2013
A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms
Geisbüsch S, Stefanovic A, Schray D, Oyfe I, Lin HM, Di Luozzo G, Griepp RB. A prospective study of growth and rupture risk of small-to-moderate size ascending aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 68-74. PMID: 23953716, DOI: 10.1016/j.jtcvs.2013.06.030.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnticoagulantsAortaAortic AneurysmAortic RuptureAortographyCase-Control StudiesChi-Square DistributionDisease ProgressionFemaleFibrinolytic AgentsHumansLeast-Squares AnalysisLinear ModelsMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsTime FactorsTomography, X-Ray ComputedVascular Surgical ProceduresConceptsTotal aortic volumeAscending Aortic AneurysmAortic aneurysmAortic volumeModerate size aneurysmsReference groupML/yearAntithrombotic medicationAortic pathologySurgical indicationsUnderwent operationAortic sizeProspective studyEmergency departmentAortic growthSurveillance groupLarge aneurysmsRisk factorsSinotubular junctionTomography scanTomography volume measurementsDissection riskPatientsCompelling indicationsAneurysmsPredicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables
Shirali AS, Bischoff MS, Lin HM, Oyfe I, Lookstein R, Griepp RB, Di Luozzo G. Predicting the Risk for Acute Type B Aortic Dissection in Hypertensive Patients Using Anatomic Variables. JACC Cardiovascular Imaging 2013, 6: 349-357. PMID: 23433926, DOI: 10.1016/j.jcmg.2012.07.018.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdultAgedAntihypertensive AgentsAorta, ThoracicAortic AneurysmAortic DissectionAortographyBlood PressureChi-Square DistributionFemaleHumansHypertensionLinear ModelsLogistic ModelsMaleMiddle AgedMultidetector Computed TomographyMultivariate AnalysisPredictive Value of TestsPrognosisReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsROC CurveConceptsAcute type B aortic dissectionType B aortic dissectionHypertensive patientsB aortic dissectionAAD developmentAortic dissectionAortic archRisk factorsAortic tortuosityAggressive medical managementPre-emptive surgeryOnly risk factorProximal ascending aortaSignificant risk factorsAortic arch diameterStepwise logistic regressionNormotensive patientsAnatomic predictorsEntire aortaMedical managementArtery originAscending aortaTomography angiographyAortic rootAortic imaging
2012
Quality of life and survival of septuagenarians and octogenarians after repair of descending and thoracoabdominal aortic aneurysms
Di Luozzo G, Shirali AS, Varghese R, Lin HM, Weiss AJ, Bischoff MS, Griepp RB. Quality of life and survival of septuagenarians and octogenarians after repair of descending and thoracoabdominal aortic aneurysms. Journal Of Thoracic And Cardiovascular Surgery 2012, 145: 378-384. PMID: 22365063, DOI: 10.1016/j.jtcvs.2012.01.068.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overAortic Aneurysm, ThoracicFemaleHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleOdds RatioProportional Hazards ModelsQuality of LifeRespiratory Distress SyndromeRetrospective StudiesRisk AssessmentRisk FactorsSex FactorsSurveys and QuestionnairesTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsQuality of lifeBody mass indexGender-matched populationLong-term survivalHospital mortalityMass indexThoracoabdominal aortic aneurysm repairAcute respiratory distress syndromeHigher body mass indexComplex aortic operationsOne-year survivalThoracoabdominal aortic aneurysmsAortic aneurysm repairItem Health SurveyRespiratory distress syndromeLower vitality scoresTAAA repairAortic operationsElderly patientsAneurysm repairDistress syndromePostoperative qualityRetrospective reviewThoracic aneurysmLife scoresSelective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome
