2024
The cascade of care for commercially-insured persons with opioid use disorder and comorbid HIV and HCV infections
Ivasiy R, Madden L, DiDomizio E, Johnson K, Machavariani E, Ahmad B, Oliveros D, Ram A, Kil N, Altice F. The cascade of care for commercially-insured persons with opioid use disorder and comorbid HIV and HCV infections. Drug And Alcohol Dependence 2024, 263: 112410. PMID: 39159600, DOI: 10.1016/j.drugalcdep.2024.112410.Peer-Reviewed Original ResearchOpioid use disorderXR-NTXUse disorderHCV infectionPrescribed MOUDOpioid use disorder cascadePrevalence of opioid use disorderRetrospective cohort studyHigher treatment retentionCascade of careConcurrent infectious diseasesSix-month retentionHCV/HIV coinfectionComorbid HIVCohort studyHospital-based settingPrescribed methadoneHCVMOUD initiationHIVHCV epidemicOpioidMethadoneMOUD prescriptionsTreatment retention
2022
Impact of prerelease methadone on mortality among people with HIV and opioid use disorder after prison release: results from a randomized and participant choice open-label trial in Malaysia
Bazazi A, Culbert G, Wegman M, Heimer R, Kamarulzaman A, Altice F. Impact of prerelease methadone on mortality among people with HIV and opioid use disorder after prison release: results from a randomized and participant choice open-label trial in Malaysia. BMC Infectious Diseases 2022, 22: 837. PMID: 36368939, PMCID: PMC9652918, DOI: 10.1186/s12879-022-07804-6.Peer-Reviewed Original ResearchConceptsOpioid use disorderOpioid agonist therapyInfectious etiologyMost deathsUse disordersSample of menPrison releaseOpen-label trialT-lymphocyte countsPredictors of mortalityNational death recordsCrude mortality rateProportional hazards modelCovariate-adjusted modelsLow CD4Methadone initiationModified intentionAgonist therapySurvival benefitTreat analysisMethodsThis studyHIVHazards modelMortality rateMethadoneA pilot implementation study to scale-up methadone in incarcerated persons with opioid use disorder and retain them on treatment after release in Moldova
Dorgay CE, Bromberg DJ, Doltu S, Litz T, Galvez S, Polonsky M, Dvoryak S, Altice FL. A pilot implementation study to scale-up methadone in incarcerated persons with opioid use disorder and retain them on treatment after release in Moldova. International Journal Of Drug Policy 2022, 104: 103683. PMID: 35417790, PMCID: PMC9827420, DOI: 10.1016/j.drugpo.2022.103683.Peer-Reviewed Original ResearchConceptsMethadone maintenance treatmentOpioid use disorderUse disordersBrief interventionPilot implementation studySBIRT interventionTreatment initiationMaintenance treatmentMethadonePotential implementation strategiesIncarcerated personsInterventionImplementation studyTreatment proceduresBaselineDisordersTreatmentParticipantsDays of releaseReleaseImplementation strategiesPre-trial detention facilitySessionsHIVReferral
2021
Methadone within prison and linkage to and retention in treatment upon community release for people with opioid use disorder in Kyrgyzstan: Evaluation of a national program
Bachireddy C, Shrestha R, Bromberg DJ, Azbel L, Kurmanalieva A, Wegman M, Shumskaya N, Rozanova J, Meyer JP, Altice FL. Methadone within prison and linkage to and retention in treatment upon community release for people with opioid use disorder in Kyrgyzstan: Evaluation of a national program. International Journal Of Drug Policy 2021, 101: 103558. PMID: 34915426, PMCID: PMC9998103, DOI: 10.1016/j.drugpo.2021.103558.Peer-Reviewed Original ResearchConceptsHIV statusMean treatment durationOpioid use disorderPositive HIV statusDuration of treatmentMethadone doseHIV incidenceMethadone servicesMethadone treatmentIndependent correlatesHIV preventionUse disordersTreatment durationMethadoneNational programTreatmentHIVAdministrative dataCommunity releaseMonthsKyrgyz prisonsFirst evaluationIncarcerated peopleDurationReleaseUse of Pre-exposure Prophylaxis Among People Who Inject Drugs: Exploratory Findings of the Interaction Between Race, Homelessness, and Trust
