2018
Super-Resolution PET Using A Very Deep Convolutional Neural Network
Song T, Chowdhury S, Kim K, Gong K, Fakhri G, Li Q, Dutta J. Super-Resolution PET Using A Very Deep Convolutional Neural Network. 2018, 00: 1-2. DOI: 10.1109/nssmic.2018.8824683.Peer-Reviewed Original ResearchConvolutional neural networkNeural networkSuper-resolution convolutional neural networkDeep convolutional neural networkImage deblurring approachesInput image patchesBlur kernelResolution recovery techniquesSpatial location informationDeblurring approachDeblurring processImage patchesQuantitative accuracy of PETLocation informationSpatially-varying natureSuperior performanceNetworkRecovery techniquesDigital phantomDeblurringBrainWebInformationPartial volume effectsDeepBlur
2017
Partial volume correction for PET quantification and its impact on brain network in Alzheimer’s disease
Yang J, Hu C, Guo N, Dutta J, Vaina L, Johnson K, Sepulcre J, Fakhri G, Li Q. Partial volume correction for PET quantification and its impact on brain network in Alzheimer’s disease. Scientific Reports 2017, 7: 13035. PMID: 29026139, PMCID: PMC5638902, DOI: 10.1038/s41598-017-13339-7.Peer-Reviewed Original ResearchConceptsQuantitative accuracy of PET imagesSpatial resolution of PET scannersAccuracy of PET imagesPET scannerBrain networksPET imagingQuantitative accuracyPartial volume effectsClassification performanceImage registrationPositron emission tomography quantificationPartial volume correctionSpatial resolutionJoint entropyVolume correctionNetwork structure analysisCorrected imagesVolume effectClinical datasetsParameter settingsPositron emission tomographyClassification testsCompare network propertiesNoise sensitivity
2016
Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR
Petibon Y, Guehl N, Reese T, Ebrahimi B, Normandin M, Shoup T, Alpert N, Fakhri G, Ouyang J. Impact of motion and partial volume effects correction on PET myocardial perfusion imaging using simultaneous PET-MR. Physics In Medicine And Biology 2016, 62: 326-343. PMID: 27997375, PMCID: PMC5241952, DOI: 10.1088/1361-6560/aa5087.Peer-Reviewed Original ResearchConceptsSimultaneous PET-MRPET myocardial perfusion imagingMyocardial perfusion imagingPoint spread functionPoint-spread function correctionUngated dataMotion correctionPET-MRPartial volume effectsApparent wall thicknessMyocardial blood flowPartial volume effect correctionMR-based motion correctionMotion fieldPET-MR scannersPoint spread function modelPET dataPerfusion imagingImage qualityImpact of motionDynamic myocardial perfusion imagingAttenuation mapNon-rigid registrationAbsolute myocardial blood flowUngated images
2015
PET Point Spread Function Modeling and Image Deblurring Using a PET/MRI Joint Entropy Prior
Dutta J, Fakhri G, Zhu X, Li Q. PET Point Spread Function Modeling and Image Deblurring Using a PET/MRI Joint Entropy Prior. 2015, 1423-1426. DOI: 10.1109/isbi.2015.7164143.Peer-Reviewed Original ResearchJoint entropyDe-blurring techniqueImage deblurringBrain WebQuantitative accuracy of PETImage spaceEfficient frameworkDeconvolution problemDeblurringCost functionPoint spread function modelPenalty functionHuman datasetsSpatial resolution capabilitiesPET scannerAmplifier noisePET imagingImagesConsistent with MRIQuantitative accuracyPartial volume effectsPhantomDatasetEntropyFunction model
2013
Cardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study