Uysal S, Lin HM, Fischer GW, Di Luozzo G, Reich DL. Selective cerebral perfusion for thoracic aortic surgery: Association with neurocognitive outcome. Journal Of Thoracic And Cardiovascular Surgery 2012, 143: 1205-1212. PMID: 22306226, DOI: 10.1016/j.jtcvs.2012.01.012.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAorta, ThoracicCardiopulmonary BypassCerebrovascular CirculationChi-Square DistributionCirculatory Arrest, Deep Hypothermia InducedCognitionCognition DisordersFemaleHumansLinear ModelsLogistic ModelsMaleMiddle AgedNeuropsychological TestsNew York CityPerfusionProspective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsSelective cerebral perfusionHypothermic circulatory arrestSelective cerebral perfusion timeCerebral perfusion timeCardiopulmonary bypass timeThoracic aortic surgeryCerebral perfusionCardiopulmonary bypassCirculatory arrestAortic surgeryBypass timeSurgical patientsNeurocognitive outcomesPerfusion timeHypothermic circulatory arrest timeAortic arch surgeryBrain protection strategiesGroup 3 patientsOptimal brain protectionPostoperative neurocognitive testingGroup 1 patientsGroup 2 patientsThoracic aortic repairCirculatory arrest timeNeurocognitive test scores
2010
The Bentall procedure: Is it the gold standard? A series of 597 consecutive cases
Etz CD, Bischoff MS, Bodian C, Roder F, Brenner R, Griepp RB, Di Luozzo G. The Bentall procedure: Is it the gold standard? A series of 597 consecutive cases. Journal Of Thoracic And Cardiovascular Surgery 2010, 140: s64-s70. PMID: 21092800, DOI: 10.1016/j.jtcvs.2010.07.033.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic AneurysmAortic ValveBioprosthesisBlood Vessel Prosthesis ImplantationChi-Square DistributionFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedNew York CityOdds RatioProsthesis DesignReoperationRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeYoung AdultConceptsAortic root reconstructionLong-term survivalBiological valvesMechanical valvesBentall procedureRoot reconstructionOverall hospital mortalityIndependent risk factorCoronary artery diseaseShort-term outcomesLong-term outcomesChoice of valveHospital mortalityPatients 50Artery diseaseDegenerative etiologyLinearized rateAortic valveConsecutive casesRisk factorsEmergency operationGold standardReoperationPatientsSurvivalPredicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair
Zoli S, Roder F, Etz CD, Brenner RM, Bodian CA, Lin HM, Di Luozzo G, Griepp RB. Predicting the Risk of Paraplegia After Thoracic and Thoracoabdominal Aneurysm Repair. The Annals Of Thoracic Surgery 2010, 90: 1237-1245. PMID: 20868820, DOI: 10.1016/j.athoracsur.2010.04.091.Peer-Reviewed Original ResearchConceptsSpinal cord injuryRisk of paraplegiaSegmental arteriesParaplegia riskEndovascular repairAneurysm repairCord injuryThoracoabdominal aortic aneurysm repairMotor-evoked potential monitoringPrevious aortic surgeryThoracoabdominal aneurysm repairIndependent risk factorThoracoabdominal aortic aneurysmsAortic aneurysm repairStandard surgical approachCerebrospinal fluid drainageCrawford classificationHospital mortalitySCI riskAortic surgeryEmergent operationSurgical approachAortic aneurysmRisk factorsAbdominal aortaNoninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery
Fischer GW, Lin HM, Krol M, Galati MF, Di Luozzo G, Griepp RB, Reich DL. Noninvasive cerebral oxygenation may predict outcome in patients undergoing aortic arch surgery. Journal Of Thoracic And Cardiovascular Surgery 2010, 141: 815-821. PMID: 20579669, DOI: 10.1016/j.jtcvs.2010.05.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAorta, ThoracicBlood Vessel Prosthesis ImplantationCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedCritical CareFemaleFrontal LobeHeart Arrest, InducedHospital CostsHumansLength of StayLogistic ModelsMaleMiddle AgedMonitoring, IntraoperativeNew York CityOximetryOxygenPostoperative ComplicationsPredictive Value of TestsRespiration, ArtificialRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeConceptsRegional oxygen saturationAortic arch surgeryArch surgeryOxygen saturationOrgan dysfunctionIntensive care unit lengthRegional oxygen saturation valuesTotal aortic arch replacementPostoperative organ dysfunctionAortic arch replacementExtended hospital staySevere adverse outcomesCerebral oxygenation valuesOxygen saturation valuesArch replacementHemiarch replacementExtubation timeHospital lengthHospital stayPostoperative complicationsCerebral oximetryMinor complicationsConsiderable morbidityMajor complicationsSurgical repairLong-Term Survival After Open Repair of Chronic Distal Aortic Dissection