Zhou X, Altice FL, Chandra D, Didomizio E, Copenhaver MM, Shrestha R. Use of Pre-exposure Prophylaxis Among People Who Inject Drugs: Exploratory Findings of the Interaction Between Race, Homelessness, and Trust. AIDS And Behavior 2021, 25: 3743-3753. PMID: 33751313, DOI: 10.1007/s10461-021-03227-7.Peer-Reviewed Original ResearchConceptsPre-exposure prophylaxisPrEP useProvider trustPatient-level factorsOpioid-dependent patientsLogistic regression analysisNon-homeless participantsHomeless participantsRace/ethnicityEligibility criteriaCross-sectional dataPrEPProphylaxisMethadoneRegression analysisDrugsExploratory findingsParticipantsPotential moderatorsPWIDPatientsSignificant moderator
2020
A qualitative study of diphenhydramine injection in Kyrgyz prisons and implications for harm reduction
Meyer JP, Culbert GJ, Azbel L, Bachireddy C, Kurmanalieva A, Rhodes T, Altice FL. A qualitative study of diphenhydramine injection in Kyrgyz prisons and implications for harm reduction. Harm Reduction Journal 2020, 17: 86. PMID: 33129341, PMCID: PMC7603760, DOI: 10.1186/s12954-020-00435-7.Peer-Reviewed Original ResearchConceptsNeedle/syringe programsMethadone maintenance therapyHIV prevention effortsMental health consequencesDiphenhydramine injectionMaintenance therapyOpioid dependenceHIV transmissionState of euphoriaSyringe programsIllicit injectionSkin infectionsMethadone utilizationStudy participantsHarmful drugsHealth consequencesMethadonePrevention effortsHarm reductionAntihistaminesInjectionFurther investigationKyrgyz prisonsVisible woundsQualitative study
2018
Adherence to Antiretroviral Therapy Among Incarcerated Persons with HIV: Associations with Methadone and Perceived Safety
Culbert GJ, Waluyo A, Wang M, Putri TA, Bazazi AR, Altice FL. Adherence to Antiretroviral Therapy Among Incarcerated Persons with HIV: Associations with Methadone and Perceived Safety. AIDS And Behavior 2018, 23: 2048-2058. PMID: 30465106, PMCID: PMC6698149, DOI: 10.1007/s10461-018-2344-6.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyART adherenceART utilizationMethadone utilizationHIV status disclosureHealth service satisfactionStatus disclosureMedical treatmentDrug dependencyPWHAdherenceMost participantsHIVMethadoneTherapyChance locusSafetyAdequate supportHigh levelsPerceived SafetyPersonal safetyPerceptions of Health-Related Community Reentry Challenges among Incarcerated Drug Users in Azerbaijan, Kyrgyzstan, and Ukraine
Rozanova J, Morozova O, Azbel L, Bachireddy C, Izenberg JM, Kiriazova T, Dvoryak S, Altice FL. Perceptions of Health-Related Community Reentry Challenges among Incarcerated Drug Users in Azerbaijan, Kyrgyzstan, and Ukraine. Journal Of Urban Health 2018, 95: 508-522. PMID: 29728898, PMCID: PMC6095752, DOI: 10.1007/s11524-018-0256-4.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentSubstance use disordersUse disordersMethadone treatmentDrug usersPoor general healthGeneral health conditionPerception of healthAgonist treatmentDrug injectionGeneral healthHigh prevalenceHealth needsHealth-related tasksLogistic regressionMethadoneHealth conditionsPre-release planningDisordersTreatmentPublic healthTotal samplePrison settingDrugsHealth
2017
Why People Who Inject Drugs Voluntarily Transition Off Methadone in Ukraine
Rozanova J, Marcus R, Taxman FS, Bojko MJ, Madden L, Farnum SO, Mazhnaya A, Dvoriak S, Altice FL. Why People Who Inject Drugs Voluntarily Transition Off Methadone in Ukraine. Qualitative Health Research 2017, 27: 2057-2070. PMID: 28942704, DOI: 10.1177/1049732317732307.Peer-Reviewed Original Research
