2022
mHealth Intervention to Improve Treatment Outcomes Among People With HIV Who Use Cocaine: Protocol for a Pilot Randomized Controlled Trial
Ranjit YS, Krishnan A, Ghosh D, Cravero C, Zhou X, Altice FL. mHealth Intervention to Improve Treatment Outcomes Among People With HIV Who Use Cocaine: Protocol for a Pilot Randomized Controlled Trial. JMIR Research Protocols 2022, 11: e28332. PMID: 35254270, PMCID: PMC8938831, DOI: 10.2196/28332.Peer-Reviewed Original ResearchINTERNATIONAL REGISTERED REPORT IDENTIFIERMobile health interventionsAntiretroviral therapyTreatment outcomesHealth interventionsHIV treatment outcomesInstitutional review boardTechnology-based interventionsControlled TrialsHIV servicesMedication adherenceStudy populationElectronic pillboxMulticomponent interventionUse cocaineAdherence behaviorHIVMHealth interventionsFinal enrollmentReview boardStudy designDrug abuse
2020
Assessing mobile health feasibility and acceptability among HIV-infected cocaine users and their healthcare providers: guidance for implementing an intervention
Brown SE, Krishnan A, Ranjit YS, Marcus R, Altice FL. Assessing mobile health feasibility and acceptability among HIV-infected cocaine users and their healthcare providers: guidance for implementing an intervention. MHealth 2020, 6: 4-4. PMID: 32190615, PMCID: PMC7063267, DOI: 10.21037/mhealth.2019.09.12.Peer-Reviewed Original ResearchMedication adherenceHealthcare providersCocaine useFeasibility of mHealthHIV treatment outcomesCocaine usersCommunity health workersSelf-reported cocaine usePatient-provider relationshipPhone callsPharmacological treatmentText remindersTreatment outcomesHealth workersControl trialFocus groupsMHealth interventionsPatientsHIVMHealth pilotsCost-effective strategyCase managersHealth informationHealth purposesAdherence
2019
HIV-Related Stigma, Motivation to Adhere to Antiretroviral Therapy, and Medication Adherence Among HIV-Positive Methadone-Maintained Patients
Shrestha R, Altice FL, Copenhaver MM. HIV-Related Stigma, Motivation to Adhere to Antiretroviral Therapy, and Medication Adherence Among HIV-Positive Methadone-Maintained Patients. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 80: 166-173. PMID: 30383588, PMCID: PMC6331231, DOI: 10.1097/qai.0000000000001891.Peer-Reviewed Original ResearchConceptsOptimal ART adherenceAntiretroviral therapyMethadone-maintained patientsMethadone maintenance treatmentART adherenceMaintenance treatmentHIV treatment outcomesHIV-positive patientsOpioid agonist therapyMultivariable logistic regressionHIV risk behaviorsExplanatory pathwaysAgonist therapySuboptimal adherenceMedication adherenceHIV treatmentTreatment outcomesHIV stigmaPatientsLogistic regressionHIVPrevention initiativesTherapyAdherenceSignificant correlates
2017
Predictors of linkage to HIV care and viral suppression after release from jails and prisons: a retrospective cohort study
Loeliger KB, Altice FL, Desai MM, Ciarleglio MM, Gallagher C, Meyer JP. Predictors of linkage to HIV care and viral suppression after release from jails and prisons: a retrospective cohort study. The Lancet HIV 2017, 5: e96-e106. PMID: 29191440, PMCID: PMC5807129, DOI: 10.1016/s2352-3018(17)30209-6.Peer-Reviewed Original ResearchConceptsHIV treatment outcomesHIV careViral suppressionTreatment outcomesPoor HIV treatment outcomesMore medical comorbiditiesPost-release linkagePredictors of linkageRetrospective cohort studyDetectable viral loadCase management servicesCase management dataTransitional case managementHealth care goalsAntiretroviral therapyMedical comorbiditiesCohort studyRetrospective cohortDays of releaseViral loadPharmacy databasePsychiatric comorbidityUS National InstitutesCase management needsHispanic ethnicityPredictors of Linkage to and Retention in HIV Care Following Release from Connecticut Jails and Prisons
Loeliger K, Altice F, Desai M, Ciarleglio M, Gallagher C, Meyer J. Predictors of Linkage to and Retention in HIV Care Following Release from Connecticut Jails and Prisons. Open Forum Infectious Diseases 2017, 4: s38-s38. PMCID: PMC5632019, DOI: 10.1093/ofid/ofx162.092.Peer-Reviewed Original ResearchTime of linkageHIV-1 RNA testsCase managementHigher medical comorbidityPredictors of linkageViral suppression statusHIV treatment outcomesCase management dataPrior observational studiesTransitional case managementHIV careMedical comorbiditiesViral suppressionDetectable viremiaRetrospective cohortHIV outcomesRNA testIndependent correlatesPsychiatric comorbidityIncarceration periodsTreatment outcomesObservational studySuppression statusTargeted interventionsComorbiditiesAssessing Feasibility and Acceptability of mHealth among Underserved HIV+ Cocaine Users and Their Healthcare Providers