Zoli S, Etz CD, Roder F, Mueller CS, Brenner RM, Bodian CA, Di Luozzo G, Griepp RB. Long-Term Survival After Open Repair of Chronic Distal Aortic Dissection. The Annals Of Thoracic Surgery 2010, 89: 1458-1466. PMID: 20417761, DOI: 10.1016/j.athoracsur.2010.02.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic Aneurysm, AbdominalAortic Aneurysm, ThoracicAortic DissectionBlood Vessel Prosthesis ImplantationCause of DeathChronic DiseaseCohort StudiesDatabases, FactualDisease-Free SurvivalFemaleFollow-Up StudiesHospital MortalityHumansMaleMiddle AgedMultivariate AnalysisPostoperative ComplicationsProbabilityRisk AssessmentSurvival AnalysisTime FactorsTreatment OutcomeVascular Surgical ProceduresConceptsChronic distal aortic dissectionDistal aortic dissectionAortic dissectionOpen repairAdverse outcomesAcute type ADistal aortic reoperationEndovascular stent-graft techniquesSegmental artery pairsStent-graft techniqueThrombosed false lumenCoronary artery diseaseLong-term survivalAortic reoperationChronic dissectionHospital mortalityB dissectionChronic dialysisAortic expansionVisceral arteriesArtery diseaseSurgical repairFalse lumenInitial diagnosisAortic diameterMathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest
Fischer GW, Benni PB, Lin H, Satyapriya A, Afonso A, Di Luozzo G, Griepp RB, Reich DL. Mathematical model for describing cerebral oxygen desaturation in patients undergoing deep hypothermic circulatory arrest. British Journal Of Anaesthesia 2010, 104: 59-66. PMID: 19933513, PMCID: PMC2791548, DOI: 10.1093/bja/aep335.Peer-Reviewed Original ResearchConceptsDeep hypothermic circulatory arrestHypothermic circulatory arrestCirculatory arrestCerebral desaturationArrest timeMin of DHCACerebral oxygen desaturationAortic arch diseaseArch diseaseAortic surgeryIschemic thresholdNeurological sequelaeOxygen desaturationCerebral oximetryCerebral ischaemiaSurgical treatmentPatient heightPatientsDesaturationArrestMixed modelsX logIschaemiaSequelaeSurgery
2009
Redo Lateral Thoracotomy for Reoperative Descending and Thoracoabdominal Aortic Repair: A Consecutive Series of 60 Patients
Etz CD, Zoli S, Kari FA, Mueller CS, Bodian CA, Di Luozzo G, Plestis KA, Griepp RB. Redo Lateral Thoracotomy for Reoperative Descending and Thoracoabdominal Aortic Repair: A Consecutive Series of 60 Patients. The Annals Of Thoracic Surgery 2009, 88: 758-767. PMID: 19699894, DOI: 10.1016/j.athoracsur.2009.04.140.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortic Aneurysm, ThoracicAortic CoarctationAortic DiseasesAortic DissectionAtherosclerosisCardiopulmonary BypassCirculatory Arrest, Deep Hypothermia InducedEvoked Potentials, MotorEvoked Potentials, SomatosensoryFemaleHeart Bypass, LeftHospital MortalityHumansKaplan-Meier EstimateMaleMarfan SyndromeMiddle AgedNeurologic ExaminationPostoperative ComplicationsReoperationSurvival RateThoracotomyYoung AdultConceptsPartial left heart bypassSegmental artery pairsHypothermic circulatory arrestLeft heart bypassPartial cardiopulmonary bypassPermanent dialysisAtherosclerotic aneurysmsCirculatory arrestCardiopulmonary bypassHeart bypassAdverse outcomesExtensive adhesionsThoracoabdominal aortic aneurysm surgeryArtery pairsChronic obstructive pulmonary diseaseAortic aneurysm surgeryIntensive care unit recoveryObstructive pulmonary diseaseThoracoabdominal aortic repairCoronary artery diseaseAneurysm extentHospital mortalityRedo thoracotomyTAAA repairRespiratory complicationsAortic Arch Resection and Ligation of the Descending Thoracic Aorta to Manage a Ruptured Thoracoabdominal Aneurysm
Weiss A, Di Luozzo G, Etz CD, Griepp RB. Aortic Arch Resection and Ligation of the Descending Thoracic Aorta to Manage a Ruptured Thoracoabdominal Aneurysm. Vascular And Endovascular Surgery 2009, 43: 614-616. PMID: 19640920, DOI: 10.1177/1538574409335273.Peer-Reviewed Original ResearchConceptsThoracoabdominal aortic aneurysmsAcute type B aortic dissectionType B aortic dissectionAortic arch resectionRuptured thoracoabdominal aneurysmHigh-risk patientsOpen surgical interventionOpen surgical repairB aortic dissectionThoracoabdominal aneurysmsAortic dissectionAortic ruptureEndovascular approachSurgical repairArch resectionSurgical interventionAortic aneurysmThoracic aortaPrimary operationPatientsAneurysmsLess conventional approachesRuptureReoperationResectionDirect Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair
