2010
Limited Attentional Bias for Faces in Toddlers With Autism Spectrum Disorders
Chawarska K, Volkmar F, Klin A. Limited Attentional Bias for Faces in Toddlers With Autism Spectrum Disorders. JAMA Psychiatry 2010, 67: 178-185. PMID: 20124117, PMCID: PMC4871149, DOI: 10.1001/archgenpsychiatry.2009.194.Peer-Reviewed Original ResearchConceptsAttention disengagementVisual attentionRelevant stimuliDeep processingFace-processing difficultiesPoor face recognitionFace processing deficitsDisengagement of attentionCentral fixation stimulusAutism spectrum disorderSaccadic reaction timesBetween-groups factorAttentional biasSocial cognitionAttention taskAttentional mechanismsNonfacial stimuliAttentional levelStimulus typeSpectrum disorderTypical individualsReactive saccadesFixation stimulusASDGeneralized impairment
2009
A genome-wide linkage and association scan reveals novel loci for autism
Daly M, Chakravarti A, Arking D, Brune C, West K, O’Connor A, Hilton G, Tomlinson R, West A, Cook Jr E, Chakravarti A, Weiss L, Green T, Chang S, Gabriel S, Gates C, Hanson E, Kirby A, Korn J, Kuruvilla F, McCarroll S, Morrow E, Neale B, Purcell S, Sasanfar R, Sougnez C, Stevens C, Altshuler D, Gusella J, Santangelo S, Sklar P, Tanzi R, Daly M, Anney R, Bailey A, Baird G, Battaglia A, Berney T, Betancur C, Bölte S, Bolton P, Brian J, Bryson S, Buxbaum J, Cabrito I, Cai G, Cantor R, Cook Jr E, Coon H, Conroy J, Correia C, Corsello C, Crawford E, Cuccaro M, Dawson G, de Jonge M, Devlin B, Duketis E, Ennis S, Estes A, Farrar P, Fombonne E, Freitag C, Gallagher L, Geschwind D, Gilbert J, Gill M, Gillberg C, Goldberg J, Green A, Green J, Guter S, Haines J, Hallmayer J, Hus V, Klauck S, Korvatska O, Lamb J, Laskawiec M, Leboyer M, Le Couteur A, Leventhal B, Liu X, Lord C, Lotspeich L, Maestrini E, Magalhaes T, Mahoney W, Mantoulan C, McConachie H, McDougle C, McMahon W, Marshall C, Miller J, Minshew N, Monaco A, Munson J, Nurnberger Jr J, Oliveira G, Pagnamenta A, Papanikolaou K, Parr J, Paterson A, Pericak-Vance M, Pickles A, Pinto D, Piven J, Posey D, Poustka A, Poustka F, Regan R, Reichert J, Renshaw K, Roberts W, Roge B, Rutter M, Salt J, Schellenberg G, Scherer S, Sheffield V, Sutcliffe J, Szatmari P, Tansey K, Thompson A, Tsiantis J, Van Engeland H, Vicente A, Vieland V, Volkmar F, Wallace S, Wassink T, Wijsman E, Wing K, Wittemeyer K, Yaspan B, Zwaigenbaum L, Morrow E, Yoo S, Sean Hill R, Mukaddes N, Balkhy S, Gascon G, Al-Saad S, Hashmi A, Ware J, Joseph R, LeClair E, Partlow J, Barry B, Walsh C, Pauls D, Moilanen I, Ebeling H, Mattila M, Kuusikko S, Jussila K, Ignatius J, Sasanfar R, Tolouei A, Ghadami M, Rostami M, Hosseinipour A, Valujerdi M, Santangelo S, Andresen K, Winkloski B, Haddad S, Kunkel L, Kohane Z, Tran T, Won Kong S, O’Neil S, Hanson E, Hundley R, Holm I, Peters H, Baroni E, Cangialose A, Jackson L, Albers L, Becker R, Bridgemohan C, Friedman S, Munir K, Nazir R, Palfrey J, Schonwald A, Simmons E, Rappaport L, Gauthier J, Mottron L, Joober R, Fombonne E, Rouleau G, Rehnstrom K, von Wendt L, Peltonen L. A genome-wide linkage and association scan reveals novel loci for autism. Nature 2009, 461: 802-808. PMID: 19812673, PMCID: PMC2772655, DOI: 10.1038/nature08490.Peer-Reviewed Original ResearchConceptsGenome-wide SNPsSusceptibility genesGenome-wide linkageGenome-wide scanSpecific susceptibility genesAutism susceptibility genesExpression of SEMA5AHeritable neurodevelopmental disorderAssociation scanNovel lociChromosome 5p15Multiplex autism familiesLinkage regionAutism familiesSignificant linkageNovel associationsGenesSEMA5ARare variationNeurodevelopmental disordersCommon setLociSNPsExpressionTAS2R1Social Skills Interventions for Individuals with Autism: Evaluation for Evidence-Based Practices within a Best Evidence Synthesis Framework
