollstädt-Klein S, Wetherill RR, Wilson SJ, Witkiewitz K, Yuan K, Zhang X, Zilverstand A. A methodological checklist for fMRI drug cue reactivity studies: development and expert consensus. Nature Protocols 2022, 17: 567-595. PMID: 35121856, PMCID: PMC9063851, DOI: 10.1038/s41596-021-00649-4.Peer-Reviewed Original ResearchMeSH KeywordsChecklistCuesDelphi TechniqueHumansMagnetic Resonance ImagingReproducibility of ResultsConceptsSubstance use disordersSystematic reviewReporting of itemsMagnetic resonance imaging studyDelphi consensus methodResonance imaging studyFunctional magnetic resonance imaging studyInitial checklistCue-reactivity studiesConsensus statementSUD treatmentConsensus paperUse disordersExpert consensusImaging studiesTask-based fMRICue reactivityIncomplete reportingMethodological checklistStructured recommendationsFMRI informationClinical translationChecklistFinal checklistReviewMeta-analysis of human prediction error for incentives, perception, cognition, and action
Corlett PR, Mollick JA, Kober H. Meta-analysis of human prediction error for incentives, perception, cognition, and action. Neuropsychopharmacology 2022, 47: 1339-1349. PMID: 35017672, PMCID: PMC9117315, DOI: 10.1038/s41386-021-01264-3.Peer-Reviewed Original ResearchMeSH KeywordsArtificial IntelligenceCognitionHumansMagnetic Resonance ImagingMotivationPerceptionRewardConceptsPE signalsDorsomedial prefrontal cortexFamily-wise error correctionPrediction errorHealthy adult participantsSocial inferenceVisual hierarchyVisual perceptionActivation coordinatesFunctional neuroimagingPrefrontal cortexCognitive functionComputational neuroscienceAdult participantsCognitionNeural firingPerceptionError signalArtificial intelligenceTheoretical modelSmall sample sizeWhole brainNeuroscienceRewardMKDA
2021
The self in context: brain systems linking mental and physical health
Koban L, Gianaros PJ, Kober H, Wager TD. The self in context: brain systems linking mental and physical health. Nature Reviews Neuroscience 2021, 22: 309-322. PMID: 33790441, PMCID: PMC8447265, DOI: 10.1038/s41583-021-00446-8.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingEgoHealth StatusHumansMagnetic Resonance ImagingMental HealthNerve NetPrefrontal CortexConceptsVentromedial prefrontal cortexDefault mode networkPhysical healthPrefrontal cortexHigh-level cognitionCause of experienceBrain systemsSomatic physiologySensory modalitiesNeural systemsPersonal meaningPeripheral physiologyMental healthFormation of narrativesConvergent alterationsSelfContext modelCortexImmune functionCognitionExperienceContextHealthBeliefsMindset
2019
Regulation of Craving and Negative Emotion in Alcohol Use Disorder
Suzuki S, Mell MM, O'Malley SS, Krystal JH, Anticevic A, Kober H. Regulation of Craving and Negative Emotion in Alcohol Use Disorder. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2019, 5: 239-250. PMID: 31892465, PMCID: PMC7010564, DOI: 10.1016/j.bpsc.2019.10.005.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DrinkingAlcoholismCravingEmotionsFemaleHumansMagnetic Resonance ImagingMaleConceptsAlcohol use disorderNegative emotionsNegative affectPrefrontal cortexIndividual differencesRegulation conditionsCognitive behavioral therapy treatmentEmotion regulation taskFunctional magnetic resonance imagingNegative affect conditionRegulation of cravingNegative alcohol expectanciesNotable individual differencesSelf-reported cravingBehavioral therapy treatmentUse disordersRegulation successCognitive strategiesAffect conditionRegulation strategiesAlcohol expectanciesPFC regionsNeural mechanismsRegulation taskAUD treatment
2016
Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral treatments
Kober H, Brewer JA, Height KL, Sinha R. Neural stress reactivity relates to smoking outcomes and differentiates between mindfulness and cognitive-behavioral treatments. NeuroImage 2016, 151: 4-13. PMID: 27693614, PMCID: PMC5373945, DOI: 10.1016/j.neuroimage.2016.09.042.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingCigarette SmokingCognitive Behavioral TherapyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMindfulnessSmoking CessationStress, PsychologicalTreatment OutcomeConceptsCognitive-behavioral treatmentFunctional magnetic resonance imagingStress reactivityMindfulness-based treatmentsAmerican Lung Association's FreedomUnderstanding of stressPsychological mechanismsMindfulness trainingNegative affectConjunction analysisMid insulaCBT groupStress provocationSmoking outcomesBrain regionsCessation treatmentEfficacy of MTCurrent studyEntire sampleDrug useSmoking cessationImportant implicationsMagnetic resonance imagingMindfulnessInsula
2010
Prefrontal–striatal pathway underlies cognitive regulation of craving
Kober H, Mende-Siedlecki P, Kross EF, Weber J, Mischel W, Hart CL, Ochsner KN. Prefrontal–striatal pathway underlies cognitive regulation of craving. Proceedings Of The National Academy Of Sciences Of The United States Of America 2010, 107: 14811-14816. PMID: 20679212, PMCID: PMC2930456, DOI: 10.1073/pnas.1007779107.Peer-Reviewed Original ResearchConceptsSubstance use disordersUse disordersPrefrontal cortexVentral tegmental areaSubstance-dependent populationsMore effective treatmentsLong-term consumptionDorsolateral prefrontal cortex activityPrefrontal cortex activityCigarette smokersTegmental areaVentrolateral prefrontal cortexVentral striatum activityVentral striatal activitySubgenual cingulateEffective treatmentLateral prefrontal cortexStriatal activityVentral striatumCortex activityFunctional imagingPhysical healthStriatum activityNeural activityCortex