2023
Search of a genomic sequence database for potential novel blood group antigens: Investigation into why some amino acid substitutions are not immunogenic
Howe J, Stack G. Search of a genomic sequence database for potential novel blood group antigens: Investigation into why some amino acid substitutions are not immunogenic. Transfusion 2023, 63: 1399-1411. PMID: 37386886, DOI: 10.1111/trf.17459.Peer-Reviewed Original ResearchConceptsBlood group antigensGroup antigensB-cell epitopesGenomic sequence databasesLinear B-cell epitopesLow prevalenceSequence databasesAtypical chemokine receptor 1Chemokine receptor 1New blood group antigensExtracellular domainHuman genome sequence databaseMissense mutationsGenome sequence databaseEpitope prediction programsTransfusion practiceProtein structural analysisPoor immunogenicityAmino acid substitutionsReceptor 1Phenotype prevalenceAntigenStudy designBlood groupPrevalence
2009
Estimation of Combat-Related Blood Group Alloimmunization and Delayed Serologic Transfusion Reactions in U.S. Military Veterans
Tormey CA, Stack G. Estimation of Combat-Related Blood Group Alloimmunization and Delayed Serologic Transfusion Reactions in U.S. Military Veterans. Military Medicine 2009, 174: 503-507. PMID: 20731281, DOI: 10.7205/milmed-d-02-5808.Peer-Reviewed Original ResearchConceptsSerologic transfusion reactionsTransfusion reactionsVeterans Affairs Medical CenterAnamnestic immune responseMilitary veteran patientsBlood group alloantibodiesMilitary veteransPre-existing antibodiesU.S. military veteransAlloimmunization ratePrior alloimmunizationVeteran patientsTransfusion recordsVA careImmune responseMedical CenterAlloimmunizationAlloantibodiesVeteransAntibodiesHigh rateTransfusionPatientsPrevalenceCare
2008
Red blood cell alloantibody frequency, specificity, and properties in a population of male military veterans
Tormey CA, Fisk J, Stack G. Red blood cell alloantibody frequency, specificity, and properties in a population of male military veterans. Transfusion 2008, 48: 2069-2076. PMID: 18631165, DOI: 10.1111/j.1537-2995.2008.01815.x.Peer-Reviewed Original ResearchConceptsRBC alloantibodiesMale military veteransDecade of birthMilitary veteransVA careRed blood cell alloantibodiesVeterans Affairs Medical CenterHospital-based patientsPercent of casesLarge male predominanceRace/ethnicityAlloantibody frequenciesAlloantibody specificitiesFrequent alloantibodiesTransfusion historyMale predominanceD alloimmunizationTransfusion recordsHigh prevalenceMedical CenterAlloantibodiesAntibody developmentAlloimmunizationAntiglobulin phasePrevalence