Brown S, Krishnan A, Ranjit Y, Marcus R, Altice F. Assessing Feasibility and Acceptability of mHealth among Underserved HIV+ Cocaine Users and Their Healthcare Providers. Iproceedings 2017, 3: e48. DOI: 10.2196/iproc.8676.Peer-Reviewed Original ResearchGroup of HIVText remindersCocaine usersDrug treatment clinicsFeasibility of mHealthHIV treatment outcomesSelf-reported cocaine useRisk of transmissionAcceptability of mHealthPhone callsViral suppressionAntiretroviral medicationsMobile medical unitsUnstable living conditionsHIV statusMedication adherenceSubstance use providersTreatment clinicsTreatment outcomesPharmacological interventionsControl trialHIVAdherence behaviorMHealth interventionsHealth behaviorsDesign and implementation of a factorial randomized controlled trial of methadone maintenance therapy and an evidence-based behavioral intervention for incarcerated people living with HIV and opioid dependence in Malaysia
Bazazi AR, Wickersham JA, Wegman MP, Culbert GJ, Pillai V, Shrestha R, Al-Darraji H, Copenhaver MM, Kamarulzaman A, Altice FL. Design and implementation of a factorial randomized controlled trial of methadone maintenance therapy and an evidence-based behavioral intervention for incarcerated people living with HIV and opioid dependence in Malaysia. Contemporary Clinical Trials 2017, 59: 1-12. PMID: 28479216, PMCID: PMC5557499, DOI: 10.1016/j.cct.2017.05.006.Peer-Reviewed Original ResearchConceptsMethadone maintenance therapyHIV transmission risk behaviorsMaintenance therapyTransmission risk behaviorsEvidence-based behavioral interventionsOpioid dependencePoor HIV treatment outcomesRisk behaviorsBehavioral interventionsHIV treatment outcomesProspective clinical trialsEvidence-based treatmentsHealth-related outcomesOpioid useTreatment receiptClinical trialsTreatment outcomesIncarcerated peopleTherapyStudy participantsFactorial trialHIVTrialsInterventionOutcomesA Self-report Measure to Detect Neurocognitive Impairment Among Incarcerated People Living with HIV in Malaysian Context: an Exploratory Factor Analysis
Shrestha R, Weikum D, Copenhaver M, Altice FL. A Self-report Measure to Detect Neurocognitive Impairment Among Incarcerated People Living with HIV in Malaysian Context: an Exploratory Factor Analysis. International Journal Of Mental Health And Addiction 2017, 15: 812-825. PMID: 29051714, PMCID: PMC5642920, DOI: 10.1007/s11469-017-9752-0.Peer-Reviewed Original ResearchNeuropsychological Impairment ScaleNeurocognitive impairmentHIV treatment outcomesNeuro-cognitive impairmentExploratory factor analysisSelf-report measuresNeurocognitive symptomsTreatment outcomesTreatment strategiesImpairment ScaleHIVScreening toolImpairmentPLWHEight-factor structureCronbach's alphaPrincipal axis factoringCognitive functioningOrthogonal varimax rotationPsychometric propertiesDrugsPresent studyMale prisonersIncarcerated peopleMore specific forms
2015
HIV-infected men who have sex with men, before and after release from jail: the impact of age and race, results from a multi-site study
Vagenas P, Zelenev A, Altice FL, Di Paola A, Jordan AO, Teixeira PA, Frew PM, Spaulding AC, Springer SA. HIV-infected men who have sex with men, before and after release from jail: the impact of age and race, results from a multi-site study. AIDS Care 2015, 28: 22-31. PMID: 26275122, PMCID: PMC4713253, DOI: 10.1080/09540121.2015.1062464.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAnti-HIV AgentsBlack or African AmericanBlack PeopleContinuity of Patient CareHealth Services AccessibilityHealthcare DisparitiesHIV InfectionsHomosexuality, MaleHumansInsurance, HealthKaplan-Meier EstimateMalePrisonersPrisonsRacial GroupsTreatment OutcomeYoung AdultConceptsBlack MSMHIV healthcare providersHIV treatment outcomesDisease management interventionsHIV/AIDS epidemicYoung Black MSMImpact of ageNon-black MSMHigher infection rateYoung HIVTreatment outcomesLarge cohortWorst HIVHIVHealth outcomesJail detaineesMale subgroupHealthcare providersInfection rateMulti-site studyMSMAIDS epidemicMenBlack menInterventionSex-Related Disparities in Criminal Justice and HIV Treatment Outcomes: A Retrospective Cohort Study of HIV-Infected Inmates.