Reichow B, Volkmar FR. Social Skills Interventions for Individuals with Autism: Evaluation for Evidence-Based Practices within a Best Evidence Synthesis Framework. Journal Of Autism And Developmental Disorders 2009, 40: 149-166. PMID: 19655240, DOI: 10.1007/s10803-009-0842-0.Peer-Reviewed Original ResearchMeSH KeywordsAutistic DisorderChildChild, PreschoolFemaleHumansMaleParentingParentsPhotic StimulationSocial BehaviorTeachingVideotape Recording
2002
Editorial Preface
Volkmar F. Editorial Preface. Journal Of Autism And Developmental Disorders 2002, 32: 1-1. PMID: 11916336, DOI: 10.1023/a:1017954721441.Peer-Reviewed Original Research
2001
Methodological Issues in Designing a Multisite Trial of Risperidone in Children and Adolescents with Autism
Scahill L, McCracken J, McDougle C, Aman M, Arnold L, Tierney E, Cronin P, Davies M, Ghuman J, Gonzalez N, Koenig K, Lindsay R, Martin A, McGough J, Posey D, Swiezy N, Volkmar F, Ritz L, Vitiello B. Methodological Issues in Designing a Multisite Trial of Risperidone in Children and Adolescents with Autism. Journal Of Child And Adolescent Psychopharmacology 2001, 11: 377-388. PMID: 11838820, DOI: 10.1089/104454601317261555.Peer-Reviewed Original ResearchConceptsPlacebo-controlled studyPlacebo-controlled discontinuation studyAutistic disorderSafety of risperidoneStudy of RisperidoneStandard pharmacological treatmentSelf-injurious behaviorDiscontinuation studyPharmacological treatmentClinical trialsInclusion criteriaLong-term effectsSevere tantrumsTrial designClinical relevanceClinical practiceLength of trialRisperidoneMultisite trialStudy designContinuous treatmentTrialsTreatment effectsDisordersMaintenance phaseSpeech and Prosody Characteristics of Adolescents and Adults With High-Functioning Autism and Asperger Syndrome
Shriberg L, Paul R, McSweeny J, Klin A, Cohen D, Volkmar F. Speech and Prosody Characteristics of Adolescents and Adults With High-Functioning Autism and Asperger Syndrome. Journal Of Speech Language And Hearing Research 2001, 44: 1097-1115. PMID: 11708530, DOI: 10.1044/1092-4388(2001/087).Peer-Reviewed Original ResearchConceptsHigh functioning autismPervasive developmental disorderAsperger syndromeDevelopmental disordersMale speakersGroups of speakersAffective aspectsTypical speakersProsody characteristicsSocial sourcesDiscourse constraintsSpeakersAutismSpeechUtterancesMore participantsDistortion errorsAge rangeProsodyDisordersAdolescentsFindingsParticipantsPhrasingAdults
2000
Practice parameter: Screening and diagnosis of autism Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society
Filipek P, Accardo P, Ashwal S, Baranek G, Cook E, Dawson G, Gordon B, Gravel J, Johnson C, Kallen R, Levy S, Minshew N, Ozonoff S, Prizant B, Rapin I, Rogers S, Stone W, Teplin S, Tuchman R, Volkmar F. Practice parameter: Screening and diagnosis of autism Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Child Neurology Society. Neurology 2000, 55: 468-479. PMID: 10953176, DOI: 10.1212/wnl.55.4.468.Peer-Reviewed Original ResearchConceptsQuality Standards SubcommitteeRoutine developmental screeningRoutine developmental surveillanceChild Neurology SocietyLate preschool ageIdentification of childrenCommon disorderDevelopmental screeningPractice parametersDevelopmental surveillanceMost young childrenEarly interventionEarly identificationAmerican AcademyYoung childrenChildrenDevelopmental disordersPreschool ageDisordersRiskSpecific recommendationsScreeningAutismPreschool yearsAutism reportThe Children's Social Behavior Questionnaire for Milder Variants of PDD Problems: Evaluation of the Psychometric Characteristics
