2017
Joint estimation of activity image and attenuation sinogram using time-of-flight positron emission tomography data consistency condition filtering
Li Q, Li H, Kim K, Fakhri G. Joint estimation of activity image and attenuation sinogram using time-of-flight positron emission tomography data consistency condition filtering. Journal Of Medical Imaging 2017, 4: 023502-023502. PMID: 28466027, PMCID: PMC5405780, DOI: 10.1117/1.jmi.4.2.023502.Peer-Reviewed Original ResearchData consistency conditionsMaximum likelihood attenuation correction factorsAttenuation sinogramConsistency conditionsJoint estimationJoint log-likelihood functionPET emission dataAttenuation correction factorsTime-of-flight (TOFActive imagingJoint estimation methodLog-likelihood functionPoisson noiseReconstruction resultsAttenuation correctionSinogram filteringPrevent convergenceEmission dataSinogramPositron emission tomography dataEstimation methodComputer simulationsPositron emission tomographyIterative methodCorrection factor
2013
State of the Art in Cardiac Hybrid Technology: PET/MR
Nappi C, El Fakhri G. State of the Art in Cardiac Hybrid Technology: PET/MR. Current Cardiovascular Imaging Reports 2013, 6: 338-345. PMID: 24073295, PMCID: PMC3780420, DOI: 10.1007/s12410-013-9213-5.Peer-Reviewed Original ResearchMagnetic resonance imagingPositron emission tomographyAbsence of ionizing radiationPositron emission tomography systemLimitations of PET/MRISensitivity of positron emission tomographyRespiratory motionPhotomultiplier tubeClinical cardiac applicationsSoft tissue contrastPET-CTDetection chainPositron emission tomography dataCardiac morphologyCardiac PET/MRIClinical promisePET/MRIEmission tomographySimultaneous PET/MRIImaging modalitiesPET imagingResonance imagingClinical settingDynamic PET imagesTissue contrast
2011
Monitoring proton radiation therapy with in-room PET imaging
Zhu X, España S, Daartz J, Liebsch N, Ouyang J, Paganetti H, Bortfeld T, Fakhri G. Monitoring proton radiation therapy with in-room PET imaging. Physics In Medicine And Biology 2011, 56: 4041-4057. PMID: 21677366, PMCID: PMC3141290, DOI: 10.1088/0031-9155/56/13/019.Peer-Reviewed Original ResearchConceptsIn-room positron emission tomographyIn-roomProton therapy treatment roomPositron emission tomography systemProton range verificationSoft tissue-equivalent materialMonte Carlo predictionsTissue-equivalent materialsPositron emission tomography acquisition timesProton radiation therapyPositron emission tomographyBiological washoutRange verificationProton therapyList-modeActivity distribution patternsPhantom studyTreatment roomPET acquisitionSoft tissue regionsIn vivo verificationDeep-siteOff-line modalityPositron emission tomography dataAdenoid cystic carcinoma
2010
Novel Scatter Compensation of List-Mode PET Data Using Spatial and Energy Dependent Corrections
Guérin B, Fakhri G. Novel Scatter Compensation of List-Mode PET Data Using Spatial and Energy Dependent Corrections. IEEE Transactions On Medical Imaging 2010, 30: 759-773. PMID: 21118770, PMCID: PMC3120772, DOI: 10.1109/tmi.2010.2095025.Peer-Reviewed Original ResearchConceptsScattered coincidencesEnergy resolutionE-pdfNCAT phantomDependent correctionsEnergy of individual photonsScatter correctionEnergy dependent correctionsEnergy probability density functionScatter correction schemeTotal energy spectrumList-mode acquisitionEnergy informationPositron emission tomography dataActivity distribution estimationScatter sinogramIndividual photonsEnergy spectrumCylindrical phantomEnergy distributionMonte Carlo simulationsScattering approachPhotonsScatteringScattering component
2009
SU‐FF‐J‐129: In‐Room Proton Range Verification Using Mobile NeuroPET ‐ Feasibility Study
Knopf A, Zhu X, Parodi K, Paganetti H, Bortfeld T, Fakhri G. SU‐FF‐J‐129: In‐Room Proton Range Verification Using Mobile NeuroPET ‐ Feasibility Study. Medical Physics 2009, 36: 2506-2506. DOI: 10.1118/1.3181421.Peer-Reviewed Original ResearchProton range verificationRange verificationPET/CT scannerCommercial PET/CT scannersWater equivalent rangePositron emission tomographyBiological washoutPMMA phantomProton fieldsProton beamActivity depth profilesProton treatmentPhantom studyTreatment roomIn-roomPositron emission tomography scanPositron emission tomography dataPatient repositioningPhantomPositron emission tomography imagingProtonDepth profilesPET/CT imagingRadiation treatmentTotal dose