2016
Attitudes toward medication-assisted treatment among fishermen in Kuantan, Malaysia, who inject drugs
Brown SE, Wickersham JA, Pelletier AR, Marcus RM, Erenrich R, Kamarulzaman A, Altice FL. Attitudes toward medication-assisted treatment among fishermen in Kuantan, Malaysia, who inject drugs. Journal Of Ethnicity In Substance Abuse 2016, 16: 363-379. PMID: 27404914, PMCID: PMC5592158, DOI: 10.1080/15332640.2016.1196632.Peer-Reviewed Original ResearchAttitudes Toward Addiction, Methadone Treatment, and Recovery Among HIV-Infected Ukrainian Prisoners Who Inject Drugs: Incarceration Effects and Exploration of Mediators
Polonsky M, Rozanova J, Azbel L, Bachireddy C, Izenberg J, Kiriazova T, Dvoryak S, Altice FL. Attitudes Toward Addiction, Methadone Treatment, and Recovery Among HIV-Infected Ukrainian Prisoners Who Inject Drugs: Incarceration Effects and Exploration of Mediators. AIDS And Behavior 2016, 20: 2950-2960. PMID: 27011378, PMCID: PMC5035551, DOI: 10.1007/s10461-016-1375-0.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyGroup 1Drug useGroup 2 participantsDrug addiction severityAwareness of addictionMaintenance therapyMethadone treatmentExploration of mediatorsHIV stigmaGroup 2MMT treatmentAddiction severityGroup comparisonsDrug addictionHIVHigh rateAddictionHigher optimismDrugsTreatmentParticipantsMethadoneGroupPaper’s key findings
2015
Treatment Readiness, Attitudes Toward, and Experiences with Methadone and Buprenorphine Maintenance Therapy Among People Who Inject Drugs in Malaysia
Vijay A, Bazazi AR, Yee I, Kamarulzaman A, Altice FL. Treatment Readiness, Attitudes Toward, and Experiences with Methadone and Buprenorphine Maintenance Therapy Among People Who Inject Drugs in Malaysia. Journal Of Substance Use And Addiction Treatment 2015, 54: 29-36. PMID: 25841703, PMCID: PMC4758679, DOI: 10.1016/j.jsat.2015.01.014.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAge of OnsetAgedAttitudeBuprenorphineEthnicityFemaleHumansMalaysiaMaleMethadoneMiddle AgedNarcoticsNeedle SharingNeedle-Exchange ProgramsOpiate Substitution TreatmentPatient Acceptance of Health CareStress, PsychologicalSubstance Abuse Treatment CentersSubstance Abuse, IntravenousYoung AdultConceptsOpioid maintenance therapyBuprenorphine maintenance therapyMaintenance therapyTreatment readinessNeedle/syringe exchange programsSharing of needlesMultivariable linear regressionSyringe exchange programsCompulsory drug detention centersMajority of subjectsReadiness scoresOpioid dependencePatients' attitudesPrimary careMethadoneTreatment settingsStress symptom severityBuprenorphineIndian ethnicityAdult populationSymptom severityOlder agePast monthTherapyDrugs
2013
A review of pharmacological interactions between HIV or hepatitis C virus medications and opioid agonist therapy: implications and management for clinical practice
Bruce RD, Moody DE, Altice FL, Gourevitch MN, Friedland GH. A review of pharmacological interactions between HIV or hepatitis C virus medications and opioid agonist therapy: implications and management for clinical practice. Expert Review Of Clinical Pharmacology 2013, 6: 249-269. PMID: 23656339, PMCID: PMC4198941, DOI: 10.1586/ecp.13.18.Peer-Reviewed Original ResearchConceptsOpioid agonist therapyAntiretroviral therapyDrug interactionsAgonist therapyHIV medicationsHepatitis C virus medicationsHepatitis C virus (HCV) treatmentActive antiretroviral therapyC virus treatmentPharmacodynamic drug interactionsImportant clinical consequencesReview of abstractsHCV therapyAntiretroviral agentsPharmacodynamic interactionsPharmacological interactionsHIV therapyClinical consequencesVirus treatmentClinical practiceFollowing keywordsTherapyClinical implicationsMedicationsMethadoneImplementing methadone maintenance treatment in prisons in Malaysia