Luteijn E, Luteijn F, Jackson S, Volkmar F, Minderaa R. The Children's Social Behavior Questionnaire for Milder Variants of PDD Problems: Evaluation of the Psychometric Characteristics. Journal Of Autism And Developmental Disorders 2000, 30: 317-330. PMID: 11039858, DOI: 10.1023/a:1005527300247.Peer-Reviewed Original ResearchConceptsChildren's Social Behavior QuestionnaireSocial Behavior QuestionnaireChild Behavior ChecklistADHD groupAutism Behavior ChecklistPDDNOS groupBehavior ChecklistBehavior QuestionnaireGood psychometric qualitiesSignificant group differencesChild psychiatric disordersAutism groupInsight ScaleInsight problemBehavior problemsPsychometric qualitiesGroup differencesPsychometric characteristicsStereotypical behaviorsHigher scoresLarge sampleRigid behaviorComparison of groupsScale constructionChildrenToward a Developmental Operational Definition of Autism
Gillham J, Carter A, Volkmar F, Sparrow S. Toward a Developmental Operational Definition of Autism. Journal Of Autism And Developmental Disorders 2000, 30: 269-278. PMID: 11039854, DOI: 10.1023/a:1005571115268.Peer-Reviewed Original ResearchConceptsMental ageSocialization scoresChronological ageDevelopmental disordersVineland Adaptive Behavior ScalesLarge normative sampleDaily living skillsAdaptive behavior scoresTraditional diagnostic schemeDiagnosis of autismAdaptive Behavior ScalesAutism groupIntellectual functioningNormative sampleMaladaptive behaviorsChild communicationVineland scoresDevelopmental levelBasis of socializationSerious maladaptive behaviorsLiving skillsStandardized measuresAutismBehavior ScaleAdaptive behaviorBrief Report: Interrater Reliability of Clinical Diagnosis and DSM-IV Criteria for Autistic Disorder: Results of the DSM-IV Autism Field Trial
Klin A, Lang J, Cicchetti D, Volkmar F. Brief Report: Interrater Reliability of Clinical Diagnosis and DSM-IV Criteria for Autistic Disorder: Results of the DSM-IV Autism Field Trial. Journal Of Autism And Developmental Disorders 2000, 30: 163-167. PMID: 10832781, DOI: 10.1023/a:1005415823867.Peer-Reviewed Original ResearchResearch Units on Pediatric Psychopharmacology (Rupp) Autism Network Background and Rationale for an Initial Controlled Study of Risperidone
McDougle C, Scahill L, McCracken J, Aman M, Tierney E, Arnold L, Freeman B, Martin A, McGough J, Cronin P, Posey D, Riddle M, Ritz L, Swiezy N, Vitiello B, Volkmar F, Votolato N, Walson P. Research Units on Pediatric Psychopharmacology (Rupp) Autism Network Background and Rationale for an Initial Controlled Study of Risperidone. Child And Adolescent Psychiatric Clinics Of North America 2000, 9: 201-224. PMID: 10674197, DOI: 10.1016/s1056-4993(18)30142-1.Peer-Reviewed Original ResearchConceptsOpen-label trialDA neuronal systemsSafety of risperidoneStudy of RisperidonePlacebo-controlled studyUse of risperidoneExtrapyramidal side effectsTarget of pharmacotherapyTreatment of childrenImpaired social behaviorLong-term effectivenessPreclinical evidenceReceptor blockadeTypical antipsychoticsControlled StudyFirst drugPathophysiology of autismLower riskShort-term benefitsSide effectsRisperidonePotent effectsSymptoms of autismNeuronal systemsEnhanced efficacy
1999
Lessons from Secretin
Volkmar F. Lessons from Secretin. New England Journal Of Medicine 1999, 341: 1842-1845. PMID: 10588973, DOI: 10.1056/nejm199912093412412.Peer-Reviewed Original ResearchAsk the Editor
Volkmar F. Ask the Editor. Journal Of Autism And Developmental Disorders 1999, 29: 509-510. PMID: 10638463, DOI: 10.1023/a:1022252004310.Peer-Reviewed Original ResearchPractice parameters for the assessment and treatment of children, adolescents, and adults with autism and other pervasive developmental disorders
