2021
Methylation-based Cell-free DNA Signature for Early Detection of Pancreatic Cancer
Ying L, Sharma A, Chhoda A, Ruzgar N, Hasan N, Kwak R, Wolfgang CL, Wang TH, Kunstman JW, Salem RR, Wood LD, Iacobuzio-Donahue C, Schneider EB, Farrell JJ, Ahuja N. Methylation-based Cell-free DNA Signature for Early Detection of Pancreatic Cancer. Pancreas 2021, 50: 1267-1273. PMID: 34860810, DOI: 10.1097/mpa.0000000000001919.Peer-Reviewed Original Research
2016
Frailty predicts risk of life-threatening complications and mortality after pancreatic resections
Augustin T, Burstein M, Schneider E, Morris-Stiff G, Wey J, Chalikonda S, Walsh R. Frailty predicts risk of life-threatening complications and mortality after pancreatic resections. Surgery 2016, 160: 987-996. PMID: 27545992, DOI: 10.1016/j.surg.2016.07.010.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedCause of DeathComorbidityDatabases, FactualFemaleFrail ElderlyHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPancreatectomyPancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsPredictive Value of TestsRetrospective StudiesRisk AssessmentROC CurveSeverity of Illness IndexSex FactorsSurvival AnalysisTreatment OutcomeConceptsNational Surgical Quality Improvement ProjectSurgical Quality Improvement ProjectGrade 4 complicationsFrailty indexQuality improvement projectGreater body mass indexDistal pancreatectomy patientsModified Frailty IndexOutcomes of pancreatoduodenectomyLow serum albuminLife-threatening complicationsPre-operative optimizationEffect of frailtySelection of patientsBody mass indexDegree of frailtyGreater weight lossImprovement projectIntermediate frailtyNonfrail patientsConsideration of frailtyDistal pancreatectomyFrail patientsOperative riskPancreatectomy patients
2013
Influence of Patient, Physician, and Hospital Factors on 30-Day Readmission Following Pancreatoduodenectomy in the United States
Hyder O, Dodson R, Nathan H, Schneider E, Weiss M, Cameron J, Choti M, Makary M, Hirose K, Wolfgang C, Herman J, Pawlik T. Influence of Patient, Physician, and Hospital Factors on 30-Day Readmission Following Pancreatoduodenectomy in the United States. JAMA Surgery 2013, 148: 1095-1102. PMID: 24108580, PMCID: PMC3983984, DOI: 10.1001/jamasurg.2013.2509.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAttitude of Health PersonnelCohort StudiesComorbidityCross InfectionFemaleHealth Care SurveysHospital MortalityHumansLength of StayMaleMedicareOutcome Assessment, Health CarePancreatic NeoplasmsPancreaticoduodenectomyPatient ReadmissionPostoperative ComplicationsPractice Patterns, Physicians'Retrospective StudiesRisk FactorsSEER ProgramSurvival RateTime FactorsUnited StatesWorkloadConceptsPancreatoduodenectomy proceduresMedical comorbiditiesHospital factorsSurgeon volumeMedicare dataPopulation-based cancer registry dataPreoperative medical comorbiditiesRetrospective cohort studyDays of dischargeHospital-level factorsLow-volume hospitalsPatient-related factorsChance of readmissionLength of stayInfluence of patientCancer registry dataPancreatoduodenectomy patientsHospital morbidityCohort studyHospital volumeHospital readmissionMedian agePhysician factorsDistinct hospitalsPatient level
2012
Patient Readmission and Mortality after Surgery for Hepato-Pancreato-Biliary Malignancies
Schneider E, Hyder O, Wolfgang C, Hirose K, Choti M, Makary M, Herman J, Cameron J, Pawlik T. Patient Readmission and Mortality after Surgery for Hepato-Pancreato-Biliary Malignancies. Journal Of The American College Of Surgeons 2012, 215: 607-615. PMID: 22921328, PMCID: PMC4051393, DOI: 10.1016/j.jamcollsurg.2012.07.007.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBiliary Tract NeoplasmsCohort StudiesDigestive System Surgical ProceduresFemaleHospital MortalityHumansLength of StayLiver NeoplasmsLogistic ModelsMaleMedicareMultivariate AnalysisPancreatic NeoplasmsPatient ReadmissionPostoperative ComplicationsRetrospective StudiesSEER ProgramSurvival AnalysisTreatment OutcomeUnited StatesConceptsRisk of readmissionHepatobiliary proceduresPancreatic proceduresHepatobiliary surgical proceduresMultiple preoperative comorbiditiesEnd Results-MedicareHigher inpatient mortalityPrimary surgical treatmentDays of dischargeIncidence of readmissionProlonged hospital stayProportion of patientsShort-term morbidityNumber of patientsPreoperative comorbiditiesHigher readmissionHospital morbidityHospital stayIndex hospitalAdditional morbidityInpatient mortalityMost patientsPatient agePatient comorbiditiesSurgical treatment