Meyer JP, Cepeda J, Taxman FS, Altice FL. Sex-Related Disparities in Criminal Justice and HIV Treatment Outcomes: A Retrospective Cohort Study of HIV-Infected Inmates. American Journal Of Public Health 2015, 105: 1901-10. PMID: 26180958, PMCID: PMC4529767, DOI: 10.2105/ajph.2015.302687.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyViral suppressionSex-related differencesHigh prevalenceRisk scoreHIV treatment outcomesRetrospective cohort studyHIV viral suppressionLarge contemporary cohortSex-related disparitiesSex-specific interventionsCommunity-based treatmentWomen's higher prevalenceLogistic regression modelsCJ populationsTreatable comorbiditiesCohort studyHIV outcomesContemporary cohortTreatment outcomesHIVCJ involvementIncarceration durationOlder ageSignificant correlatesChallenges in managing HIV in people who use drugs
Kamarulzaman A, Altice FL. Challenges in managing HIV in people who use drugs. Current Opinion In Infectious Diseases 2015, 28: 10-16. PMID: 25490106, PMCID: PMC4409950, DOI: 10.1097/qco.0000000000000125.Peer-Reviewed Original ResearchMeSH KeywordsAnti-HIV AgentsCoinfectionComorbidityContinuity of Patient CareHealth Services AccessibilityHepatitis CHIV InfectionsHumansMedication AdherenceMental DisordersNeedle-Exchange ProgramsOpiate Substitution TreatmentSocial ClassSubstance Abuse, IntravenousSubstance-Related DisordersTuberculosisConceptsOpioid substitution therapyHepatitis C virusHIV continuumTreatment outcomesImproved ART adherenceInterferon-based regimesTB treatment outcomesHIV treatment outcomesBetter treatment retentionEvidence-based preventionHIV treatment accessHIV-HCVNoninfectious comorbiditiesOST servicesCare retentionART adherenceHIV managementAntiretroviral adherencePsychiatric comorbiditySubstitution therapyHIV treatmentNew diagnostic technologiesC virusClinical managementEarly diagnosis
2014
HIV in people reincarcerated in Connecticut prisons and jails: an observational cohort study
Meyer JP, Cepeda J, Springer SA, Wu J, Trestman RL, Altice FL. HIV in people reincarcerated in Connecticut prisons and jails: an observational cohort study. The Lancet HIV 2014, 1: e77-e84. PMID: 25473651, PMCID: PMC4249702, DOI: 10.1016/s2352-3018(14)70022-0.Peer-Reviewed Original ResearchViral suppressionHIV treatment outcomesInhibitor-based regimensObservational cohort studyHIV viral suppressionART regimenCohort studyRetrospective cohortPrimary outcomeViral loadPsychiatric comorbidityTreatment outcomesIdentification of individualsHIVJail detaineesLaboratory databaseTreatment potencyDrug abuseRNA copiesNational InstitutePrison releasePublic healthBlack menIncarceration periodsOutcomesCommunication technology use and mHealth acceptance among HIV-infected men who have sex with men in Peru: implications for HIV prevention and treatment