Etz CD, Di Luozzo G, Zoli S, Lazala R, Plestis KA, Bodian CA, Griepp RB. Direct Spinal Cord Perfusion Pressure Monitoring in Extensive Distal Aortic Aneurysm Repair. The Annals Of Thoracic Surgery 2009, 87: 1764-1774. PMID: 19463592, DOI: 10.1016/j.athoracsur.2009.02.101.Peer-Reviewed Original ResearchConceptsSpinal cord perfusion pressureDeep hypothermic circulatory arrestThoracoabdominal aortic aneurysmsAortic aneurysm repairHypothermic circulatory arrestNonpulsatile cardiopulmonary bypassCardiopulmonary bypassPerfusion pressureSegmental arteriesEndovascular repairAneurysm repairCirculatory arrestAortic aneurysmThoracoabdominal aortic aneurysm repairNormal spinal cord functionPerfusion pressure monitoringThoracic segmental arteriesMean arterial pressureSpinal cord functionSpinal cord recoveryParaspinal collateral networkArterial pressureCord functionCollateral networkPressure monitoringSupradiaphragmatic Inferior Vena Cava Cannulation for Thoracoabdominal Aortic Aneurysm Repair
Di Luozzo G, Etz CD, Griepp RB. Supradiaphragmatic Inferior Vena Cava Cannulation for Thoracoabdominal Aortic Aneurysm Repair. The Annals Of Thoracic Surgery 2009, 87: 1286-1288. PMID: 19324177, DOI: 10.1016/j.athoracsur.2008.07.025.Peer-Reviewed Original ResearchConceptsSupradiaphragmatic inferior vena cavaThoracoabdominal aortic aneurysm repairDeep hypothermic circulatory arrestFemoral venous accessAortic aneurysm repairHypothermic circulatory arrestInferior vena cavaSite of cannulationThoracoabdominal aneurysmsCirculatory arrestAneurysm repairCardiopulmonary bypassCardiopulmonary supportVenous accessCannulation siteVena cavaPreoperative preparationCannulationRare occasions
2008
Reoperative aortic root and transverse arch procedures: A comparison with contemporaneous primary operations
Etz CD, Plestis KA, Homann TM, Bodian CA, Di Luozzo G, Spielvogel D, Griepp RB. Reoperative aortic root and transverse arch procedures: A comparison with contemporaneous primary operations. Journal Of Thoracic And Cardiovascular Surgery 2008, 136: 860-867.e3. PMID: 18954623, DOI: 10.1016/j.jtcvs.2007.11.071.Peer-Reviewed Original ResearchMeSH KeywordsAgedAortic Aneurysm, ThoracicAortic ValveBlood Vessel Prosthesis ImplantationCase-Control StudiesCause of DeathFollow-Up StudiesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHospital MortalityHumansIntraoperative ComplicationsKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisPostoperative ComplicationsReoperationRetrospective StudiesTreatment OutcomeConceptsArch proceduresAorta proceduresArch operationsPrimary procedureOperative mortalityRisk factorsPoor long-term outlookSex-matched normal populationChronic obstructive pulmonary diseaseAortic arch operationsHigher hospital mortalityHigh operative mortalityProximal aortic surgeryLongevity of patientsObstructive pulmonary diseaseSeparate multivariable analysesLong-term outcomesSignificant risk factorsLong-term outlookLong-term survivalContemporaneous patientsAortic surgeryHospital mortalityEjection fractionMultivariable analysisChromium Infusion Reverses Extreme Insulin Resistance in a Cardiothoracic ICU Patient
Via M, Scurlock C, Raikhelkar J, Di Luozzo G, Mechanick JI. Chromium Infusion Reverses Extreme Insulin Resistance in a Cardiothoracic ICU Patient. Nutrition In Clinical Practice 2008, 23: 325-328. PMID: 18595867, DOI: 10.1177/0884533608318676.Peer-Reviewed Original ResearchConceptsInsulin resistanceExtreme insulin resistanceInsulin therapyGlycemic controlIll patientsAcute critical illnessIntensive insulin therapyProspective clinical trialsIntravenous insulin protocolThoracic aorta aneurysmSevere insulin resistanceUnits of insulinCritical illnessInsulin protocolICU patientsSurgical repairBlood sugarAorta aneurysmClinical trialsPatientsTherapyPressorAneurysmsGlucocorticoidsIllness
2007
Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow?