Petibon Y, Ouyang J, Zhu X, Huang C, Reese T, Chun S, Li Q, Fakhri G. Cardiac motion compensation and resolution modeling in simultaneous PET-MR: a cardiac lesion detection study. Physics In Medicine And Biology 2013, 58: 2085-2102. PMID: 23470288, PMCID: PMC3657754, DOI: 10.1088/0031-9155/58/7/2085.Peer-Reviewed Original ResearchConceptsContrast recoveryDetector point spread functionPartial volume effectsK-spaceMotion compensationB-spline registrationLesion-detection studiesCardiac motion compensationPET-MR scannersSimultaneous PET-MRPET contrastIterative reconstruction frameworkPoint spread functionMotion correctionPET countsNon-rigid B-spline registrationCardiac phantomPSF modelPET-MRMotion deblurringReconstruction frameworkSystem matrixCardiac PETSpread functionDefect detection
2001
Absolute Activity Quantitation From Projections Using an Analytical Approach: Comparison With Iterative Methods in Tc-99M and I-123 Brain SPECT
Fakhri G, Kijewski M, Moore S. Absolute Activity Quantitation From Projections Using an Analytical Approach: Comparison With Iterative Methods in Tc-99M and I-123 Brain SPECT. IEEE Transactions On Nuclear Science 2001, 48: 768. DOI: 10.1109/23.940161.Peer-Reviewed Original ResearchVariable collimator responseI-123 studiesOrdered subsets-expectation maximizationI-123Tc-99mTc-99Brain phantomAttenuation correctionAnthropomorphic brain phantomDigital brain phantomTc-99m studiesMonte Carlo simulated projectionsCollimator responseActivity quantitationPathological patientsBrain structuresBrain SPECTActivity distributionPoor spatial resolutionSPECT activityQuantitative accuracyFitting procedurePartial volume effectsCaudate nucleusCorpus callosumAbsolute activity quantitation in simultaneous 123I/99mTc brain SPECT.
El Fakhri G, Moore S, Maksud P, Aurengo A, Kijewski M. Absolute activity quantitation in simultaneous 123I/99mTc brain SPECT. Journal Of Nuclear Medicine 2001, 42: 300-8. PMID: 11216530.Peer-Reviewed Original ResearchMeSH KeywordsAlzheimer DiseaseBenzamidesBrainCerebellumCerebral CortexCerebrovascular CirculationCorpus CallosumHumansIodine RadioisotopesMonte Carlo MethodNeural Networks, ComputerParkinson DiseasePhantoms, ImagingPutamenPyrrolidinesRadiopharmaceuticalsSensitivity and SpecificityTechnetium Tc 99m ExametazimeTomography, Emission-Computed, Single-PhotonConceptsOrdered-subset expectation maximizationDistance-dependent collimator responseActivity quantitationActivity distributionIterative ordered-subsets expectation maximizationZubal brain phantomAsymmetric windowsSimulated normal populationPathological studiesDecay photonsBrain SPECTCollimator responseNonuniform attenuationDual-isotope imagingBrain phantomMonte Carlo simulationsCorpus callosumNormal populationPartial volume effectsCarlo simulationsCortical lobesAssessment of brain perfusionScatteringCross-talkBrain perfusion
2000
Absolute activity quantitation from projections using an analytical approach: comparison with iterative methods in brain SPECT
Fakhri G, Kijewski M, Moore S. Absolute activity quantitation from projections using an analytical approach: comparison with iterative methods in brain SPECT. 2011 IEEE Nuclear Science Symposium Conference Record 2000, 3: 18/7-1811 vol.3. DOI: 10.1109/nssmic.2000.949215.Peer-Reviewed Original ResearchVariable collimator responseI-123 studiesI-123Tc-99Attenuation correctionTc-99mBrain SPECTDigital brain phantomTc-99m studiesMonte Carlo simulated projectionsCollimator responseActivity quantitationActivity estimationBrain phantomOSEM algorithmBrain structuresActivity distributionAccurate quantitationPoor spatial resolutionSPECT activityFitting procedurePartial volume effectsCaudate nucleusCorpus callosumSpatial resolution