Krishnan A, Ferro EG, Weikum D, Vagenas P, Lama JR, Sanchez J, Altice FL. Communication technology use and mHealth acceptance among HIV-infected men who have sex with men in Peru: implications for HIV prevention and treatment. AIDS Care 2014, 27: 273-282. PMID: 25285464, PMCID: PMC4305474, DOI: 10.1080/09540121.2014.963014.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcohol DrinkingAnti-Retroviral AgentsCell PhoneEducationFemaleHealth SurveysHIV InfectionsHomosexuality, MaleHumansMaleMedication AdherenceMiddle AgedPeruPovertyPrevalenceRisk FactorsSexual BehaviorSurveys and QuestionnairesTelemedicineText MessagingTransgender PersonsConceptsAlcohol use disorderTransgender womenMHealth acceptancePoor HIV treatment outcomesHIV treatment outcomesAntiretroviral therapy adherenceSuboptimal ART adherenceHIV risk behaviorsART adherenceRisky sexual behaviorPeruvian MSMTherapy adherenceHIV epidemicHIV preventionTreatment outcomesHIV interventionsUse disordersMedication remindersHealth professionalsHIVMSMConvenience sampleMost participantsIntervention strategiesStandardized assessmentDesign and methods of a double blind randomized placebo-controlled trial of extended-release naltrexone for HIV-infected, opioid dependent prisoners and jail detainees who are transitioning to the community
Di Paola A, Lincoln T, Skiest DJ, Desabrais M, Altice FL, Springer SA. Design and methods of a double blind randomized placebo-controlled trial of extended-release naltrexone for HIV-infected, opioid dependent prisoners and jail detainees who are transitioning to the community. Contemporary Clinical Trials 2014, 39: 256-268. PMID: 25240704, PMCID: PMC4283549, DOI: 10.1016/j.cct.2014.09.002.Peer-Reviewed Original ResearchConceptsOpioid agonist treatmentPlacebo-controlled trialXR-NTXAgonist treatmentOpioid dependenceTreatment outcomesPoor HIV treatment outcomesOpioid treatment outcomesOpioid-dependent prisonersExtended-release naltrexoneHIV treatment outcomesHIV transmission riskEvidence-based treatmentsCriminal justice settingsEarly acceptabilityStudy medicationFirst injectionStudy acceptabilityHIVTotal referralsJail detaineesCommunity settingsTransmission riskDrug relapseHigh internal validityOptimization of Human Immunodeficiency Virus Treatment During Incarceration: Viral Suppression at the Prison Gate
Meyer JP, Cepeda J, Wu J, Trestman RL, Altice FL, Springer SA. Optimization of Human Immunodeficiency Virus Treatment During Incarceration: Viral Suppression at the Prison Gate. JAMA Internal Medicine 2014, 174: 721-729. PMID: 24687044, PMCID: PMC4074594, DOI: 10.1001/jamainternmed.2014.601.Peer-Reviewed Original ResearchConceptsHIV-1 RNA levelsCD4 lymphocyte countViral suppressionHIV viral suppressionLymphocyte countObserved therapyRNA levelsBaseline HIV-1 RNA levelsMean HIV-1 RNA levelHuman immunodeficiency virus (HIV) treatmentHuman immunodeficiency virus managementHIV treatment outcomesRetrospective cohort studyAntiretroviral therapy regimensHIV-1 RNAPsychiatric disorder severityLogistic regression modelsCommunity-based resourcesDuration of incarcerationRace/ethnicityART regimenContinuous ARTPrescribed pharmacotherapyAntiretroviral therapyART regimensGender disparities in HIV treatment outcomes following release from jail: results from a multicenter study.