Etz CD, Homann T, Silovitz D, Bodian CA, Luehr M, Di Luozzo G, Plestis KA, Griepp RB. Vascular Graft Replacement of the Ascending and Descending Aorta: Do Dacron Grafts Grow? The Annals Of Thoracic Surgery 2007, 84: 1206-1213. PMID: 17888971, DOI: 10.1016/j.athoracsur.2007.05.034.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAortaAorta, ThoracicAortic DiseasesBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationChildCohort StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPolyethylene TerephthalatesProbabilityProsthesis DesignProsthesis FailureReoperationRetrospective StudiesRisk AssessmentSurvival RateTreatment OutcomeConceptsDacron graftThoracic aortaGraft expansionPostoperative computed tomography scansAortic valve-sparing proceduresDevelopment of regurgitationDiseased aortic segmentMedian graft diameterRoutine postoperative surveillanceType III endoleakValve-sparing proceduresComputed tomography scanEntire thoracic aortaComputed tomography studyDacron vascular graftsVascular Dacron graftsVascular graft replacementAorta graftThoracoabdominal aneurysmsEndoluminal repairGraft replacementPostoperative surveillanceDescending AortaGraft diameterAortic segmentsAortic root reconstruction with a bioprosthetic valved conduit: A consecutive series of 275 procedures
Etz CD, Homann TM, Rane N, Bodian CA, Di Luozzo G, Plestis KA, Spielvogel D, Griepp RB. Aortic root reconstruction with a bioprosthetic valved conduit: A consecutive series of 275 procedures. Journal Of Thoracic And Cardiovascular Surgery 2007, 133: 1455-1463. PMID: 17532939, DOI: 10.1016/j.jtcvs.2007.01.058.Peer-Reviewed Original ResearchConceptsBioprosthetic valved conduitAortic root reconstructionValved conduitRoot reconstructionExtensive arch reconstructionOpen distal anastomosisPostoperative mortality rateAortic root replacementPatients 12 yearsRate of strokeHypothermic circulatory arrestLong-term outcomesLong-term survivalDegenerative aneurysmsHemiarch reconstructionHospital mortalityPermanent strokeAtherosclerotic aneurysmsRoot replacementArch reconstructionCirculatory arrestDistal anastomosisAdditional patientsDacron graftSignificant hemorrhagePulmonary Complications After Descending Thoracic and Thoracoabdominal Aortic Aneurysm Repair: Predictors, Prevention, and Treatment
Etz CD, Di Luozzo G, Bello R, Luehr M, Khan MZ, Bodian CA, Griepp RB, Plestis KA. Pulmonary Complications After Descending Thoracic and Thoracoabdominal Aortic Aneurysm Repair: Predictors, Prevention, and Treatment. The Annals Of Thoracic Surgery 2007, 83: s870-s876. PMID: 17257944, DOI: 10.1016/j.athoracsur.2006.10.099.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAortic Aneurysm, AbdominalAortic Aneurysm, ThoracicAortic RuptureBlood Urea NitrogenFemaleHemorrhageHospital MortalityHumansIntubation, IntratrachealLength of StayMaleMiddle AgedPlatelet TransfusionPrognosisRespiration DisordersRespiration, ArtificialTracheostomyVascular Surgical ProceduresConceptsPreoperative blood urea nitrogenThoracoabdominal aortic aneurysm repairDeep hypothermic circulatory arrestAortic aneurysm repairBlood urea nitrogenHospital stayPulmonary complicationsRespiratory complicationsIndependent predictorsAneurysm repairUrea nitrogenDistal aortic perfusionPreoperative renal insufficiencyProlonged postoperative ventilationMedian hospital stayPostoperative pulmonary complicationsAortic aneurysm surgeryProlonged hospital stayHypothermic circulatory arrestTransfusion of plateletsCurrent retrospective studyFemorofemoral bypassPostoperative ventilationHospital deathPostoperative bleeding
2004
Harmonic scalpel for pericardiectomy: novel approach to an old cardiac dilemma.
Di Luozzo G, Moussa F, Schor J, Traad E, Williams D, Carrillo R. Harmonic scalpel for pericardiectomy: novel approach to an old cardiac dilemma. The Heart Surgery Forum 2004, 7: e525-7. PMID: 15799939, DOI: 10.1532/hsf98.20041091.Peer-Reviewed Original ResearchConceptsUrgent cardiopulmonary bypassHarmonic scalpelCardiopulmonary bypassAdditional cardiac proceduresBloodless operative fieldCardiac traumaBlood transfusionMalignant arrhythmiasRetrospective reviewCardiac lacerationsExcessive bleedingCardiac proceduresDense adhesionsBlood productsPericardiectomyPatientsCalcific pericarditisOperative fieldBypassAdhesiolysisBleedingScalpelMortalityEpicardial surfacePericarditis