Volkmar F, Cook E, Pomeroy J, Realmuto G, Tanguay P, Issues T. Practice parameters for the assessment and treatment of children, adolescents, and adults with autism and other pervasive developmental disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 32s-54s. PMID: 10624084, DOI: 10.1016/s0890-8567(99)80003-3.Peer-Reviewed Original ResearchConceptsPervasive developmental disorderDevelopmental disordersRelated pervasive developmental disordersPatterns of delayCognitive skillsBehavioral problemsSyndrome expressionTreatment of childrenAutismCoordination of servicesPractice parametersTreatment modalitiesSustained interventionsMental retardationIndividualsDisordersClinical careAdolescentsDevianceSkillsFirst yearChildrenCareAdultsInterventionThe Screening and Diagnosis of Autistic Spectrum Disorders
Filipek P, Accardo P, Baranek G, Cook E, Dawson G, Gordon B, Gravel J, Johnson C, Kallen R, Levy S, Minshew N, Prizant B, Rapin I, Rogers S, Stone W, Teplin S, Tuchman R, Volkmar F. The Screening and Diagnosis of Autistic Spectrum Disorders. Journal Of Autism And Developmental Disorders 1999, 29: 439-484. PMID: 10638459, DOI: 10.1023/a:1021943802493.Peer-Reviewed Original ResearchConceptsEvaluation of autismMultidisciplinary consensus panelRoutine developmental surveillanceChild Neurology SocietyAppropriate diagnosisEarly suspicionConsensus panelPractice parametersDevelopmental surveillanceEarly interventionAmerican AcademyDiagnosisNational InstituteAutistic spectrum disorderSpectrum disorderRelevant scientific articlesDetailed recommendationsAutismA Normed Study of Face Recognition in Autism and Related Disorders
Klin A, Sparrow S, de Bildt A, Cicchetti D, Cohen D, Volkmar F. A Normed Study of Face Recognition in Autism and Related Disorders. Journal Of Autism And Developmental Disorders 1999, 29: 499-508. PMID: 10638462, DOI: 10.1023/a:1022299920240.Peer-Reviewed Original ResearchConceptsFace recognition deficitsRecognition deficitsMental ageFace recognitionYoung childrenVerbal mental ageFace recognition abilityNonverbal mental ageGeneral cognitive capacityOverall cognitive abilityChronological agePervasive developmental disorderVerbal abilityNonverbal intelligenceCognitive abilitiesTask demandsCognitive capacityTask performanceComparison taskAutistic groupProcessing peculiaritiesAutismDevelopmental disordersRecognition abilityOlder childrenSeason of Birth in Autism: A Fiction Revisited
Landau E, Cicchetti D, Klin A, Volkmar F. Season of Birth in Autism: A Fiction Revisited. Journal Of Autism And Developmental Disorders 1999, 29: 385-393. PMID: 10587885, DOI: 10.1023/a:1023030911527.Peer-Reviewed Original ResearchHigher-Functioning Pervasive Developmental Disorders: Rates and Patterns of Psychotropic Drug Use
MARTIN A, SCAHILL L, KLIN A, VOLKMAR F. Higher-Functioning Pervasive Developmental Disorders: Rates and Patterns of Psychotropic Drug Use. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 923-931. PMID: 10405512, DOI: 10.1097/00004583-199907000-00024.Peer-Reviewed Original ResearchConceptsPsychotropic drug useHigher-functioning pervasive developmental disordersPervasive developmental disorderTarget symptomsDrug useMedication use patternsPsychotropic medication useDevelopmental disordersMedication history informationMore medicationsMedication useClinical presentationPsychiatric comorbidityClinical variablesPsychotropic agentsDrug classesClinical heterogeneityDisordersSymptomsSubjectsAsperger's disorderFull Scale IQComorbiditiesMedicationsAntidepressantsAsk the Editor
Volkmar F. Ask the Editor. Journal Of Autism And Developmental Disorders 1999, 29: 185-186. PMID: 10382142, DOI: 10.1023/a:1023009230857.Peer-Reviewed Original Research
1998
How Commonly Are Known Medical Conditions Associated with Autism?
Barton M, Volkmar F. How Commonly Are Known Medical Conditions Associated with Autism? Journal Of Autism And Developmental Disorders 1998, 28: 273-278. PMID: 9711483, DOI: 10.1023/a:1026052417561.Peer-Reviewed Original Research