Meyer JP, Zelenev A, Wickersham JA, Williams CT, Teixeira PA, Altice FL. Gender disparities in HIV treatment outcomes following release from jail: results from a multicenter study. American Journal Of Public Health 2014, 104: 434-41. PMID: 24432878, PMCID: PMC3953795, DOI: 10.2105/ajph.2013.301553.Peer-Reviewed Original ResearchConceptsHIV treatment outcomesTreatment outcomesViral suppressionJail detaineesMultisite prospective cohort studyOptimal antiretroviral therapy (ART) adherenceOptimal HIV treatment outcomesWorse HIV treatment outcomesMultiple logistic regression modelAntiretroviral therapy prescriptionHIV primary careHIV clinical careProspective cohort studyAntiretroviral therapy adherenceNon-Hispanic whitesLogistic regression modelsGreater comorbidityCohort studyEvaluable participantsMulticenter studyTherapy adherencePrimary careTherapy prescriptionClinical careHeroin use
2013
Design and methods of a double blind randomized placebo-controlled trial of extended-release naltrexone for alcohol dependent and hazardous drinking prisoners with HIV who are transitioning to the community
Springer SA, Altice FL, Herme M, Di Paola A. Design and methods of a double blind randomized placebo-controlled trial of extended-release naltrexone for alcohol dependent and hazardous drinking prisoners with HIV who are transitioning to the community. Contemporary Clinical Trials 2013, 37: 209-218. PMID: 24384538, PMCID: PMC3992862, DOI: 10.1016/j.cct.2013.12.006.Peer-Reviewed Original ResearchConceptsPlacebo-controlled trialHIV treatment outcomesTreatment outcomesCriminal justice system (CJS) populationsPoor antiretroviral therapy (ART) adherenceAlcohol useExtended-release naltrexoneAntiretroviral therapy adherenceMedication-assisted therapyPrevention of relapseAlcohol use disorderSexual risk-taking behaviorsAlcohol-dependent personsXR-NTXHigh morbidityTherapy adherenceAlcohol relapseHigh prevalenceStudy participationEligibility criteriaUse disordersHIVRelapseHazardous drinkingNaltrexonePartner violence and health among HIV-infected jail detainees
Meyer JP, Wickersham JA, Fu JJ, Brown SE, Sullivan TP, Springer SA, Altice FL. Partner violence and health among HIV-infected jail detainees. International Journal Of Prison Health 2013, 9: 124-141. PMID: 24376468, PMCID: PMC3873166, DOI: 10.1108/ijph-03-2013-0011.Peer-Reviewed Original ResearchConceptsIntimate partner violenceSubstance use disordersHIV treatment outcomesHealthcare utilizationPartner violenceTreatment outcomesJail detaineesIPV exposureEffects of IPVHIV secondary preventionPost-release interventionsUntreated mental disordersDepth qualitative interviewsLifetime IPV exposureForms of childhoodHigher alcohol use severityCriminal justice populationsAlcohol use severityViolence reductionCJ populationsTime of incarcerationHIV diagnosisSecondary preventionAdulthood abuseQualitative interviewsOptimizing Care for HIV-Infected People Who Use Drugs: Evidence-Based Approaches to Overcoming Healthcare Disparities
Meyer JP, Althoff AL, Altice FL. Optimizing Care for HIV-Infected People Who Use Drugs: Evidence-Based Approaches to Overcoming Healthcare Disparities. Clinical Infectious Diseases 2013, 57: 1309-1317. PMID: 23797288, PMCID: PMC3792721, DOI: 10.1093/cid/cit427.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsHuman immunodeficiency virusSubstance use disordersAntiretroviral therapyHealthcare disparitiesInitiation of ARTComorbid substance use disorderHIV treatment outcomesContinuum of careEvidence-based strategiesEvidence-based approachHIV specialistsHIV careHIV diagnosisImmunodeficiency virusTreatment outcomesUse disordersSubstance useCareDiagnosisDrugsOutcomesDisparitiesNegative outcomesTherapyEpidemiologyContribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail
Chitsaz E, Meyer JP, Krishnan A, Springer SA, Marcus R, Zaller N, Jordan AO, Lincoln T, Flanigan TP, Porterfield J, Altice FL. Contribution of Substance Use Disorders on HIV Treatment Outcomes and Antiretroviral Medication Adherence Among HIV-Infected Persons Entering Jail. AIDS And Behavior 2013, 17: 118-127. PMID: 23673792, PMCID: PMC3818019, DOI: 10.1007/s10461-013-0506-0.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlcohol DrinkingAnti-Retroviral AgentsComorbidityCross-Sectional StudiesFemaleHIV InfectionsHumansLogistic ModelsMaleMedication AdherenceMiddle AgedPrisonersPrisonsSocioeconomic FactorsSubstance Abuse, IntravenousSubstance-Related DisordersTreatment OutcomeUnited StatesYoung AdultConceptsAntiretroviral medication adherenceSubstance use disordersMedication adherenceUse disordersEvidence-based drug treatmentHIV care providersHIV treatment engagementHIV treatment outcomesMedication-assisted therapyMulti-faceted interventionPaucity of evidenceDrug use severityAntiretroviral therapyPoor outcomePsychiatric comorbidityHIV treatmentTreatment outcomesDrug treatmentCare providersJail detaineesTreatment engagementUS sitesSubstance useVulnerable populationsUse severity