Wickersham JA, Marcus R, Kamarulzaman A, Zahari MM, Altice FL. Implementing methadone maintenance treatment in prisons in Malaysia. Bulletin Of The World Health Organization 2013, 91: 124-129. PMID: 23554524, PMCID: PMC3605007, DOI: 10.2471/blt.12.109132.Peer-Reviewed Original ResearchConceptsDose of methadoneMMT programHIV infectionHuman immunodeficiency virus (HIV) infectionMethadone maintenance treatment programDaily oral doseImmunodeficiency virus infectionMethadone maintenance treatmentMaintenance treatment programHarm reduction strategiesMinistry of HealthAdequate dosingOral doseMaintenance treatmentMethadone treatmentStandard operating proceduresMMT clientsVirus infectionTreatment programMethadoneOngoing educationInfectionDosePhase 3Tuberculosis
2011
Pharmacokinetic drug interactions and adverse consequences between psychotropic medications and pharmacotherapy for the treatment of opioid dependence
Saber-Tehrani AS, Bruce RD, Altice FL. Pharmacokinetic drug interactions and adverse consequences between psychotropic medications and pharmacotherapy for the treatment of opioid dependence. The American Journal Of Drug And Alcohol Abuse 2011, 37: 1-11. PMID: 21247284, DOI: 10.3109/00952990.2010.540279.Peer-Reviewed Original ResearchConceptsPharmacokinetic drug interactionsDrug interactionsOpioid dependencePsychotropic medicationsPsychoactive medicationsImportant pharmacokinetic drug interactionsClasses of medicationsOpioid-dependent patientsRelevant English-language articlesClinical case seriesMedication-assisted treatmentCytochrome P450 isoenzymesImportant clinical consequencesEnglish-language articlesPharmacokinetic interaction studyCase seriesPsychiatric comorbidityEmbase databasesClinical consequencesMedicationsP450 isoenzymesBuprenorphineMethadoneLanguage articlesPsychoactive drugs
2007
Pharmacological Treatment of Substance Abuse in Correctional Facilities: Prospects and Barriers to Expanding Access to Evidence-Based Therapy
Bruce R, Smith-Rohrberg D, Altice F. Pharmacological Treatment of Substance Abuse in Correctional Facilities: Prospects and Barriers to Expanding Access to Evidence-Based Therapy. 2007, 385-411. DOI: 10.1007/978-0-387-71695-4_23.Peer-Reviewed Original ResearchPharmacological treatmentSubstance abuseSerious public health concernEvidence-based therapiesTreatment of cocainePublic health concernCorrectional health careAvailable medicationsMethamphetamine abuseHealth concernNew drugsHealth careChemical dependencyTreatmentIncarcerated populationsAbuseCorrectional facilitiesMedicationsBuprenorphinePharmacotherapyNaltrexoneMethadoneTherapyDisulfiramCare
2006
Pharmacokinetic Drug Interactions Between Opioid Agonist Therapy and Antiretroviral Medications
Bruce RD, Altice FL, Gourevitch MN, Friedland GH. Pharmacokinetic Drug Interactions Between Opioid Agonist Therapy and Antiretroviral Medications. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2006, 41: 563-572. PMID: 16652030, DOI: 10.1097/01.qai.0000219769.89679.ec.Peer-Reviewed Original ResearchConceptsPharmacokinetic drug interactionsOpioid agonist therapyDrug interactionsAgonist therapyAntiretroviral therapyAntiretroviral medicationsImportant pharmacokinetic drug interactionsClinical case seriesImportant clinical consequencesClass of agentsHIV/AIDSPharmacokinetic interaction studyAntiretroviral agentsCase seriesOpioid dependenceHIV treatmentTreatable diseaseHIV therapyClinical consequencesFollowing keywordsMethadoneTherapyClinical implicationsLanguage articlesMedications